components of nucleotides, with all of these monomers constituting the basic building blocks of nucleic acids. The ability of nucleobases to form base pairs and...
15 KB (1,434 words) - 14:39, 12 August 2024
Nucleotides are organic molecules composed of a nitrogenous base, a pentose sugar and a phosphate. They serve as monomeric units of the nucleic acid polymers...
32 KB (3,305 words) - 22:21, 6 May 2024
bioinformatics, a single-nucleotide polymorphism (SNP /snɪp/; plural SNPs /snɪps/) is a germline substitution of a single nucleotide at a specific position...
58 KB (6,238 words) - 03:17, 12 August 2024
Point mutation (redirect from Nucleotide substitution)
A point mutation is a genetic mutation where a single nucleotide base is changed, inserted or deleted from a DNA or RNA sequence of an organism's genome...
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Adenine (redirect from Adenine nucleotides)
Adenine (/ˈædɪnɪn/) (symbol A or Ade) is a purine nucleotide base. It is one of the four nucleobases in the nucleic acids of DNA, the other three being...
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International Union of Pure and Applied Chemistry (category Organisations based in Zürich)
important work IUPAC has done in these fields includes standardizing nucleotide base sequence code names; publishing books for environmental scientists...
56 KB (2,544 words) - 03:49, 11 June 2024
the Human Genome Project. Phred quality scores are assigned to each nucleotide base call in automated sequencer traces. The FASTQ format encodes phred...
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<Base_1: Base_2><Edge_1: Edge_2><Glycosidic Bond Orientation> where Base_1 and Base_2 carry information on respective base identities and their nucleotide number...
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Single-base extension (SBE) is a method for determining the identity of a nucleotide base at a specific position along a nucleic acid. The method is used...
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suited to the storage of genetic information, while base-pairing between DNA and incoming nucleotides provides the mechanism through which DNA polymerase...
32 KB (3,701 words) - 21:44, 24 August 2024
Dideoxynucleotide (redirect from Di-deoxy nucleotide)
the ddGNTP, is a pattern observed in various research. That is, each nucleotide base of that particular type has a probability of being bonded to not a...
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groups. Like other nucleotides, cyclic nucleotides are composed of three functional groups: a sugar, a nitrogenous base, and a single phosphate group. As can...
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(also called an insertion mutation) is the addition of one or more nucleotide base pairs into a DNA sequence. This can often happen in microsatellite...
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Complementarity (molecular biology) (redirect from Complementary base)
other strand, as occurs in the processes of mismatch repair, nucleotide excision repair and base excision repair. Nucleic acids strands may also form hybrids...
23 KB (2,586 words) - 20:09, 27 March 2024
Nucleic acid analogue (redirect from Base analog)
the most common base analogs is 5-bromouracil (5BU), the abnormal base found in the mutagenic nucleotide analog BrdU. When a nucleotide containing 5-bromouracil...
49 KB (5,299 words) - 17:42, 19 August 2024
primarily for removing small, non-helix-distorting base lesions from the genome. The related nucleotide excision repair pathway repairs bulky helix-distorting...
29 KB (3,493 words) - 00:14, 22 June 2024
wobble base pair is a pairing between two nucleotides in RNA molecules that does not follow Watson-Crick base pair rules. The four main wobble base pairs...
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Arecibo message (section Nucleotides)
vertical bar in the middle is a binary representation of the number of nucleotide base pairs in the human genome. The value depicted is around 4.3 billion...
21 KB (2,118 words) - 22:23, 27 June 2024
Genome editing (redirect from Base editing)
pairs binding site. TALEN can be performed within a 6 base pairs range of any single nucleotide in the entire genome. TALEN constructs are used in a similar...
78 KB (9,362 words) - 13:30, 27 July 2024
frequently in daltons, or as the total number of nucleotide base pairs, usually in megabases (millions of base pairs, abbreviated Mb or Mbp). One picogram...
44 KB (5,102 words) - 17:59, 25 May 2024
also been shown to be reactive towards thiols, many vitamins, the nucleotide base guanine, the trioses glyceraldehyde and dihydroxyacetone, and some...
7 KB (779 words) - 09:31, 20 April 2024
Many of these mutations take the form of single nucleotide polymorphisms in which a single nucleotide base is altered compared to a consensus sequence. They...
4 KB (463 words) - 11:21, 17 October 2022
DNA base flipping, or nucleotide flipping, is a mechanism in which a single nucleotide base, or nucleobase, is rotated outside the nucleic acid double...
30 KB (3,431 words) - 02:56, 4 January 2024
are the non-sex chromosomes. Chromosome 1 spans about 249 million nucleotide base pairs, which are the basic units of information for DNA. It represents...
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Nucleoside triphosphate (redirect from Nucleotide triphosphates)
term nucleoside refers to a nitrogenous base linked to a 5-carbon sugar (either ribose or deoxyribose). Nucleotides are nucleosides covalently linked to...
24 KB (2,528 words) - 15:02, 22 February 2024
single-nucleotide polymorphism is a modification of a single nucleotide base within a DNA sequence. There are an estimated 15 million SNP (Single-nucleotide...
13 KB (1,568 words) - 21:35, 14 August 2024
day, coupled with a high mutation rate of approximately 3 x 10−5 per nucleotide base per cycle of replication and recombinogenic properties of reverse transcriptase...
125 KB (14,365 words) - 18:21, 14 August 2024
Mutagen (section Base analogs)
a chemical addition or disruption of a nucleotide base in DNA (generating an abnormal nucleotide or nucleotide fragment), or a break in one or both strands...
51 KB (5,953 words) - 02:02, 25 July 2024
Nucleic acid sequence (redirect from Nucleotide sequence)
A nucleic acid sequence is a succession of bases within the nucleotides forming alleles within a DNA (using GACT) or RNA (GACU) molecule. This succession...
22 KB (2,409 words) - 23:07, 24 August 2024
Abiogenesis (section Nucleobases and nucleotides)
for organism function. UV is necessary for the formation of the U+C nucleotide base pair by partial hydrolysis and nucleobase loss. Simultaneously, UV...
203 KB (21,024 words) - 11:57, 27 August 2024