Origin recognition complex subunit 2 is a protein that is encoded by the ORC2 (ORC2L) gene in humans. The origin recognition complex (ORC) is a highly...
13 KB (1,480 words) - 02:27, 29 March 2023
origins of replication. The subunits of this complex are encoded by the ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6 genes. ORC is a central component for eukaryotic...
21 KB (2,335 words) - 13:22, 16 August 2023
(preparation in G1 phase) Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5...
60 KB (7,286 words) - 08:26, 2 July 2024
structure of the S. cerevisiae ORC bound to ARS DNA has been determined. Orc1, Orc2, Orc3, Orc4, and Orc5 encircle the A element by means of two types of interactions...
119 KB (14,646 words) - 22:02, 3 July 2024
(preparation in G1 phase) Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5...
113 KB (12,561 words) - 17:02, 14 May 2024
HGNC:21667 Q96SN7 11505 ORAI3 HGNC:28185 Q9BRQ5 11506 ORC1 HGNC:8487 Q13415 11507 ORC2 HGNC:8488 Q13416 11508 ORC3 HGNC:8489 Q9UBD5 11509 ORC4 HGNC:8490 O43929...
282 KB (17 words) - 07:55, 20 June 2024
levels of Ran-GTP inhibit kinetochore release of Bub1, Bub3, Mad2 and CENP-E. Orc2 (a protein that belongs to the origin recognition complex -ORC- implicated...
65 KB (7,839 words) - 18:06, 1 July 2024
(preparation in G1 phase) Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5...
6 KB (634 words) - 22:52, 2 December 2023
(preparation in G1 phase) Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5...
3 KB (336 words) - 09:50, 4 November 2023
association in a contiguous region, spanning 20-50kb. In this direction, Orc2 (one protein included in the origin recognition complex, ORC, implicated...
73 KB (9,149 words) - 03:31, 28 June 2024
methyl CpG binding protein MeCP2, and the origin recognition complex protein ORC2. HP1 has a versatile structure with three main components; a chromodomain...
16 KB (1,880 words) - 20:36, 13 October 2022
include origin recognition complex 2 (Orc2), heterochromatin protein 1 (HP1a), macroH2A1, and Bmil. Disruption of Orc2 or HP1a function have both been shown...
41 KB (5,094 words) - 03:44, 4 May 2024
protein and ORC1 are loosely associated with the core complex consisting of ORC2, -3, -4 and -5. Gene silencing studies with small interfering RNA demonstrated...
9 KB (881 words) - 16:49, 28 October 2022
(preparation in G1 phase) Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5...
6 KB (740 words) - 17:22, 3 December 2023
(preparation in G1 phase) Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5...
2 KB (264 words) - 20:32, 27 March 2024
interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent...
8 KB (990 words) - 21:08, 28 December 2023
(preparation in G1 phase) Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5...
9 KB (1,103 words) - 12:15, 20 March 2024
protein kinase, Cyclin-dependent kinase 2, MCM2, MCM4, MCM6, MCM7, MYST2, ORC2, ORC4, ORC5, and SKP2. GRCh38: Ensembl release 89: ENSG00000085840 – Ensembl...
12 KB (1,433 words) - 06:31, 27 December 2023
described. ORC5 has been shown to interact with: MCM2, MCM3, MCM4, MCM7, ORC1, ORC2, ORC3, and ORC4. GRCh38: Ensembl release 89: ENSG00000164815 – Ensembl, May...
8 KB (983 words) - 23:58, 3 March 2023
Egitto (ORC10)* Margherita d'Anjou (ORC25)* Offenbach Christopher Columbus (ORC2) Fantasio (ORC51)* La Princesse de Trébizonde (ORC63) Robinson Crusoe (ORC7)*...
10 KB (1,025 words) - 00:22, 31 May 2024
reported. ORC4 has been shown to interact with: MCM2, MCM3, MCM4, MCM6, ORC1, ORC2, ORC3, ORC5, and ORC6. GRCh38: Ensembl release 89: ENSG00000115947 – Ensembl...
9 KB (1,126 words) - 19:06, 26 April 2024
reported for this gene. ORC3 has been shown to interact with: MCM4, MCM7, ORC2, ORC4, ORC5, and ORC6. GRCh38: Ensembl release 89: ENSG00000135336 – Ensembl...
9 KB (974 words) - 23:29, 3 March 2023
(preparation in G1 phase) Pre-replication complex Origin recognition complex ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 Cdc6 Cdt1 Minichromosome maintenance MCM2 MCM3 MCM4 MCM5...
4 KB (523 words) - 22:27, 9 September 2023