Olney's lesions, also known as NMDA receptor antagonist neurotoxicity (NAT), is a form of brain damage consisting of selective death of neurons but not...

ALPSA lesion Hill–Sachs lesion Osteoporosis circumscripta Osteolytic lesion Brain lesions Olney's lesions Skin lesions Melanocytic nevus Skip lesion Osler's...

clinically for this purpose because of the discovery of brain lesions, called Olney's lesions (see below), in laboratory rats. Dizocilpine is also associated...

receptor antagonists, PCP can cause a kind of brain damage called Olney's lesions in rats. Studies conducted on rats showed that high doses of the NMDA...

has not been shown to cause vacuolization in animals, also known as Olney's lesions, despite early speculation that it might, due to similarities with...

coined the term excitotoxicity in his 1969 paper published in Science. Olney's lesions are named after him. In 1996 he was elected to the Institute of Medicine...

type 3 Olivopontocerebellar atrophy Ollier disease Olmsted syndrome Olney's lesions Omenn syndrome Omodysplasia type 1 Omodysplasia type 2 Omphalocele...

a form of brain damage called Olney's lesions. NMDA receptor antagonists that have been shown to induce Olney's lesions include ketamine, phencyclidine...

medication contains dextromethorphan, an NMDA receptor antagonist. Olney's lesions involve mass vacuolization of neurons observed in rodents. However...

has been suggested that N 2O produces neurotoxicity in the form of Olney's lesions in rodents upon prolonged (several hour) exposure. It has been argued...

respiratory depression. Dextromethorphan was once thought to cause Olney's lesions when administered intravenously; however, this was later proven inconclusive...

potentially fused or "webbed" (cutaneous syndactyly), and a benign mass or lesion in the brain called a hypothalamic hamartoma. This benign tumor may not...

of confounding infections known to cause lymphoid neoplasmas and other lesions earlier and at greater rates in the test species; pooling of tumors (lymphomas...

doi:10.1001/archopht.1957.00940010205006. PMID 13443577. Olney JW (May 1969). "Brain lesions, obesity, and other disturbances in mice treated with monosodium...

original research by John Olney. In 1989, John Olney discovered that neuronal vacuolation and other cytotoxic changes ("lesions") occurred in brains of...

the colony of British Guiana, Cleveland and Secretary of State Richard Olney protested. British Prime Minister Lord Salisbury and the British ambassador...

widely accepted and has had major implications for the treatment of these lesions. His later interest in movement disorders led him to show the utility of...

to those seen in pellagra, but without the widespread peripheral skin lesions. For this reason, early in the history of identifying riboflavin deficiency...

1016/s0140-6736(84)90539-7. PMID 6147452. S2CID 31985414. Olney JW, Sharpe LG (October 1969). "Brain lesions in an infant rhesus monkey treated with monsodium...

December 2011. Dorland's Medical Dictionary for Health Consumers Spencer 2000 Olney 2002 Kiernan 2005 Lidsky 2003 Heaton; Barrow, Marieta; Mitchell, J. Jean;...

"Ultrasonography of Pediatric Superficial Soft Tissue Tumors and Tumor-Like Lesions". Korean Journal of Radiology. 21 (3): 341–355. doi:10.3348/kjr.2019.0343...