Adenovirus varieties have been explored extensively as a viral vector for gene therapy and also as an oncolytic virus. Of the many different viruses being...

melanoma; the approval was withdrawn in 2019. An oncolytic adenovirus, a genetically modified adenovirus named H101, was approved in China in 2005 for the...

cancer. In China, oncolytic adenovirus is an approved cancer treatment. Specific modifications on fiber proteins are used to target Adenovirus to certain cell...

ONCOS-102 (Ad5/3-D24-GMCSF), (developed by Oncos Therapeutics) is an oncolytic adenovirus previously described as CGTG-102. It is currently in orphan drug...

Adenovirus E1B protein usually refers to one of two proteins transcribed from the E1B gene of the adenovirus: a 55kDa protein and a 19kDa protein. These...

Anna; Pesonen, Sari; Hemminki, Akseli (2014). "Serotype chimeric oncolytic adenovirus coding for GM-CSF for treatment of sarcoma in rodents and humans"...

malignancies. AdVince, a type of gene therapy using a genetically modified oncolytic adenovirus and supported by the crowdfunding campaign iCancer was used in a...

many Oncolytic AAV applications that are in development and have been researched. AAV is a small virus that was found as a contaminant in adenovirus studies...

investigational oncolytic virus that is in clinical trials for various cancers. It is an oncolytic A11/Ad3 Chimeric Group B Adenovirus, previously described...

and vaccine research Producing cell suspension cultures to support oncolytic adenovirus used in cancer immunotherapy Cell culture Adherent culture Bio-MEMS...

Oncolytic Adenovirus Therapy for Brain Tumors Juan Fueyo, M.D., and Candelaria Gomez-Manzano, M.D., create an experimental therapy using adenovirus to...

Åkerström G, Öberg K, Giandomenico V, Essand M (November 2011). "Oncolytic adenovirus modified with somatostatin motifs for selective infection of neuroendocrine...

Åkerström G, Öberg K, Giandomenico V, Essand M (November 2011). "Oncolytic adenovirus modified with somatostatin motifs for selective infection of neuroendocrine...

immunotherapy and especially on oncolytic adenoviruses. The goal of his research group is to create a new oncolytic adenovirus based treatment for cancers...

NK, Choi HJ, Yun CO. VEGF-specific short hairpin RNA–expressing oncolytic adenovirus elicits potent inhibition of angiogenesis and tumor growth. Molecular...

of pancreatic cancer progression and metastasis and developing an oncolytic adenovirus to attack pancreatic tumor stem cells. Vickers also became the principal...

laherparepvec Virotherapy Oncolytic virus Oncolytic adenovirus Herpes simplex virus Varghese S, Rabkin SD (December 2002). "Oncolytic herpes simplex virus...

treat diseases. There are three main branches of virotherapy: anti-cancer oncolytic viruses, viral vectors for gene therapy and viral immunotherapy. These...

Joensuu has led several clinical trials and published articles on oncolytic adenovirus therapy, radiotherapy, chemoradiotherapy and prostate cancer. Dr...

Mesenchymal Stem Cells Used as Carrier Cells of Oncolytic Adenovirus Results in Enhanced Oncolytic Virotherapy, Nature Sci Rep 10, 425 (2020). L.G. de...

cells, especially endothelial cells, is mediated by coxsackievirus and adenovirus receptor. Coxsackieviruses are divided into group A and group B viruses...

of Birmingham. PsiOxus is now developing a cancer-killing 'oncolytic' group B adenovirus 'ColoAd1' in a series of clinical trials to treat cancer. More...

systems could improve the clinical benefit from these types of therapies. Oncolytic virotherapy is an emerging novel treatment that is under investigation...

(July 1980). "Adenovirus helper function for growth of adeno-associated virus: effect of temperature-sensitive mutations in adenovirus early gene region...

was confirmed by a later trial of the same oncolytic virus, and also in Onyx 015, an oncolytic adenovirus. In describing the report authored by Pecora...

PMID 10367824. Chan, Winnie M.; McFadden, Grant (1 September 2014). "Oncolytic Poxviruses". Annual Review of Virology. 1 (1): 119–141. doi:10...

including adenovirus, reovirus, measles, herpes simplex, Newcastle disease virus and vaccinia have now been clinically tested as oncolytic agents. T-Vec...

the immune system. The first oncolytic virus to be approved by a regulatory agency was a genetically modified adenovirus named H101 by Shanghai Sunway...

trials were for cancer treatment.: 7  Adenovirus vectors are useful for some cancer gene therapies because adenovirus can transiently insert genetic material...

adenovirus-based oncolytic virus products for brain cancer. In 2012, Curiel collaborated with scientist Mike Mathis from LSU to test the adenovirus on...