of viruses including adenovirus, reovirus, measles, herpes simplex, Newcastle disease virus, and vaccinia have been clinically tested as oncolytic agents...

Virotherapy Oncolytic virus Oncolytic adenovirus Herpes simplex virus Varghese S, Rabkin SD (December 2002). "Oncolytic herpes simplex virus vectors for cancer...

Herpes simplex virus 1 (cold sores) and 2 (genital herpes) (HSV-1 and HSV-2), also known by their taxonomic names Human alphaherpesvirus 1 and Human alphaherpesvirus...

Talimogene laherparepvec is a genetically engineered herpes virus (an oncolytic herpes virus). Two genes were removed – one that shuts down an individual...

vector for gene therapy and also as an oncolytic virus. Of the many different viruses being explored for oncolytic potential, an adenovirus was the first...

Adeno-associated virus (AAV) has been researched as a viral vector in gene therapy for cancer treatment as an oncolytic virus. Currently there are not...

the virus gained approval for the treatment of melanoma in late 2015. Viruses that have been reprogrammed to kill cancer cells are called oncolytic viruses...

genital herpes respectively, but other members in the herpes family include chickenpox (varicella/zoster), cytomegalovirus, and Epstein-Barr virus. There...

protein Agarwalla PK, Aghi MK (2012). "Oncolytic herpes simplex virus engineering and preparation". Oncolytic Viruses. Methods in Molecular Biology. Vol. 797...

convert viruses into therapeutic agents by reprogramming viruses to treat diseases. There are three main branches of virotherapy: anti-cancer oncolytic viruses...

using viruses. Viruses that have been used for gene therapy are, adenovirus, lentivirus, retrovirus and the herpes simplex virus. The most common virus used...

Teserpaturev is an oncolytic virus for treatment of malignant glioma. Also known as G47∆, teserpaturev is a genetically engineered herpes simplex virus type 1. Originally...

in December 2015 by the EMA, as an oncolytic virotherapy, commercialized by Amgen Inc. This oncolytic herpes virus, named Talimogene laherparepvec, has...

wild-type Coxsackievirus A21, is being used in human clinical trials as an oncolytic virus. SCAR-Fc (Soluble Receptor Analogue) is an experimental prophylactic...

successful, complete inactivation of the virus in a space using a nonthermal plasma generator. Though the oncolytic effect of NDV was already documented in...

The next generation of herpes simplex virus-based oncolytic immunotherapies for cancer treatment". Molecular Therapy Oncolytics. 31: 100729. doi:10.1016/j...

virus in "the wild". Viruses may also be attenuated via reverse genetics. Attenuation by genetics is also used in the production of oncolytic viruses...

2003). "Effective therapy of metastatic ovarian cancer with an oncolytic herpes simplex virus incorporating two membrane fusion mechanisms". Clinical Cancer...

that, despite being present in people infected by helper viruses such as adenovirus or herpes virus, AAV itself did not cause any disease. Wild-type AAV has...

Bexon A, Cattaneo R, Dingli D, Dispenzieri A, et al. (September 2019). "Oncolytic Measles Virotherapy and Opposition to Measles Vaccination". Mayo Clinic...

Campadelli-Fiume is a virologist with a primary research focus on herpes simplex virus, fusion and viral entry. She is a retired professor of virology from...

of viruses including adenovirus, reovirus, measles, herpes simplex, Newcastle disease virus and vaccinia have now been clinically tested as oncolytic agents...

2006). "A mutant type 2 herpes simplex virus deleted for the protein kinase domain of the ICP10 gene is a potent oncolytic virus". Molecular Therapy. 13...

PMID 30996096. "Design and Analysis of Shedding Studies for Virus or Bacteria-Based Gene Therapy and Oncolytic Products; Guidance for Industry | FDA". www.fda.gov...

treatment of solid tumors and hematological malignancies. Pelareorep is an oncolytic virus, which means that it preferentially lyses cancer cells. Pelareorep...

virus shown to target tumors alone Reuters Science, Retrieved 5 September 2012 Garber K (March 2006). "China approves world's first oncolytic virus therapy...

PMID 24936058. Agarwalla PK, Aghi MK (2012). "Oncolytic herpes simplex virus engineering and preparation". Oncolytic Viruses. Methods in Molecular Biology. Vol. 797...

Suryawanshi YR, Schulze AJ (July 2021). "Oncolytic Viruses for Malignant Glioma: On the Verge of Success?". Viruses. 13 (7): 1294. doi:10.3390/v13071294....

vasculature. Talimogene laherparepvec (T-VEC) (which is a herpes simplex virus type 1–derived oncolytic immunotherapy), was shown to be useful against metastatic...

the patient using oncolytic viruses. This approach was used in the drug talimogene laherparepvec, a variant of herpes simplex virus engineered to selectively...