regulatory subunit alpha is an enzyme that in humans is encoded by the PIK3R1 gene. Phosphatidylinositol 3-kinase phosphorylates the inositol ring of...
28 KB (3,136 words) - 20:06, 8 April 2024
delta syndrome is caused by mutations in either of two genes, PIK3CD or PIK3R1, that regulate the maturation of white blood cells, especially B cells and...
9 KB (583 words) - 17:26, 7 February 2024
characteristics and molecular genetic testing that will show a mutation on gene PIK3R1 (5q13.1), which codifies the regulating alpha subunit of phosphatidylinositol...
6 KB (485 words) - 21:43, 24 February 2024
first three regulatory subunits are all splice variants of the same gene (Pik3r1), the other two being expressed by other genes (Pik3r2 and Pik3r3, p85β...
32 KB (3,463 words) - 17:34, 20 November 2023
unknown FGFR2 point mutation 16% unknown KRAS point mutation 10–20% unknown PIK3R1 point mutation 43% unknown TP53 point mutation 10–20% 90% PTEN point mutation...
105 KB (10,821 words) - 12:23, 31 July 2024
GRB7 HCK; HSH2D INPP5D; INPPL1; ITK; JAK2; LCK; LCP2; LYN MATK; NCK1; NCK2 PIK3R1; PIK3R2; PIK3R3; PLCG1; PLCG2; PTK6; PTPN11; PTPN6; RASA1 SH2B1; SH2B2;...
13 KB (1,341 words) - 04:09, 6 March 2024
O00329 12159 PIK3CG HGNC:8978 P48736 12160 PIK3IP1 HGNC:24942 Q96FE7 12161 PIK3R1 HGNC:8979 P27986 12162 PIK3R2 HGNC:8980 O00459 12163 PIK3R3 HGNC:8981 Q92569...
282 KB (17 words) - 18:42, 6 October 2024
CD81, CD9, CRK, CRKL, DOK1, FES, GRB10, Grb2, KITLG, LNK, LYN, MATK, MPDZ, PIK3R1, PTPN11, PTPN6, STAT1, SOCS1, SOCS6, SRC, and TEC. Cytokine receptor List...
35 KB (4,117 words) - 00:12, 6 August 2024
homodimerization. CD28 has been shown to interact with: GRAP2, Grb2, and PIK3R1. List of human clusters of differentiation GRCh38: Ensembl release 89: ENSG00000178562...
22 KB (2,834 words) - 03:10, 29 September 2024
shown to interact with: DNAJA3 EGFR EPOR FYN Grb2 GHR IRS1 IL12RB2 IL5RA PIK3R1 PPP2R4 PTK2 PTPN11 PTPN6 PRMT5 SH2B1 SHC1 SOCS3 STAT5A STAT5B STAM SOCS1...
28 KB (3,166 words) - 19:57, 8 August 2024
PASLI disease can all be caused by heterozygous splice site mutation in PIK3R1, which encodes the p85α, p55α, and p50α regulatory PI3K subunits. These...
11 KB (1,244 words) - 15:20, 27 October 2023
shown to interact with: CDC42, CRKL, EGFR, FGR, FYN, Grb2, ITK ITSN2, NCK1, PIK3R1, PLCG1, PSTPIP1, Src, TRIP10, and WIPF1. Wiskott–Aldrich syndrome-like cortactin...
21 KB (2,588 words) - 00:21, 5 February 2024
shown to interact with TENC1. Also, it interacts with CBL, GRB2, LCK, NCK2, PIK3R1, PIK3R2, PIK3R3, PLCG1, SOCS1, and TNS2. GRCh38: Ensembl release 89: ENSG00000167601...
19 KB (2,361 words) - 14:11, 26 September 2024
GMIP; GRLF1; HMHA1; INPP5B; KIAA1688; LOC553158; MYO9A; MYO9B; OCRL; OPHN1; PIK3R1; PIK3R2; PRR5; RACGAP1; RACGAP1P; RALBP1; RICH2; RICS; SH3BP1; SLIT1; SNX26;...
4 KB (308 words) - 08:47, 20 January 2024
MST1R, MUC1, Mitogen-activated protein kinase 9, NCKIPSD, NEU3, PDGFRB, PIK3R1, PLCG1, PRKAR1A, PTK2, PTPN11, PTPN12, PTPN1, PTPN6, PTPRA, RAPGEF1, RET...
82 KB (9,365 words) - 15:39, 31 March 2024
development. Cluster of differentiation DC-7 CD7 has been shown to interact with PIK3R1. CD7 can be aberrantly expressed in refractory anaemia with excess blasts...
10 KB (1,221 words) - 05:59, 25 December 2023
described for this gene. LTK has been shown to interact with IRS-1, Shc, and PIK3R1. GRCh38: Ensembl release 89: ENSG00000062524 – Ensembl, May 2017 GRCm38:...
7 KB (857 words) - 08:38, 26 December 2023
concerted activity) with: Bcl-2, Grb2, INSR, IGF1R, JAK1, JAK2, MAPK8, PIK3R1 PIK3R3, PTK2, PTPN11, PTPN1, and YWHAE. IRS-1, as a signalling adapter protein...
34 KB (4,304 words) - 07:20, 3 September 2024
effective memory response, extending protection. PIK3CD interacts with PIK3R1, and PIK3R2. Phosphoinositide 3-kinase inhibitor GRCh38: Ensembl release...
23 KB (2,500 words) - 17:09, 28 June 2024
shown to interact with: CD43, FASLG, ICAM-1, ICAM2, ICAM3, Merlin, MSN, PIK3R1, PALLD S100P, SDC2, SLC9A3R1, SLC9A3R2, and VCAM-1. GRCh38: Ensembl release...
12 KB (1,381 words) - 03:18, 15 April 2024
in brain mass. IRS2 has been shown to interact with: PLCG1, SOCS1, and PIK3R1, GRCh38: Ensembl release 89: ENSG00000185950 – Ensembl, May 2017 GRCm38:...
12 KB (1,479 words) - 01:31, 28 November 2023
to interact with: CRKL, Epidermal growth factor receptor, Grb2, NEDD4, PIK3R1, and SH3KBP1. GRCh38: Ensembl release 89: ENSG00000114423 – Ensembl, May...
12 KB (1,393 words) - 05:38, 23 March 2024
GRB7, Grb2, IRS1, ITGB5, JAK2, MAPK8IP3, NCK1, NCK2, NEDD9, NEO1, P53, PIK3R1, PTEN, PXN, RB1CC1, STAT1, Src, Syk, TGFB1I1, TLN1, TSC2, YAP1. Tyrosine...
41 KB (4,724 words) - 09:43, 11 December 2023
T cells has been shown to interact with: GRAP2, GRAP, Grb2, ITK, MAP4K1 PIK3R1, PLCG1, SHB, VAV1, and ZAP-70. GRCh38: Ensembl release 89: ENSG00000213658...
19 KB (2,288 words) - 20:03, 3 April 2024
AGAP2 gene. CENTG1 has been shown to interact with: EPB41L1, HOMER1 and PIK3R1. GRCh38: Ensembl release 89: ENSG00000135439 – Ensembl, May 2017 GRCm38:...
8 KB (971 words) - 00:57, 4 March 2023
for this gene. GAB1 has been shown to interact with: CRKL, Grb2, MAP3K3, PIK3R1, PLCG1 and PTPN11. GRCh38: Ensembl release 89: ENSG00000109458 – Ensembl...
13 KB (1,611 words) - 17:10, 22 December 2023
receptor 1, Linker of activated T cells, Lymphocyte cytosolic protein 2, PIK3R1, Src, VAV1, and ZAP-70. GRCh38: Ensembl release 89: ENSG00000107338 – Ensembl...
8 KB (1,026 words) - 04:20, 24 December 2023
shown to interact with: CRKL, Erythropoietin, Grb2, Janus kinase 2, LYN, PIK3R1, PTPN6, SOCS2, SOCS3, and STAT5A. GRCh38: Ensembl release 89: ENSG00000187266...
28 KB (3,409 words) - 18:05, 8 June 2024
EPH receptor A2 has been shown to interact with: Ephrin A1 ACP1 Grb2, PIK3R1, and SHC1. It was also shown that doxazosin is a small molecule agonist...
11 KB (1,340 words) - 00:34, 2 June 2024
CSF1R. CRK, CRKL, EGFR,< FRS2, FYN, Grb2, HCK, IGF1R, LCP2, NCK1, PDGFRA, PIK3R1, PIK3R2, PLCG1, PTK2B, PTPN11, SH2B2, SH3KBP1 SHC1, SLA2, SORBS1, SORBS2...
33 KB (3,818 words) - 20:19, 2 October 2024