• Thumbnail for PPARGC1A
    1-alpha (PGC-1α) is a protein that in humans is encoded by the PPARGC1A gene. PPARGC1A is also known as human accelerated region 20 (HAR20). It may, therefore...
    28 KB (3,324 words) - 06:25, 3 June 2024
  • patients may help to elucidate otherwise hidden causes of this disease. The PPARGC1A gene regulates genes involved in energy metabolism. Since type 2 diabetes...
    36 KB (4,682 words) - 15:54, 2 April 2024
  • Thumbnail for Pparg coactivator 1 alpha
    PPARG coactivator 1 alpha is a protein that in humans is encoded by the PPARGC1A gene. The protein encoded by this gene is a transcriptional coactivator...
    5 KB (637 words) - 08:17, 11 March 2024
  • Thumbnail for Skeletal muscle
    regulate gene expression and enzyme activity in skeletal muscle. PGC1-α (PPARGC1A), a transcriptional coactivator of nuclear receptors important to the regulation...
    120 KB (13,834 words) - 11:46, 13 June 2024
  • Thumbnail for Peroxisome proliferator-activated receptor gamma
    Tetrahydrocannabivarin Cannabidiol Anandamide CD36 EDF1 EP300 HDAC3 NCOA4 NR0B2 PPARGC1A RB1. miR3666 PPAR-gamma agonists have been used in the treatment of hyperlipidaemia...
    19 KB (2,091 words) - 05:22, 13 July 2024
  • Thumbnail for Human accelerated regions
    HAR07:  ? HAR08: POU6F2 HAR09: PTPRT HAR10: FHIT HAR11: DMD HAR12: ? HAR20: PPARGC1A HAR21: NPAS3 - association with psychiatric disorders [citation needed]...
    6 KB (638 words) - 15:02, 12 July 2024
  • Thumbnail for Tesaglitazar
    to mitochondrial toxicity caused by decrease in PPARγ coactivator 1-α (PPARGC1A, PGC1α) and sirtuin 1 (SIRT1). Wilding JP, Gause-Nilsson I, Persson A (September...
    5 KB (196 words) - 12:15, 13 August 2023
  • Thumbnail for Gene doping
    Endurance ACE Alu I/D (rs4646994) (Called ACE I) ACTN3 577X PPARA rs4253778 G, PPARGC1A Gly482; power/strength markers ACE Alu I/D (rs4646994) (called ACE D) ACTN3...
    32 KB (3,911 words) - 14:38, 6 June 2024
  • Thumbnail for Thyroid hormone receptor beta
    been shown to interact with: BRD8, CCND1, NCOA1, NCOA6, NCOR2, NR2F6, PPARGC1A, and RXRA. GRCh38: Ensembl release 89: ENSG00000151090 – Ensembl, May 2017...
    15 KB (1,743 words) - 14:09, 6 August 2024
  • Thumbnail for FBXW7
    been found for this gene. FBXW7 has been shown to interact with: MYB, PPARGC1A, Parkin (ligase), and SKP1A. GRCh38: Ensembl release 89: ENSG00000109670...
    12 KB (1,515 words) - 02:37, 30 March 2024
  • Thumbnail for DNM1L
    alter Drp1 activity through gene expression and regulation. For example, PPARGC1A and [HIF1A] regulated Drp1 activity through gene expression. Inhibition...
    21 KB (2,586 words) - 19:21, 27 March 2024
  • Thumbnail for PRDM16
    significant up-regulation of brown-fat selective genes UCP-1, CIDEA, and PPARGC1A. This up-regulation lead to the development of a BAT-like phenotype within...
    12 KB (1,680 words) - 14:26, 27 January 2024
  • factor) PCAF PGC1 (proliferator activated receptor gamma coactivator 1) PPARGC1A (PPARGC1A) PPARGC1B (PPARGC1B) PNRC (proline-rich nuclear receptor coactivator...
    9 KB (1,039 words) - 04:15, 25 March 2024
  • Thumbnail for MED17
    initiation factors and cofactors. MED17 has been shown to interact with PPARGC1A, Cyclin-dependent kinase 8 and BRCA1. GRCh38: Ensembl release 89: ENSG00000042429...
    10 KB (1,139 words) - 02:40, 16 July 2024
  • Q07869 12583 PPARD HGNC:9235 Q03181 12584 PPARG HGNC:9236 P37231 12585 PPARGC1A HGNC:9237 Q9UBK2 12586 PPARGC1B HGNC:30022 Q86YN6 12587 PPAT HGNC:9238...
    282 KB (17 words) - 07:55, 20 June 2024
  • Thumbnail for MED12
    receptor, Cyclin-dependent kinase 8 Estrogen receptor alpha, Gli3, G9a, PPARGC1A, MED26, SOX9, and Thyroid hormone receptor alpha. GRCh38: Ensembl release...
    14 KB (1,784 words) - 02:14, 19 June 2024
  • Thumbnail for PPARGC1B
    coactivator 1-beta is a protein that in humans is encoded by the PPARGC1B gene. PPARGC1A Peroxisome proliferator-activated receptor Peroxisome proliferator-activated...
    8 KB (1,007 words) - 22:46, 3 March 2023
  • Thumbnail for NRF1
    and mitochondrial function. NRF1 has been shown to interact with DYNLL1, PPARGC1A, and PPRC1. GRCh38: Ensembl release 89: ENSG00000106459 – Ensembl, May...
    12 KB (1,451 words) - 20:13, 3 April 2024
  • Thumbnail for MED1
    alpha, Glucocorticoid receptor, Hepatocyte nuclear factor 4 alpha, P53, PPARGC1A, TGS1, and Thyroid hormone receptor alpha. This entry represents subunit...
    16 KB (1,904 words) - 20:08, 8 June 2024
  • Thumbnail for RNA recognition motif
    P14; PABPC1; PABPC1L; PABPC3; PABPC4; PABPC5; PABPN1; POLDIP3; PPARGC1; PPARGC1A; PPARGC1B; PPIE; PPIL4; PPRC1; PSPC1; PTBP1; PTBP2; PUF60; RALY; RALYL;...
    12 KB (812 words) - 16:58, 7 August 2024
  • Thumbnail for Nuclear receptor coactivator 1
    DDX5 and Estrogen receptor alpha, Glucocorticoid receptor, NFKB1, PCAF, PPARGC1A, Peroxisome proliferator-activated receptor alpha, SNW1, STAT3, STAT6,...
    15 KB (1,725 words) - 17:17, 1 July 2024
  • Thumbnail for PDK4
    cumulative effect across many exercise sessions. The mRNA of PDK4, along with PPARGC1A, increases in both types of muscle tissue after exercise. These metabolic...
    20 KB (2,535 words) - 17:29, 31 May 2023
  • Thumbnail for MED14
    escape chromosome X-inactivation. MED14 has been shown to interact with PPARGC1A, Estrogen receptor alpha, STAT2, Cyclin-dependent kinase 8, Glucocorticoid...
    14 KB (1,446 words) - 13:35, 2 August 2023
  • Thumbnail for SEC16B
    "Association study of common polymorphisms in MSRA, TFAP2B, MC4R, NRXN3, PPARGC1A, TMEM18, SEC16B, HOXB5 and OLFM4 genes with obesity-related traits among...
    10 KB (1,228 words) - 02:34, 19 December 2023
  • Paulmichl M, Landwehrmeyer GB, Weydt P, Patsch W. A greatly extended PPARGC1A genomic locus encodes several new brain specific isoforms and influences...
    14 KB (1,628 words) - 19:30, 31 May 2023
  • Thumbnail for Retinoid X receptor alpha
    LXR-β, MyoD, NCOA6, NFKBIB, NPAS2, NRIP1, NR4A1, NCOA2, NCOA3, POU2F1, PPARGC1A, PPAR-γ, RNF8, RAR-α, SHP, TADA3L, TBP, TRIM24, TR-β, and VDR. Retinoid...
    25 KB (2,892 words) - 21:07, 15 November 2023
  • Thumbnail for Cytochrome b-245, alpha polypeptide
    LO, Zateyshchikov DA, Nosikov VV (May 2010). "Association of the CYBA, PPARGC1A, PPARG3, and PPARD gene variants with coronary artery disease and metabolic...
    37 KB (4,853 words) - 00:44, 28 March 2024