• Thumbnail for Pembrolizumab
    Pembrolizumab, sold under the brand name Keytruda, is a humanized antibody, more specifically a PD-1 Inhibitor, used in cancer immunotherapy that treats...
    80 KB (7,412 words) - 02:30, 16 October 2024
  • As adjuvant therapy, mRNA-4157 monotherapy and in combination with pembrolizumab have been investigated in patients with resected solid tumors (melanoma...
    9 KB (899 words) - 20:37, 28 April 2024
  • Thumbnail for Non-small-cell lung cancer
    system. Atezolizumab is an anti PD-L1 monoclonal antibody. Nivolumab and Pembrolizumab are anti PD-1 monoclonal antibodies. Ipilimumab is a monoclonal antibody...
    51 KB (5,333 words) - 22:13, 7 September 2024
  • Favezelimab/pembrolizumab is a fixed-dose combination of two monoclonal antibodies developed by Merck to treat various cancers. Timmerman, John; Lavie...
    7 KB (422 words) - 20:10, 24 April 2024
  • treatment options. Pembrolizumab monotherapy is an appealing approach for these patients, with median OS of 30 months with pembrolizumab single agent compared...
    60 KB (6,590 words) - 06:01, 15 September 2024
  • Thumbnail for PD-1 and PD-L1 inhibitors
    immunotherapy drugs blocking LAG3, B7-H3, KIR, OX40, PARP, CD27, and ICOS. Pembrolizumab (Keytruda, formerly MK-3475 and lambrolizumab) was developed by Merck...
    35 KB (3,450 words) - 03:38, 30 September 2024
  • Thumbnail for Cancer immunotherapy
    checkpoint inhibitors include antibodies such as ipilimumab, nivolumab, and pembrolizumab. Dendritic cell therapy provokes anti-tumor responses by causing dendritic...
    92 KB (12,517 words) - 05:38, 1 October 2024
  • Thumbnail for Vivian Campbell
    undergoing treatment every three weeks with pembrolizumab. In 2023, he announced that the pembrolizumab was waning in effectiveness and chemotherapy...
    20 KB (2,079 words) - 19:00, 15 October 2024
  • It is being tested by itself and in a fixed-dose combination with pembrolizumab. Garralda, E.; Sukari, A.; Lakhani, N. J.; Patnaik, A.; Lou, Y.; Im...
    7 KB (511 words) - 20:09, 24 April 2024
  • advanced NSCLC but with high PD-L1 levels, who will be treated with pembrolizumab in combination with CIMAvax instead of nivolumab. As of 2023, accural...
    16 KB (1,556 words) - 23:09, 17 July 2024
  • Thumbnail for Merck & Co.
    drugs or products, each with over $1 billion in revenue: Keytruda (pembrolizumab), a humanized antibody used in cancer immunotherapy that had $14.3 billion...
    98 KB (9,657 words) - 08:07, 15 October 2024
  • Thumbnail for Jimmy Carter
    liver, and that he had begun treatment with the immunotherapy drug pembrolizumab and was about to start radiation therapy. His healthcare was managed...
    337 KB (30,109 words) - 21:18, 20 October 2024
  • chemoresistant MSI-high tumors can be treated with dostarlimab and pembrolizumab. In the European Union, dostarlimab is indicated as monotherapy for...
    37 KB (3,213 words) - 00:29, 30 September 2024
  • Thumbnail for Durvalumab
    Immunotherapy: mechanism of action for Durvalumab, Pembrolizumab, Ipilimumab, Atezolizumab....
    28 KB (2,721 words) - 04:14, 1 October 2024
  • quality-assured biosimilars Afatinib and gefitinib are alternatives Pembrolizumab is an alternative, including quality-assured biosimilars Enzalutamide...
    67 KB (4,835 words) - 05:59, 17 August 2024
  • Thumbnail for Breast cancer
    for those whose tumors express PD-L1. And the similar immunotherapy pembrolizumab for those whose tumors have mutations in various DNA repair pathways...
    135 KB (15,182 words) - 15:11, 20 October 2024
  • Thumbnail for Lung cancer
    PD-L1, but are sometimes effective in those that do not. Treatment with pembrolizumab, atezolizumab, or combination nivolumab plus ipilimumab are all superior...
    90 KB (9,784 words) - 07:53, 10 October 2024
  • Thumbnail for Adenocarcinoma of the lung
    inhibitors have been approved for NSCLC, including anti-PD-1 nivolumab and pembrolizumab. Anti-PD-1 agents are used for patients with advanced NSCLC whose tumors...
    42 KB (4,603 words) - 02:26, 2 September 2024
  • Thumbnail for Chordoma
    response rate with median progression free survival of 10.5 months Pembrolizumab: 12% objective response rate with median progression free survival of...
    21 KB (2,187 words) - 14:39, 28 May 2024
  • Thumbnail for Mucosal melanoma
    clinical and observational studies, immune checkpoint inhibitors (e.g., pembrolizumab) have been tested in mucosal melanomas and have shown promising response...
    5 KB (435 words) - 00:01, 9 June 2024
  • Thumbnail for Prostate cancer
    repair benefit from treatment with the immune checkpoint inhibitor drug pembrolizumab and PARP inhibitors, namely olaparib, rucaparib, or niraparib. Bone...
    77 KB (8,910 words) - 03:34, 16 October 2024
  • Thumbnail for Programmed cell death protein 1
    2014 and by the US FDA in December 2014 to treat metastatic melanoma. Pembrolizumab (Keytruda, MK-3475, Merck), which also targets PD-1 receptors, was approved...
    39 KB (5,010 words) - 05:27, 17 August 2024
  • Thumbnail for Atezolizumab
    system. Atezolizumab is an anti PD-L1 monoclonal antibody. Nivolumab and pembrolizumab are anti PD-1 monoclonal antibodies. Ipilimumab is a monoclonal antibody...
    43 KB (4,183 words) - 04:17, 1 October 2024
  • Thumbnail for Interstitial nephritis
    (e.g. sunitinib), checkpoint inhibitors (e.g. ipilimumab, nivolumab, pembrolizumab, atezolizumab) Contrast agent Gadolininum based contrast agent Other...
    20 KB (2,303 words) - 18:34, 27 July 2024
  • Thumbnail for Targeted therapy
    licensed monoclonal antibodies include: Pembrolizumab (Keytruda) binds to PD-1 proteins found on T cells. Pembrolizumab blocks PD-1 and help the immune system...
    20 KB (2,234 words) - 01:21, 22 July 2024
  • Thumbnail for List of therapeutic monoclonal antibodies
    Retrieved 21 August 2020. "Keytruda- pembrolizumab injection, powder, lyophilized, for solution Keytruda- pembrolizumab injection, solution". DailyMed. 17...
    137 KB (4,083 words) - 21:25, 19 October 2024
  • Thumbnail for Hodgkin lymphoma
    cytotoxic component MMAE, and the checkpoint inhibitors, Nivolumab and Pembrolizumab. This has been an important step in the treatment for the few, but still...
    87 KB (8,525 words) - 06:47, 19 October 2024
  • Thumbnail for Nivolumab
    inhibitors PD-1 inhibitorsTooltip Programmed cell death protein 1 Nivolumab Pembrolizumab Cemiplimab Dostarlimab Retifanlimab Toripalimab PD-L1 inhibitorsTooltip...
    46 KB (4,813 words) - 05:06, 15 October 2024
  • Thumbnail for Pemetrexed
    Pemetrexed is also recommended in combination with carboplatin and pembrolizumab for the first-line treatment of advanced non-small cell lung cancer...
    16 KB (1,212 words) - 15:30, 26 September 2024
  • inhibitors PD-1 inhibitorsTooltip Programmed cell death protein 1 Nivolumab Pembrolizumab Cemiplimab Dostarlimab Retifanlimab Toripalimab PD-L1 inhibitorsTooltip...
    9 KB (603 words) - 00:28, 30 September 2024