Phosphoribosylamine (PRA) is a biochemical intermediate in the formation of purine nucleotides via inosine-5-monophosphate, and hence is a building block...

Phosphoribosylamine—glycine ligase, also known as glycinamide ribonucleotide synthetase (GARS), (EC 6.3.4.13) is an enzyme that catalyzes the chemical...

possibility. Inosinate and many other molecules inhibit the synthesis of 5-phosphoribosylamine from 5-phosphoribosyl-1-pyrophosphate (PRPP), disabling the enzyme...

committed step is the reaction of PRPP, glutamine and water to 5'-phosphoribosylamine (PRA), glutamate, and pyrophosphate - catalyzed by amidophosphoribosyltransferase...

health authorities to identify appropriate phytosanitary measures Phosphoribosylamine, a biochemical intermediate Physical Review A, a scientific journal...

the enzyme amidophosphoribosyltransferase acts upon PRPP to create phosphoribosylamine. The histidine biosynthesis pathway involves the reaction between...

+ NH3 ⇌ {\displaystyle \rightleftharpoons } ADP + phosphate + 5-phosphoribosylamine The 3 substrates of this enzyme are ATP, ribose 5-phosphate, and...

ribose-phosphate diphosphokinase (PRPS1). PRPP is then converted to 5-phosphoribosylamine (5-PRA) as glutamine donates an amino group to the C-1 of PRPP. In...

enzyme transfers the amino group from glutamine to PRPP, forming 5-phosphoribosylamine. The following step requires the activation of glycine by the addition...

from GAR. GAR is the product of the enzyme phosphoribosylamine—glycine ligase acting on phosphoribosylamine (PRA) to combine it with glycine in a process...

J. Rudolph; J. Stubbe (1995). "Investigation of the Mechanism of Phosphoribosylamine Transfer from Glutamine Phosphoribosylpyrophosphate Amidotransferase...

the activation of R5P to PRPP, which is later catalyzed to become phosphoribosylamine, a nucleotide precursor. During the purine salvage pathway,...

the GART gene. This protein is a trifunctional polypeptide. It has phosphoribosylamine—glycine ligase (EC 6.3.4.13), phosphoribosylglycinamide formyltransferase...

edited at WikiPathways: "FluoropyrimidineActivity_WP1601". PRPP 5-phosphoribosylamine GRCh38: Ensembl release 89: ENSG00000128059 – Ensembl, May 2017 GRCm38:...

the regulation of the purF gene whose encoded enzyme synthesizes phosphoribosylamine". RNA. 26 (12): 1838–1846. doi:10.1261/rna.077313.120. PMC 7668255...

the apparent 5' UTR of purD genes. purD genes encode the enzyme Phosphoribosylamine-glycine ligase, which catalyzes an early step in de novo purine synthesis...

biosynthesis are highly reactive and can spontaneously break down to 5-phosphoribosylamine and Maillard reaction products, which are highly reactive and harmful...

ammonia from glutamine to the ribotide at its anomeric carbon, forming phosphoribosylamine (PRA): PRPP + glutamine → PRA + glutamate + PPi Next, PRA is converted...

ligase EC 6.3.1.2: glutamine synthetase EC 6.3.1.3: Now EC 6.3.4.13, phosphoribosylamine—glycine ligase EC 6.3.1.4: aspartate—ammonia ligase (ADP-forming)...

reactions, which include PRPP combining with glutamine to form 5-phosphoribosylamine. This reaction is catalyzed by PRPP synthetase. Once IMP is synthesized...