medical genetics and other medical fields, a proband, propositus (male proband), or proposita (female proband) is a particular subject (human or other animal)...

tumor (except breast cancer if the proband has breast cancer) before age 56 years or with multiple tumors; OR A proband with multiple tumors (except multiple...

a person's direct ancestors in a fixed sequence of ascent: Subject (or proband) Father Mother Paternal grandfather Paternal grandmother Maternal grandfather...

mutation. The aniridic probands showed typical features of sclerocornea with nystagmus in proband 28–1 (A); Foveal hypoplasia in proband 27–1 (B); Ptosis,...

person's direct ancestors in a fixed sequence of ascent. The subject (or proband) of the ahnentafel is listed as No. 1, the subject's father as No. 2 and...

the index case is the case of the original patient (i.e. propositus or proband) that stimulates investigation of other members of the family to discover...

carrier is 2/3. Heterozygotes (carriers) are asymptomatic. Offspring of a proband are obligate heterozygotes and will therefore carry one mutant allele....

correlated. So, if Proband A has more older brothers than Proband B, chances are that Proband A also has more older sisters than Proband B. These findings...

nervosa and OCD, suggesting a strong etiology. First and second relatives of probands with OCD have a greater chance of developing anorexia nervosa as genetic...

parent of the proband is affected, the risk to the siblings is 50%. When the parents are clinically unaffected, the risk to the sibs of a proband appears to...

judicial practice by which the guilt or innocence of the accused (called a "proband") was determined by subjecting them to a painful, or at least an unpleasant...

of bipolar disorder overlaps with heritable components of creativity. Probands of people with bipolar disorder are more likely to be professionally successful...

5-hydroxytryptamine in normal human blood and urine. [...] In 11 of 37 probands N,N-dimethyltryptamine was demonstrated in blood (...). In the urine 42...

Barton JC, Barton JC (2015). "Autoimmune Conditions in 235 Hemochromatosis Probands with HFE C282Y Homozygosity and Their First-Degree Relatives". Journal...

Typical prolactin values Proband Prolactin, μg/L (ng/mL) women, follicular phase (n = 803) 12.1 women, luteal phase (n = 699) 13.9 women, mid-cycle (n...

the probands of 4,784 firstborn homosexual men and 40,197 first-born heterosexual men across 6 datasets that found that the homosexual probands had significantly...

a genetic disorder has been identified. This individual, known as the proband, is indicated on the pedigree by an arrow. These changes may occur yearly...

asymptomatic family members after the diagnosis has been confirmed in a proband. The treatment goal for individuals affected with OTC deficiency is the...

Study). He has also criticized the study for starting just with white male probands. Waldinger writes about scientific approaches to healthy human development...

OCD, suggesting a strong etiology. First and second hand relatives of probands with OCD have a greater risk of developing anorexia nervosa as genetic...

data suggest that the Type 1 probands die mainly from cancer, type 2 from CHD, whereas Type 3 and especially Type 4 probands show a much lower death rate...

genes usually results in an embryonically lethal outcome, and should the proband come to term, experience a severe form of Fanconi anemia. Treatment with...

E; Aubourg, P (August 2005). "X-linked adrenoleukodystrophy in a female proband: clinical presentation, biological diagnosis and family consequences"....

conducted by counting the number of times (within a given period of time) a proband performs the typical acts. One element of David Buss' research involves...

gene in Rett syndrome patients, including a familial case with a male proband". European Journal of Human Genetics. 15 (12): 1218–29. doi:10.1038/sj...

genetic testing of APC if the disease-causing mutation is known in the proband [person first identified with the condition] or (b) for clinical manifestations...

approval, approve, improbability, improbable, probability, probable, proband, probate, probation, probationary, probative, probity, reprobate, reproval...

bipolar is estimated at 79%-93%, and first degree relatives of bipolar probands have a relative risk of developing bipolar around 7–10. While the heritability...

schizophrenia-spectrum personality disorders in first-degree relatives of schizophrenia probands". Schizophrenia Research. 68 (2–3): 309–317. doi:10.1016/S0920-9964(03)00081-1...

test with intramuscular injection of halothane 5 and 6 vol% to detect probands at risk for malignant hyperthermia". Anaesthesia. 62 (9): 882–7. doi:10...