A protecting group or protective group is introduced into a molecule by chemical modification of a functional group to obtain chemoselectivity in a subsequent...
57 KB (6,755 words) - 23:19, 9 April 2024
protecting group (Fmoc) is a base-labile protecting group used in organic synthesis. Fmoc carbamate is frequently used as a protecting group for amines...
6 KB (682 words) - 13:54, 31 July 2024
tert-butyloxycarbonyl protecting group or tert-butoxycarbonyl protecting group (BOC group) is an acid-labile protecting group used in organic synthesis. The BOC group can...
10 KB (1,045 words) - 17:06, 19 July 2024
A protected group, protected class (US), or prohibited ground (Canada) is a category by which people are qualified for special protection by a law, policy...
6 KB (648 words) - 20:48, 21 August 2024
A photolabile protecting group (PPG; also known as: photoremovable, photosensitive, or photocleavable protecting group) is a chemical modification to a...
40 KB (4,529 words) - 08:06, 18 June 2024
deprotection of benzyl group are applicable for cleavage of the PMB protecting group The benzyl group is occasionally used as a protecting group for amines in...
15 KB (1,604 words) - 15:45, 3 December 2023
Peptide synthesis (section Protecting groups schemes)
condensation reaction of the carboxyl group of one amino acid to the amino group of another. Protecting group strategies are usually necessary to prevent...
54 KB (6,100 words) - 16:21, 3 August 2024
(tBu) ether is an acid-labile protecting group for alcohols. A traditional way to introduce the tBu group to a hydroxyl group is by treating the compound...
8 KB (874 words) - 22:07, 1 March 2024
Triphenylmethane (section Protecting group)
called trityl, is widely used in organic chemistry. Trityl serves as a protecting group for alcohols. protection (requires proton acceptor): Ph3CCl + ROH →...
8 KB (614 words) - 11:00, 29 July 2024
deprotection of the protected sensitive part of a molecule. The deprotection mechanism has been proven only for several Thermolabile Protecting Groups (TPGs). Most...
3 KB (368 words) - 00:29, 24 November 2022
nucleophile. A tosyl group can function as a protecting group in organic synthesis. Alcohols can be converted to tosylate groups so that they do not react...
7 KB (781 words) - 19:17, 13 April 2024
points for fusion with the A ring. Alcohol 12 was protected by a benzyl group. The acetonide protecting group was removed from the ketone. Ketone 14 was converted...
15 KB (1,399 words) - 13:35, 26 August 2024
BOC Group may refer to: Bank of China Group (BOCG), simplified Chinese: 中银集团; traditional Chinese: 中銀集團 Boc group, a protecting group used in organic...
284 bytes (68 words) - 01:19, 11 November 2023
allowing for the use of the fluorenylmethyloxycarbonyl group (Fmoc) as an orthogonal protecting group. Di-tert-butyl dicarbonate is inexpensive, so it is...
13 KB (1,222 words) - 20:59, 16 December 2023
Benzyl chloroformate (redirect from Z group)
early 1930s who used it for the introduction of the benzyloxycarbonyl protecting group, which became the basis of the Bergmann-Zervas carboxybenzyl method...
10 KB (920 words) - 21:29, 12 November 2023
chloroformate ester. It is used to introduce the fluorenylmethyloxycarbonyl protecting group as the Fmoc carbamate. This compound may be prepared by reacting 9-fluorenylmethanol...
2 KB (61 words) - 21:18, 28 November 2021
Diol (category Functional groups)
many subcategories have been identified. They are used as protecting groups of carbonyl groups, making them essential in synthesis of organic chemistry...
12 KB (1,284 words) - 19:59, 27 July 2024
Kocieński, Philip j. (1994). "3.2.2: Diol Protecting Groups—Acetals—Isopropylidene Acetals". Protecting Groups. Foundations of Organic Chemistry Series...
3 KB (331 words) - 13:50, 24 March 2024
with 2-cyanoethyl groups; The exocyclic amino groups in all nucleic bases except for T and U are protected with acyl protecting groups. To furnish a functional...
79 KB (9,462 words) - 18:31, 28 January 2024
C19H15Cl. It is an alkyl halide, sometimes used to introduce the trityl protecting group. Triphenylmethyl chloride is commercially available. It may be prepared...
4 KB (226 words) - 09:28, 31 October 2022
Skeletal formula (section Protecting groups)
the tosylate group A protecting group or protective group is introduced into a molecule by chemical modification of a functional group to obtain chemoselectivity...
28 KB (3,597 words) - 01:30, 6 July 2024
synthesised step-by-step in a single reaction vessel utilising selective protecting group chemistry. Benefits compared with normal synthesis in a liquid state...
12 KB (1,632 words) - 11:02, 14 August 2024
Chemical glycosylation (section Protecting groups)
non-participating group, a group usually without a carboxyl group, will often result in an α-glycoside. Below it can be seen that having an acetyl protecting group at...
16 KB (1,841 words) - 13:01, 31 July 2024
attached to certain functional groups in a reactant molecule, trimethylsilyl groups may also be used as temporary protecting groups during chemical synthesis...
9 KB (1,016 words) - 00:04, 19 July 2024
Tert-Butyldiphenylsilyl (category Protecting groups)
TBDPS, is a protecting group for alcohols. Its formula is C16H19Si-. The tert-butyldiphenylsilyl group was first suggested as a protecting group by Hanessian...
5 KB (582 words) - 23:47, 28 November 2023
succinimide protecting group, hydrolysis of the alkyl chloride using sodium hydroxide and protection of the free amine with a tert-butoxycarbonyl (Boc) group. The...
7 KB (526 words) - 15:48, 25 March 2024
sprinklers; see Glossary of firefighting equipment#P Pivaloyl protecting group (Piv), a protecting group in chemistry P = IV, the formula describing power in terms...
1 KB (189 words) - 12:16, 23 March 2024
2-Methoxyethoxymethyl chloride (category Protecting groups)
methoxyethoxy ether (MEM) protecting group. MEM protecting groups are generally preferred to methoxymethyl (MOM) protecting groups, both in terms of formation...
4 KB (282 words) - 10:19, 13 January 2024
reactions, all other functional groups present in nucleosides must be rendered unreactive (protected) by attaching protecting groups. Upon the completion of the...
25 KB (2,992 words) - 12:18, 16 January 2024
2,2,2-Trichloroethoxycarbonyl chloride (category Protecting groups)
(Troc) protecting group for amines, thiols and alcohols. It readily cleaves vs other carbamates and can be used in an overall protecting group strategy...
3 KB (141 words) - 05:09, 16 September 2023