• Thumbnail for Protein kinase B
    Protein kinase B (PKB), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple...
    35 KB (3,831 words) - 18:08, 20 August 2024
  • Thumbnail for Protein kinase A
    In cell biology, protein kinase A (PKA) is a family of serine-threonine kinase whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA...
    27 KB (2,665 words) - 17:03, 6 April 2024
  • In cell biology, protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling...
    27 KB (2,716 words) - 13:30, 2 November 2024
  • Thumbnail for Serine/threonine-specific protein kinase
    A serine/threonine protein kinase (EC 2.7.11.-) is a kinase enzyme, in particular a protein kinase, that phosphorylates the OH group of the amino-acid...
    14 KB (1,210 words) - 13:35, 14 June 2024
  • Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a dual-specificity kinase enzyme which phosphorylates mitogen-activated protein kinase (MAPK)...
    3 KB (296 words) - 17:06, 14 September 2023
  • Thumbnail for AMP-activated protein kinase
    5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular...
    65 KB (7,149 words) - 04:45, 26 August 2024
  • A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses...
    46 KB (5,492 words) - 05:56, 16 October 2024
  • biology, extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that...
    11 KB (1,128 words) - 03:46, 28 September 2024
  • Thumbnail for Phosphoinositide-dependent kinase-1
    In the field of biochemistry, PDPK1 refers to the protein 3-phosphoinositide-dependent protein kinase-1, an enzyme which is encoded by the PDPK1 gene in...
    18 KB (2,127 words) - 19:11, 8 April 2024
  • Thumbnail for Myotonin-protein kinase
    Myotonin-protein kinase (MT-PK) also known as myotonic dystrophy protein kinase (MDPK) or dystrophia myotonica protein kinase (DMPK) is an enzyme that...
    19 KB (2,426 words) - 16:47, 30 March 2024
  • Thumbnail for C-Jun N-terminal kinases
    transcriptional activation domain. They belong to the mitogen-activated protein kinase family, and are responsive to stress stimuli, such as cytokines, ultraviolet...
    14 KB (1,626 words) - 20:50, 30 May 2024
  • Activated Protein (MAP) kinase kinase kinase (MAPKKK, MKKK, M3K, or, MAP3K) is a serine/threonine-specific protein kinase which acts upon MAP kinase kinase. Subsequently...
    11 KB (1,345 words) - 09:11, 2 January 2024
  • Thumbnail for Phosphorylase kinase
    Phosphorylase kinase (PhK) is a serine/threonine-specific protein kinase which activates glycogen phosphorylase to release glucose-1-phosphate from glycogen...
    18 KB (2,153 words) - 16:07, 23 August 2024
  • Thumbnail for Ca2+/calmodulin-dependent protein kinase II
    Ca2+ /calmodulin-dependent protein kinase II (CaM kinase II or CaMKII) is a serine/threonine-specific protein kinase that is regulated by the Ca2+ /calmodulin...
    29 KB (3,458 words) - 01:05, 2 November 2024
  • Thumbnail for Tyrosine kinase
    A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to the tyrosine residues of specific proteins inside a cell. It functions as...
    43 KB (5,251 words) - 10:44, 24 June 2024
  • Thumbnail for Rho-associated protein kinase
    Rho-associated protein kinase (ROCK) is a kinase belonging to the AGC (PKA/ PKG/PKC) family of serine-threonine specific protein kinases. It is involved...
    19 KB (2,170 words) - 06:41, 27 May 2024
  • Thumbnail for CGMP-dependent protein kinase
    cGMP-dependent protein kinase or protein kinase G (PKG) is a serine/threonine-specific protein kinase that is activated by cGMP. It phosphorylates a number...
    8 KB (825 words) - 21:37, 20 April 2023
  • Thumbnail for Receptor tyrosine kinase
    unique tyrosine kinase genes identified in the human genome, 58 encode receptor tyrosine kinase proteins. Receptor tyrosine kinases have been shown not...
    28 KB (3,078 words) - 07:46, 3 June 2024
  • p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines...
    14 KB (1,385 words) - 10:32, 28 April 2024
  • Thumbnail for Bruton's tyrosine kinase
    Bruton's tyrosine kinase (abbreviated Btk or BTK), also known as tyrosine-protein kinase BTK, is a tyrosine kinase that is encoded by the BTK gene in humans...
    27 KB (2,837 words) - 12:09, 16 October 2024
  • Thumbnail for Tropomyosin receptor kinase B
    Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor,...
    39 KB (4,391 words) - 05:30, 23 October 2024
  • The IκB kinase enzyme complex is part of the upstream NF-κB signal transduction cascade. The IκBα (inhibitor of nuclear factor kappa B) protein inactivates...
    14 KB (1,447 words) - 09:31, 22 December 2023
  • Thumbnail for G protein-coupled receptor kinase
    G protein-coupled receptor kinases (GPCRKs, GRKs) are a family of protein kinases within the AGC (protein kinase A, protein kinase G, protein kinase C)...
    18 KB (2,053 words) - 10:12, 12 August 2024
  • Thumbnail for AKT1
    AKT1 (category Protein kinases)
    serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene. This enzyme belongs to the AKT subfamily of serine/threonine kinases that...
    24 KB (2,803 words) - 10:09, 29 October 2024
  • Thumbnail for BRAF (gene)
    BRAF (gene) (redirect from B-raf 1)
    the protein is more formally known as serine/threonine-protein kinase B-Raf. The B-Raf protein is involved in sending signals inside cells which are involved...
    48 KB (5,285 words) - 16:26, 21 August 2024
  • Thumbnail for Phosphoinositide 3-kinase
    identification of a previously unknown phosphoinositide kinase associated with the polyoma middle T protein. They observed unique substrate specificity and chromatographic...
    32 KB (3,463 words) - 17:34, 20 November 2023
  • A protein kinase inhibitor (PKI) is a type of enzyme inhibitor that blocks the action of one or more protein kinases. Protein kinases are enzymes that...
    23 KB (750 words) - 23:26, 13 August 2024
  • Thumbnail for Cyclin-dependent kinase
    Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression...
    35 KB (3,829 words) - 14:24, 17 June 2024
  • Thumbnail for Cyclin-dependent kinase 1
    Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine protein kinase...
    25 KB (2,896 words) - 12:38, 29 August 2024
  • Thumbnail for Protein phosphorylation
    by a protein kinase by the addition of a covalently bound phosphate group. Phosphorylation alters the structural conformation of a protein, causing it...
    67 KB (7,955 words) - 20:50, 29 July 2024