• Thumbnail for C-Raf
    C-Raf (redirect from RAF1)
    simply c-Raf or even Raf-1, is an enzyme that in humans is encoded by the RAF1 gene. The c-Raf protein is part of the ERK1/2 pathway as a MAP kinase (MAP3K)...
    69 KB (8,674 words) - 01:09, 28 March 2024
  • Thumbnail for Noonan syndrome
    of genetically diagnosed cases, SOS1 responsible for 10-13% of cases, and RAF1 or RIT1 - each contributing to an additional 5% of cases. Correlations between...
    41 KB (4,206 words) - 02:06, 14 September 2024
  • Frequencies Cuban Revolutionary Armed Forces C-Raf, a human enzyme encoded by the RAF1 gene This disambiguation page lists articles associated with the title CRAF...
    514 bytes (68 words) - 08:38, 2 February 2022
  • Re8 11.f4 Nd7 12.Qg4 Nxe5 13.Bxe5 Bf6 14.Rf3 Bxe5 15.fxe5 Qc7 16.Qh5 h6 17.Raf1 g6 18.Qxh6 Qxe5 19.Rf6 Qh5 20.Qxh5 gxh5 21.Nf3 Rc7 22.Rh6 f6 23.Nh4 Be8 24...
    14 KB (2,001 words) - 17:18, 26 October 2024
  • (aka TAO1 or TAOK1) MAP3K17 (aka TAO2 or TAOK2) MAP3K18 (aka TAO3 or TAOK3) RAF1 BRAF ARAF ZAK (aka MLTK) Several classes of MAPKKK exist, and all of them...
    11 KB (1,345 words) - 09:11, 2 January 2024
  • HRAS KRAS NRAS RRAS RIT1 NF1 RASA1 RASA2 SYNGAP1 SOS1 SOS2 CBL PTPN11 BRAF RAF1 MAP2K1 MAP2K2 MAP3K8 SPRED1 SPRY1 MYST4 LZTR1 A2ML1 Rauen KA (2022). "Defining...
    5 KB (470 words) - 11:25, 24 August 2024
  • Thumbnail for Melanoma
    oncogenic alterations include fusions involving various kinases such as BRAF, RAF1, ALK, RET, ROS1, NTRK1., NTRK3 and MET BRAF, RAS, and NF1 mutations and kinase...
    154 KB (16,086 words) - 21:51, 24 October 2024
  • recessive 1:60,000 Nonsyndromic deafness Noonan syndrome PTPN11, KRAS, SOS1, RAF1, NRAS, HRAS, BRAF, SHOC2, MAP2K1, MAP2K2, CBL dominant 1:1,000 Norman–Roberts...
    42 KB (983 words) - 18:14, 6 October 2024
  • pawn. 9... Kxf7 10. Qh5+ Kg7 11. Bxf4 Bxf4 12. Rxf4 Nf6 13. Qg5+ Kf7 14. Raf1 McDonnell has built up a winning attack almost effortlessly. 14... Ke8 15...
    9 KB (820 words) - 14:36, 1 August 2024
  • between TLR-dependent and TLR-independent signaling. DC-SIGN leading to RAF1-MEK-ERK cascade, BDCA2 signaling via ITAM and signaling through ITIM belong...
    43 KB (5,173 words) - 21:02, 10 August 2024
  • Thumbnail for World Chess Championship 2018
    9. 0-0 b6 10. Nh2 Nf8 11. f4 exf4 12. Rxf4 Be6 13. Rf2 h6 14. Qd2 g5 15. Raf1 Qd6 16. Ng4 0-0-0 17. Nf6 Nd7 18. Nh5 Be5 19. g4 f6 20. b3 Bf7 21. Nd1 Nf8...
    70 KB (7,521 words) - 10:49, 16 September 2024
  • the involvement of PA in cellular processes can be inferred. SK1 PDE4A1 Raf1 mTOR PP1 SHP1 Spo20p p47phox PKCε PLCβ PIP5K Opi1 TREK-1 Kv Kir2.2 Welti...
    25 KB (3,086 words) - 00:31, 3 December 2023
  • Thumbnail for AP-1 transcription factor
    PMID 15494506. Navas TA, Baldwin DT, Stewart TA (November 1999). "RIP2 is a Raf1-activated mitogen-activated protein kinase kinase". The Journal of Biological...
    41 KB (4,468 words) - 17:08, 21 September 2024
  • Thumbnail for RAP1A
    interference with Ras function interacts directly with Ras and competes with Raf1". Molecular and Cellular Biology. 15 (3): 1318–23. doi:10.1128/mcb.15.3.1318...
    6 KB (786 words) - 19:11, 3 December 2023
  • Thumbnail for BRAF (gene)
    BRAF Identifiers Aliases BRAF, B-RAF1, BRAF1, NS7, RAFB1, B-Raf, B-Raf proto-oncogene, serine/threonine kinase External IDs OMIM: 164757; MGI: 88190; HomoloGene:...
    48 KB (5,285 words) - 16:26, 21 August 2024
  • Bxf7+ Kxf7 9. Qh5+ Kg7 10. Rxf4 Nh6 11. Be3 d6 12. Ne2 Qe7 13. Kxg2 Be6 14. Raf1 Bf7? Black could have won with 14...Qg5+!!, when 15.Qxg5# would checkmate...
    71 KB (9,203 words) - 03:08, 10 July 2024
  • Thumbnail for World Chess Championship 1972
    Bg5 (diagram) 19. Bh5 cxd5 20. Bxf7+ Rxf7 21. Rxf7 Qd2 22. Qxd2 Bxd2 23. Raf1 Nc6 24. exd5 exd5 25. Rd7 Be3+ 26. Kh1 Bxd4 27. e6 Be5 28. Rxd5 Re8 29. Re1...
    100 KB (11,689 words) - 11:54, 9 August 2024
  • Thumbnail for Agustín Canapino
    Canapino Sports Chevrolet Coupé SS VIE 1512 NEU1 1610 CDU 338 SLU 135 ROS 74 RAF1 21 TRH 384 POS 362 CCD 43 SJV 3 RAF2 11 PAR 134 SNI 11 TOA 21 NEU2 44 1st...
    57 KB (1,536 words) - 01:16, 16 September 2024
  • Thumbnail for Sara García Alonso
    cancer in the laboratory of Mariano Barbacid. Her research has focused on RAF1 selective degraders as a therapeutic target, in order to combat certain forms...
    9 KB (674 words) - 21:05, 6 September 2024
  • Thumbnail for Eosinophil cationic protein
    RNASE3 Identifiers Aliases RNASE3, ECP, RNS3, RAF1, ribonuclease A family member 3 External IDs OMIM: 131398; MGI: 3528616; HomoloGene: 136763; GeneCards:...
    19 KB (2,337 words) - 23:05, 12 October 2024
  • Q8TD07 13367 RAET1G HGNC:16795 Q6H3X3 13368 RAET1L HGNC:16798 Q5VY80 13369 RAF1 HGNC:9829 P04049 13370 RAG1 HGNC:9831 P15918 13371 RAG2 HGNC:9832 P55895...
    282 KB (17 words) - 18:42, 6 October 2024
  • Thumbnail for YWHAG
    role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways...
    11 KB (1,363 words) - 20:29, 22 December 2023
  • Pos. Driver VIE NEU TOA1 ELC CDU TRH RAF1 POS VIL1 BUE SLU SNI RAF2 TOA2 VIL2 Total 1 Mariano Werner 11 42 4 108 511 2115 42 11 20 1013 21 122 11 156 41...
    74 KB (554 words) - 02:07, 27 October 2024
  • Thumbnail for MAP2K1
    Thomas D Y (Apr 1998). "Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases". J. Biol. Chem. 273 (17). UNITED STATES: 10475–84. doi:10...
    13 KB (1,478 words) - 04:12, 19 August 2024
  • Thumbnail for C1 domain
    PRKCG; PRKCH; PRKCI; PRKCN; PRKCQ; PRKCZ; PRKD1; PRKD2; PRKD3; RACGAP1; RAF1; RASGRP; RASGRP1; RASGRP2; RASGRP3; RASGRP4; RASSF1; RASSF5; ROCK1; ROCK2;...
    3 KB (321 words) - 23:35, 12 August 2023
  • Thumbnail for Occludin
    the cancer cells. Specifically, occludin has a strong inhibitory effect on Raf1-induced tumorigenesis. Still, the exact mechanism of how occludin prevents...
    24 KB (2,898 words) - 06:03, 10 June 2024
  • Thumbnail for CDC37
    complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK, as well as eIF-2 alpha kinases. It is thought to play a critical role...
    14 KB (1,482 words) - 16:33, 13 October 2024
  • pathways. Erk 1,2 can be stimulated through the activation cascades of K-Ras, Raf1, and MEK 1,2, whereas ERK5 is stimulated through the activation cascades...
    27 KB (3,122 words) - 21:45, 8 July 2024
  • related to Ras. Human proteins containing this domain include: ARAF BRAF RAF1 RGS12, RGS14 TIAM1 Ponting CP (October 1999). "Raf-like Ras/Rap-binding domains...
    1 KB (72 words) - 15:18, 1 October 2024
  • Thumbnail for Protein kinase domain
    PRKX ; PRKY ; PRPF4B ; PSKH1 ; PSKH2 ; PTK2 ; PTK2B ; PTK6 ; PTK7 ; PXK ; RAF1 ; RET ; RIOK1 ; RIOK2 ; RIOK3 ; RIPK1 ; RIPK2 ; RIPK3 ; RIPK4 ; RNASEL ;...
    17 KB (1,566 words) - 18:56, 22 September 2024