As well as activating GTPases (GEF), the same C9ORF72-SMCR8-WDR41 complex is proposed to inactivate GTPases, i.e. as a GTPase-activating protein (GAP)...
31 KB (3,542 words) - 21:42, 15 September 2024
regulator of the Ras oncogene signal transduction pathway. It stimulates the GTPase activity of Ras. In 1989, through linkage and cross over analyses, neurofibromin...
58 KB (6,734 words) - 22:47, 4 January 2025
Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases". PLOS Pathogens. 1 (3): e24. doi:10.1371/journal.ppat.0010024. PMC 1287907...
133 KB (14,741 words) - 01:27, 19 December 2024
CT scan of the head. Another example is KRAS, an oncogene that encodes a GTPase involved in several signal transduction pathways. Biomarkers for precision...
38 KB (4,436 words) - 06:28, 28 November 2024
PMID 15998911. Itoh T, Fukuda M (2006). "Identification of EPI64 as a GTPase-activating protein specific for Rab27A". J. Biol. Chem. 281 (42): 31823–31...
3 KB (432 words) - 07:00, 18 December 2023
"Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin". eLife. 2: e01279. doi:10.7554/eLife...
29 KB (3,556 words) - 15:09, 1 October 2024
regions for UDP-3-O-hydroxymyristoyl N-acetylglucosamine deacetylase and GTPAse cell division protein FtsZ. To the last group correspond the αr15CII loci...
119 KB (2,874 words) - 21:31, 28 March 2024