Rhizoxin is an antimitotic agent with anti-tumor activity. It is isolated from the fungus Rhizopus microsporus which causes rice seedling blight. Rhizoxin...
6 KB (518 words) - 09:44, 20 July 2024
endosymbiont Paraburkholderia rhizoxinica that produces the antitumor drug rhizoxin. Certain strains of Rhizopus microsporus use agricultural rice as a host...
15 KB (1,794 words) - 17:04, 10 January 2024
It inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site. It is a macrolide of the ansamycin type and can be isolated...
5 KB (286 words) - 22:19, 3 February 2024
oligosporus. R. microsporus produces several potentially toxic metabolites, rhizoxin and rhizonins A and B, but it appears the domestication and mutation of...
10 KB (1,104 words) - 18:46, 3 August 2024
it inhibits the assembly of microtubules by binding to tubulin (at the rhizoxin binding site). The monoclonal antibody binds specifically to a structure...
6 KB (471 words) - 09:43, 12 February 2024
found to produce rhizoxin, an inhibitor of mitosis originally thought to be produced by R. microsporus itself. The production of rhizoxin by Burkholderia...
8 KB (1,075 words) - 05:25, 10 February 2023
Epothilone A, the CD-Subunit of spongistatins, and the C10-C20 Subunit of rhizoxin A, The Keck allylation has also been utilized to form substituted tetrahydropyrans...
14 KB (1,612 words) - 14:31, 8 June 2024
antimicrobial compounds, for example, thailanstatin, spliceostatin, phytotoxin, rhizoxin, and others. Gladiolin was also discovered in another Burkholderia species...
7 KB (622 words) - 16:33, 1 March 2024
vector – retrovirus – RevM10 gene – rhabdoid tumor – rhabdomyosarcoma – rhizoxin – ribavirin – ribonucleotide reductase inhibitor – rifampin – risedronate...
69 KB (5,119 words) - 11:20, 3 June 2024
Stonehouse, Jeffery P. (2002). "A concise enantioselective total synthesis of rhizoxin D". Tetrahedron Lett. 43 (3): 493–497. doi:10.1016/S0040-4039(01)02154-2...
16 KB (1,734 words) - 08:59, 29 August 2023
Jaspamide and Geodiamolides and macrolides, namely Zearalenone, Rifamycin-S, Rhizoxin and Rapamycin. Rao is the pioneer of Chiral synthesis and technology in...
27 KB (2,224 words) - 17:48, 23 July 2024