Ryanodine receptor 1 (RYR-1) also known as skeletal muscle calcium release channel or skeletal muscle-type ryanodine receptor is one of a class of ryanodine...
11 KB (1,344 words) - 03:32, 4 September 2024
Ryanodine receptors (RyR for short) form a class of intracellular calcium channels in various forms of excitable animal tissue like muscles and neurons...
21 KB (2,355 words) - 13:40, 24 June 2024
Ryanodine receptor 2 (RYR2) is one of a class of ryanodine receptors and a protein found primarily in cardiac muscle. In humans, it is encoded by the RYR2...
16 KB (1,771 words) - 06:12, 25 September 2024
Ryanodine receptor 3 is one of a class of ryanodine receptors and a protein that in humans is encoded by the RYR3 gene. The protein encoded by this gene...
10 KB (962 words) - 22:42, 16 July 2024
Malignant hyperthermia (redirect from Malignant hyperthermia susceptibility type 1)
propensity for malignant hyperthermia is due to a mutation of the ryanodine receptor (type 1), located on the sarcoplasmic reticulum (SR), the organelle within...
45 KB (4,933 words) - 15:34, 26 July 2024
TRPV1 (redirect from Vanilloid receptor subtype 1)
transient receptor potential cation channel subfamily V member 1 (TRPV1), also known as the capsaicin receptor and the vanilloid receptor 1, is a protein...
57 KB (6,738 words) - 09:20, 7 August 2024
insecticide. The compound has extremely high affinity to the open-form ryanodine receptor, a group of calcium channels found in skeletal muscle, smooth muscle...
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identified as the ryanodine receptor 1 (RYR1) and the voltage-gated L-type calcium channel identified as dihydropyridine receptors, (DHPRs). DHPRs are...
62 KB (7,395 words) - 16:30, 12 July 2024
"Structural and functional conservation of key domains in InsP3 and ryanodine receptors". Nature. 483 (7387): 108–112. Bibcode:2012Natur.483..108S. doi:10...
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peptide (CPP); it binds with high affinity and specificity to skeletal ryanodine receptor 1 (RYR1) of the sarcoplasmic reticulum, thereby triggering calcium...
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stressors such as overwork or excitement. Caused by a mutated allele, ryanodine receptor 1 gene (RyR1) at nucleotide C7360G, generating a R2454G amino acid...
41 KB (4,572 words) - 00:50, 17 September 2024
Voltage-gated ion channel (redirect from Voltage-dependent anion channel 1)
including: inwardly rectifying K+ channels, ryanodine-inositol 1,4,5-triphosphate receptor Ca2+ channels, transient receptor potential Ca2+ channels, polycystin...
21 KB (2,298 words) - 12:09, 9 August 2024
Ligand-gated ion channel (redirect from Ionotropic receptor)
Voltage-dependent calcium channel Receptor (biochemistry) Inositol trisphosphate receptor Metabotropic receptor Ryanodine receptor "Gene Family: Ligand gated...
29 KB (2,597 words) - 03:43, 7 April 2024
of a group of short, basic peptides called calcins, which bind to ryanodine receptors (RyRs) and thereby trigger calcium release from the sarcoplasmic...
9 KB (1,129 words) - 18:50, 30 April 2024
release channel RYR1 (ryanodine receptor 1), and voltage-gated L-type calcium channels (identified as dihydropyridine receptors, DHPRs). DHPRs are located...
120 KB (13,834 words) - 22:03, 24 September 2024
Calcium channel (redirect from Receptor-operated calcium channel)
charged ions including calcium to pass through. These include P2X receptors, Transient Receptor Potential (TRP) channels, Cyclic nucleotide-gated (CNG) channels...
10 KB (760 words) - 22:20, 16 July 2024
Cav1.1 is a voltage-dependent calcium channel found in the transverse tubule of muscles. In skeletal muscle it associates with the ryanodine receptor RyR1...
13 KB (1,605 words) - 18:36, 22 August 2024
TRPM8 (redirect from Cold and menthol receptor 1)
Transient receptor potential cation channel subfamily M (melastatin) member 8 (TRPM8), also known as the cold and menthol receptor 1 (CMR1), is a protein...
27 KB (3,254 words) - 02:46, 17 September 2024
(1977) Local Anesthetics: Hydrophilic and Hydrophobic Pathways for the Drug-Receptor Reaction. The Journal of General Physiology, 69, 497-515. http://dx.doi...
34 KB (3,587 words) - 12:35, 24 June 2024
SR/terminal cisternae through a ryanodine receptor (RyR) and is known as a calcium spark. There are three types of ryanodine receptor, RyR1 (in skeletal muscle)...
13 KB (1,810 words) - 15:53, 11 May 2024
Membrane transport protein (section 1: Channels/pores)
Miller GM (January 2011). "The emerging role of trace amine-associated receptor 1 in the functional regulation of monoamine transporters and dopaminergic...
25 KB (2,646 words) - 00:12, 19 June 2024
Aquaporin 2 is regulated by vasopressin which, when bound to the cell-surface receptor, activates the cAMP signaling pathway. This results in aquaporin-2 containing...
38 KB (4,447 words) - 20:30, 21 August 2024
which encodes a protein included in an ion channel known as the ryanodine receptor; this channel releases calcium from a cell's internal calcium store...
42 KB (4,764 words) - 15:55, 4 January 2024
TRPA1 (redirect from TRPA1 receptor agonist)
Transient receptor potential cation channel, subfamily A, member 1, also known as transient receptor potential ankyrin 1, TRPA1, or The Wasabi Receptor, is...
35 KB (4,048 words) - 22:58, 16 July 2024
Transient receptor potential channels (TRP channels) are a group of ion channels located mostly on the plasma membrane of numerous animal cell types. Most...
49 KB (5,517 words) - 19:40, 16 September 2024
In biochemistry and pharmacology, receptors are chemical structures, composed of protein, that receive and transduce signals that may be integrated into...
26 KB (2,672 words) - 14:14, 22 July 2024
voltages. When vagally-released acetylcholine (ACh) binds to muscarinic M2 receptors, this promotes dissociation of βγ subunit complexes, leading to direct...
10 KB (1,195 words) - 21:33, 8 November 2023
which is mechanically gated to a calcium-release channel (a.k.a. ryanodine receptor, or RYR) in the sarcoplasmic reticulum (SR), causes opening of the...
28 KB (3,092 words) - 18:50, 27 October 2023
triggers calcium release from the sarcoplasmic reticulum by activating ryanodine receptor 2 (RyR2) (calcium-induced-calcium-release). Phosphorylation of these...
17 KB (2,004 words) - 01:57, 7 August 2024
(TRPC), vanilloid receptors (TRPV), melastatin (TRPM), polycystins (TRPP), mucolipins (TRPML), and ankyrin transmembrane protein 1 (TRPA). Hyperpolarization-activated...
44 KB (5,175 words) - 04:08, 10 September 2024