• Thumbnail for Ryanodine receptor 1
    Ryanodine receptor 1 (RYR-1) also known as skeletal muscle calcium release channel or skeletal muscle-type ryanodine receptor is one of a class of ryanodine...
    11 KB (1,344 words) - 03:32, 4 September 2024
  • Ryanodine receptors (RyR for short) form a class of intracellular calcium channels in various forms of excitable animal tissue like muscles and neurons...
    21 KB (2,355 words) - 13:40, 24 June 2024
  • Thumbnail for Ryanodine receptor 2
    Ryanodine receptor 2 (RYR2) is one of a class of ryanodine receptors and a protein found primarily in cardiac muscle. In humans, it is encoded by the RYR2...
    16 KB (1,771 words) - 06:12, 25 September 2024
  • Thumbnail for Ryanodine receptor 3
    Ryanodine receptor 3 is one of a class of ryanodine receptors and a protein that in humans is encoded by the RYR3 gene. The protein encoded by this gene...
    10 KB (962 words) - 22:42, 16 July 2024
  • Thumbnail for Malignant hyperthermia
    propensity for malignant hyperthermia is due to a mutation of the ryanodine receptor (type 1), located on the sarcoplasmic reticulum (SR), the organelle within...
    45 KB (4,933 words) - 15:34, 26 July 2024
  • Thumbnail for TRPV1
    transient receptor potential cation channel subfamily V member 1 (TRPV1), also known as the capsaicin receptor and the vanilloid receptor 1, is a protein...
    57 KB (6,738 words) - 09:20, 7 August 2024
  • Thumbnail for Ryanodine
    insecticide. The compound has extremely high affinity to the open-form ryanodine receptor, a group of calcium channels found in skeletal muscle, smooth muscle...
    4 KB (274 words) - 19:14, 7 June 2024
  • Thumbnail for Muscle contraction
    identified as the ryanodine receptor 1 (RYR1) and the voltage-gated L-type calcium channel identified as dihydropyridine receptors, (DHPRs). DHPRs are...
    62 KB (7,395 words) - 16:30, 12 July 2024
  • Thumbnail for Inositol trisphosphate receptor
    "Structural and functional conservation of key domains in InsP3 and ryanodine receptors". Nature. 483 (7387): 108–112. Bibcode:2012Natur.483..108S. doi:10...
    11 KB (1,115 words) - 13:40, 29 May 2024
  • Thumbnail for Vejocalcin
    peptide (CPP); it binds with high affinity and specificity to skeletal ryanodine receptor 1 (RYR1) of the sarcoplasmic reticulum, thereby triggering calcium...
    13 KB (1,437 words) - 04:49, 24 July 2024
  • Thumbnail for American Quarter Horse
    stressors such as overwork or excitement. Caused by a mutated allele, ryanodine receptor 1 gene (RyR1) at nucleotide C7360G, generating a R2454G amino acid...
    41 KB (4,572 words) - 00:50, 17 September 2024
  • Thumbnail for Voltage-gated ion channel
    including: inwardly rectifying K+ channels, ryanodine-inositol 1,4,5-triphosphate receptor Ca2+ channels, transient receptor potential Ca2+ channels, polycystin...
    21 KB (2,298 words) - 12:09, 9 August 2024
  • Thumbnail for Ligand-gated ion channel
    Voltage-dependent calcium channel Receptor (biochemistry) Inositol trisphosphate receptor Metabotropic receptor Ryanodine receptor "Gene Family: Ligand gated...
    29 KB (2,597 words) - 03:43, 7 April 2024
  • of a group of short, basic peptides called calcins, which bind to ryanodine receptors (RyRs) and thereby trigger calcium release from the sarcoplasmic...
    9 KB (1,129 words) - 18:50, 30 April 2024
  • Thumbnail for Skeletal muscle
    release channel RYR1 (ryanodine receptor 1), and voltage-gated L-type calcium channels (identified as dihydropyridine receptors, DHPRs). DHPRs are located...
    120 KB (13,834 words) - 22:03, 24 September 2024
  • charged ions including calcium to pass through. These include P2X receptors, Transient Receptor Potential (TRP) channels, Cyclic nucleotide-gated (CNG) channels...
    10 KB (760 words) - 22:20, 16 July 2024
  • Thumbnail for Cav1.1
    Cav1.1 is a voltage-dependent calcium channel found in the transverse tubule of muscles. In skeletal muscle it associates with the ryanodine receptor RyR1...
    13 KB (1,605 words) - 18:36, 22 August 2024
  • Thumbnail for TRPM8
    Transient receptor potential cation channel subfamily M (melastatin) member 8 (TRPM8), also known as the cold and menthol receptor 1 (CMR1), is a protein...
    27 KB (3,254 words) - 02:46, 17 September 2024
  • (1977) Local Anesthetics: Hydrophilic and Hydrophobic Pathways for the Drug-Receptor Reaction. The Journal of General Physiology, 69, 497-515. http://dx.doi...
    34 KB (3,587 words) - 12:35, 24 June 2024
  • Thumbnail for Sarcoplasmic reticulum
    SR/terminal cisternae through a ryanodine receptor (RyR) and is known as a calcium spark. There are three types of ryanodine receptor, RyR1 (in skeletal muscle)...
    13 KB (1,810 words) - 15:53, 11 May 2024
  • Miller GM (January 2011). "The emerging role of trace amine-associated receptor 1 in the functional regulation of monoamine transporters and dopaminergic...
    25 KB (2,646 words) - 00:12, 19 June 2024
  • Thumbnail for Aquaporin
    Aquaporin 2 is regulated by vasopressin which, when bound to the cell-surface receptor, activates the cAMP signaling pathway. This results in aquaporin-2 containing...
    38 KB (4,447 words) - 20:30, 21 August 2024
  • Thumbnail for Catecholaminergic polymorphic ventricular tachycardia
    which encodes a protein included in an ion channel known as the ryanodine receptor; this channel releases calcium from a cell's internal calcium store...
    42 KB (4,764 words) - 15:55, 4 January 2024
  • Thumbnail for TRPA1
    TRPA1 (redirect from TRPA1 receptor agonist)
    Transient receptor potential cation channel, subfamily A, member 1, also known as transient receptor potential ankyrin 1, TRPA1, or The Wasabi Receptor, is...
    35 KB (4,048 words) - 22:58, 16 July 2024
  • Transient receptor potential channels (TRP channels) are a group of ion channels located mostly on the plasma membrane of numerous animal cell types. Most...
    49 KB (5,517 words) - 19:40, 16 September 2024
  • Thumbnail for Receptor (biochemistry)
    In biochemistry and pharmacology, receptors are chemical structures, composed of protein, that receive and transduce signals that may be integrated into...
    26 KB (2,672 words) - 14:14, 22 July 2024
  • voltages. When vagally-released acetylcholine (ACh) binds to muscarinic M2 receptors, this promotes dissociation of βγ subunit complexes, leading to direct...
    10 KB (1,195 words) - 21:33, 8 November 2023
  • which is mechanically gated to a calcium-release channel (a.k.a. ryanodine receptor, or RYR) in the sarcoplasmic reticulum (SR), causes opening of the...
    28 KB (3,092 words) - 18:50, 27 October 2023
  • Thumbnail for L-type calcium channel
    triggers calcium release from the sarcoplasmic reticulum by activating ryanodine receptor 2 (RyR2) (calcium-induced-calcium-release). Phosphorylation of these...
    17 KB (2,004 words) - 01:57, 7 August 2024
  • Thumbnail for Ion channel
    (TRPC), vanilloid receptors (TRPV), melastatin (TRPM), polycystins (TRPP), mucolipins (TRPML), and ankyrin transmembrane protein 1 (TRPA). Hyperpolarization-activated...
    44 KB (5,175 words) - 04:08, 10 September 2024