protein 1 (pronounced spread-1) is a protein that in humans is encoded by the SPRED1 gene located on chromosome 15q13.2 and has seven coding exons. SPRED-1 is...
12 KB (1,498 words) - 12:21, 2 November 2024
mistaken for neurofibromatosis type I. It is caused by mutations in the SPRED1 gene. It is also known as neurofibromatosis type 1-like syndrome. Nearly...
9 KB (772 words) - 11:25, 24 August 2024
anemia is a risk factor for developing acute myeloid leukemia. Mutation in SPRED1 gene has been associated with a predisposition to childhood leukemia. Inherited...
83 KB (8,161 words) - 08:23, 11 November 2024
RASA1 RASA2 SYNGAP1 SOS1 SOS2 CBL PTPN11 BRAF RAF1 MAP2K1 MAP2K2 MAP3K8 SPRED1 SPRY1 MYST4 LZTR1 A2ML1 Rauen KA (2022). "Defining RASopathy". Disease Models...
5 KB (470 words) - 11:25, 24 August 2024
syndrome Splenic flexure syndrome Split hand syndrome Spondylo-ocular syndrome SPRED1 Staphylococcal scalded skin syndrome STAR syndrome Stauffer syndrome Stendhal...
42 KB (4,068 words) - 16:56, 1 November 2024
suppressor gene, thereby increasing the risk of T-ALL. Mutations in the SPRED1 gene are also associated with the development of T-ALL. Patients with immature...
24 KB (2,737 words) - 07:47, 28 September 2024
Q8IUH8 15731 SPPL3 HGNC:30424 Q8TCT6 15732 SPR HGNC:11257 P35270 15733 SPRED1 HGNC:20249 Q7Z699 15734 SPRED2 HGNC:17722 Q7Z698 15735 SPRED3 HGNC:31041...
242 KB (17 words) - 18:43, 6 October 2024
suggesting it represents a promising therapeutic target. Merlin (protein) SPRED1 gene GRCh38: Ensembl release 89: ENSG00000196712 – Ensembl, May 2017 GRCm38:...
49 KB (5,736 words) - 07:40, 25 October 2024
have enhanced inhibition. SPRY2 has been shown to interact with Cbl gene. SPRED1 gene Neurofibromin 1 SPRY1 GRCh38: Ensembl release 89: ENSG00000136158 –...
13 KB (1,541 words) - 20:32, 22 December 2023
ventricular noncompaction, X-linked; 300183; TAZ Legius syndrome; 611431; SPRED1 Leigh syndrome due to cytochrome c oxidase deficiency; 256000; COX15 Leigh...
234 KB (18,877 words) - 06:16, 6 November 2024
into treatments for both macular degeneration and Parkinson's disease. Spred1, a negative regulator of Ras-MAPK-ERK, is enriched in CNS germinal zones...
10 KB (1,025 words) - 16:35, 13 April 2024
proteins. Human genes encoding protein containing the SPR domain include: SPRED1, SPRED2, SPRED3, SPRY1, SPRY2, SPRY3, SPRY4 Zhang S, Lin Y, Itäranta P,...
4 KB (454 words) - 10:36, 3 December 2023
1016/j.bbrc.2006.10.150. PMID 17094949. GeneReviews/NIH/NCBI/UW entry on Legius syndrome SPRED1 Sprouty-related, EVH1 domain-containing protein 1 v t e...
5 KB (676 words) - 19:54, 3 March 2023
been predicted to interact with DR1, LRRCC1, FAM83F, TMEM256, Pdrm16 and SPRED1. LRRCC1 and TMEM256 were both mentioned with FAM98C as potentially novel...
15 KB (1,202 words) - 05:52, 27 March 2024
containing the WH1 (EVH1) domain include: ENAH, EVL HOMER1, HOMER2, HOMER3 SPRED1, SPRED2, SPRED3 VASP, WAS, WASL Symons M, Derry JM, Karlak B, Jiang S, Lemahieu...
8 KB (908 words) - 14:47, 19 October 2024
a protein that in humans is encoded by the SPRY1 gene. Neurofibromin 1 SPRED1 GRCh38: Ensembl release 89: ENSG00000164056 – Ensembl, May 2017 GRCm38:...
5 KB (632 words) - 03:49, 28 October 2022