A sarcomere (Greek σάρξ sarx "flesh", μέρος meros "part") is the smallest functional unit of striated muscle tissue. It is the repeating unit between...

which are in turn composed of myofibrils. Myofibrils are composed of sarcomeres, the basic building blocks of striated muscle tissue. Upon stimulation...

sarcomere length of cardiac muscle cells, in a resting ventricle, is lower than the optimal length for contraction. There is no bone to fix sarcomere...

Myomesin is a protein family found in the M-line of the sarcomere structure. Myomesin has various forms throughout the body in striated muscles with specialized...

the length of the myofibril in sections or units of contraction called sarcomeres. Muscles contract by sliding the thick myosin, and thin actin myofilaments...

tissue that features repeating functional units called sarcomeres. The presence of sarcomeres manifests as a series of bands visible along the muscle...

striated muscle tissues. It connects the Z disc to the M line in the sarcomere. The protein contributes to force transmission at the Z disc and resting...

proteins, particularly myosin, form structured filaments giving rise to sarcomere (a segment of muscle fibre). Their main aim was to use electron microscopy...

different components of the sarcomere. In normal muscle cells, the various parts of the muscle fibers that make up the sarcomere are distributed evenly in...

In cardiac physiology, preload is the amount of sarcomere stretch experienced by cardiac muscle cells, called cardiomyocytes, at the end of ventricular...

are enlarged. It is applied especially to the left ventricle of heart. Sarcomeres are added in series, as for example in dilated cardiomyopathy (in contrast...

Skeletal muscle cells and cardiac muscle cells both contain myofibrils and sarcomeres and form a striated muscle tissue. Cardiac muscle cells form the cardiac...

attributed to mutations in one of a number of genes that encode for the sarcomere proteins, and most diagnosed individuals will have an affected parent...

that the heart can work like a pump. They occur at the Z line of the sarcomere and can be visualized easily when observing a longitudinal section of...

in 1954. Physiologically, this contraction is not uniform across the sarcomere; the central position of the thick filaments becomes unstable and can...

myosin along the actin filaments causes the shortening and lengthening of the sarcomere; responsible for muscle contraction and relaxation, respectively....

holding onto a knife tightly. ATP is required to reuptake calcium into the sarcomere's sarcoplasmic reticulum (SR). When a muscle is relaxed, the myosin heads...

actin movement results in sarcomere shortening. Muscle contraction consists of the simultaneous shortening of multiple sarcomeres. The axon terminal of a...

striated – having a striped appearance due to the arrangement of the sarcomeres. A skeletal muscle contains multiple fascicles – bundles of muscle fibers...

structural-functional component of striated muscle cells which connects the sarcomere of the muscle to the cell membrane (i.e. the sarcolemma). Costameres are...

integrates the sarcolemma, Z disk, and nuclear membrane in sarcomeres and regulates sarcomere architecture. Desmin is a 53.5 kD protein composed of 470...

cannot contract anymore) Muscle soreness can stem from strain on the sarcomere, the muscle's functional unit, due to the mechanism of activation of the...

(59 °F), a phenomenon known as cold shortening occurs, whereby the muscle sarcomeres shrink to a third of their original length. Cold shortening is caused...

A-I junction; that is, the junction between the A and I bands of the sarcomere, which is the smallest unit of a muscle fiber. Triads form the anatomical...

myosin filaments and contain only the actin filaments of neighboring sarcomeres. Bisecting the I band and serving as an anchoring point for the two adjacent...

DOMS, these ruptures are microscopic lesions at the Z-line of the muscle sarcomere. The soreness has been attributed to the increased tension force and muscle...

non-genetic (acquired) origin. Genetic cardiomyopathies usually are caused by sarcomere or cytoskeletal diseases, neuromuscular disorders, inborn errors of metabolism...

(addition of sarcomere units parallel to existing units). Eccentric hypertrophy is related to volume overload and leads to the addition of sarcomeres in series...

bundles of myofibrils, which contain many contractile units known as sarcomeres, which give the tissue its striated (striped) appearance. Skeletal muscle...

organized into sarcomeres, the fundamental contractile units of muscle cells. The regular organization of myofibrils into sarcomeres gives cardiac muscle...