Scrapie (/ˈskreɪpi/) is a fatal, degenerative disease affecting the nervous systems of sheep and goats. It is one of several transmissible spongiform...

uncertain function. They are the hypothesized cause of various TSEs, including scrapie in sheep, chronic wasting disease (CWD) in deer, bovine spongiform encephalopathy...

with overlapping signs and symptoms. TSEs in non-human mammals include scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle – popularly...

either the remains of cattle who spontaneously developed the disease or scrapie-infected sheep products. The United Kingdom was afflicted with an outbreak...

protease-resistant form designated PrPRes such as the disease-causing PrPSc (scrapie) and an isoform located in mitochondria. The misfolded version PrPSc is...

astroglial hypertrophy in Scrapie, Kuru, Multiple Sclerosis and old age together with a note on the possible nature of the scrapie agent". Journal of Neurology...

is a hypothetical infectious particle once theorized to be the cause of scrapie and other degenerative diseases of the central nervous system. It was thought...

(TSEs), which include bovine spongiform encephalopathy (BSE) in cattle, scrapie in sheep and goats, and Creutzfeldt–Jakob disease (CJD) in humans. Bastian...

cow disease) in cattle, Creutzfeldt–Jakob disease (CJD) in humans, and scrapie in sheep. Natural infection causing CWD affects members of the deer family...

to study and develop scrapie-resistant sheep. An infectious, persistent, and spontaneous disease, animals infected with scrapie must be quarantined and...

In one-third of people with sporadic CJD, deposits of "prion protein (scrapie)", PrPSc, can be found in the skeletal muscle and/or the spleen. Diagnosis...

protein leading to a variety of spongiform encephalopathies such as kuru, scrapie and Creutzfeldt–Jakob disease. In Posthumanism in the Novels of Kurt Vonnegut...

among the first to find evidence indicating that the infectious agent in scrapie does not contain nucleic acid: a finding that was instrumental in understanding...

easily transmitted to pregnant women. Also of concern are the prion disease scrapie and the virus that causes foot-and-mouth disease (FMD), as both can devastate...

his 1998 PNAS review article on Prions, Prusiner wrote: "The idea that scrapie prions were composed of an amyloidogenic protein was truly heretical when...

susceptibility to specific TSE agent strains. Major agent strain distinctions from scrapie are encoded by different human TSE agents, such as sCJD, kuru of New Guinea...

clinical trial that attempted to eliminate scrapie from sheep by breeding out susceptibility to it. Scrapie can kill up to twenty-five percent of sheep...

hypersensitivity and inflammation. Hay mites are a suspected reservoir for scrapie, a prion disease of sheep. The mite Varroa destructor is a serious pest...

degenerative disease in humans. Kuru was shown to have remarkable similarity to scrapie, a disease of sheep and goats caused by an unconventional infectious agent...

the central nervous system in cattle. It is a fatal disease, similar to scrapie in sheep and goats, caused by a prion. A major epizootic affected the UK...

the possibility of transmission of scrapie, a deadly, degenerative prion disease of sheep and goats, though scrapie does not appear to be transmissible...

have spontaneously developed the disease as well as sheep infected with scrapie, a similar disease in sheep; the inclusion of brain and spinal cord tissue...

although other reports have shown no significant effect, and treatment of scrapie in mice and sheep has also shown no effect. Possible reasons for the lack...

conditions that may affect their health. Some, like classical swine fever and scrapie are specific to one population of animals, while others, like foot-and-mouth...

uncertain function. They are the hypothesized cause of various TSEs, including scrapie in sheep, chronic wasting disease (CWD) in deer, bovine spongiform encephalopathy...

inflammatory conditions, HIV-1 infection development, and neuroinvasive scrapie. Follicular DCs are a non-migratory population found in primary and secondary...

conditions that may affect their health. Some, like classical swine fever and scrapie are specific to one type of stock, while others, like foot-and-mouth disease...

to lead to the first reliable ante mortem screening test for vCJD, BSE, scrapie, CWD, and other transmissible spongiform encephalopathies. Given the technology's...

scab mite Psoroptes ovis, a psoroptid mite. Scabby mouth – see orf above. Scrapie – a wasting disease of sheep and goats, a transmissible spongiform encephalopathy...

that pentosan polysulfate could rapidly reduce the levels of abnormal (scrapie) prion without affecting the normal cellular isoform. As pentosan polysulfate...