Senescence (/sɪˈnɛsəns/) or biological aging is the gradual deterioration of functional characteristics in living organisms. Whole organism senescence...

Cellular senescence is a phenomenon characterized by the cessation of cell division. In their experiments during the early 1960s, Leonard Hayflick and...

Plant senescence is the process of aging in plants. Plants have both stress-induced and age-related developmental aging. Chlorophyll degradation during...

Negligible senescence is a term coined by biogerontologist Caleb Finch to denote organisms that do not exhibit evidence of biological aging (senescence), such...

This timeline lists notable events in the history of research into senescence or biological aging, including the research and development of life extension...

will divide between 40 and 60 times in cell culture before entering a senescence phase. This finding refuted the contention by Alexis Carrel that normal...

Senescence-associated beta-galactosidase (SA-β-gal or SABG) is a hypothetical hydrolase enzyme that catalyzes the hydrolysis of β-galactosides into monosaccharides...

Senescence-associated secretory phenotype (SASP) is a phenotype associated with senescent cells wherein those cells secrete high levels of inflammatory...

Lemaître, Jean-François (2016-11-07). "Comparative analyses of longevity and senescence reveal variable survival benefits of living in zoos across mammals". Scientific...

likely that cumulative damage to mitochondria is a significant cause of senescence, but not the single dominant cause.[citation needed] In 2005, de Grey...

bio-indefinite mortality) is a state in which the rate of mortality from senescence is stable or decreasing, thus decoupling it from chronological age. Various...

Bacterial senescence or bacterial aging refers to the gradual decrease in cellular function in individual bacteria as they increase in age. Indicators...

reproduction is suggestive of senescence in hydra: comment on Martinez, D., "Mortality patterns suggest lack of senescence in hydra." Exp Gerontol 33, 217–25"...

Strategies for engineered negligible senescence (SENS) is a range of proposed regenerative medical therapies, either planned or currently in development...

seen with increasing frequency with increasing senescence. They are essentially complications of senescence, distinguished from the aging process itself...

The societal effects of negligible senescence considers a scenario where negligible senescence is achieved on a societal wide level in humans. There is...

protects against cancer while increasing the risks associated with cellular senescence. p16 is an inhibitor of cyclin-dependent kinases (CDK). It slows down...

50 years of age have not been determined. A senolytic (from the words senescence and -lytic, "destroying") is among a class of small molecules under basic...

1935 that ethylene acts similar to auxins in causing plant growth and senescence of vegetative tissues. This established that ethylene is a plant hormone...

the process of cellular senescence, which is related to, and yet distinct from, organismal aging. Replicative cellular senescence refers to a permanent...

proteostasis, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication." Oxidation...

been shown to cause bridging fibrosis in experimental animal models. Senescence of hepatic stellate cells could prevent progression of liver fibrosis...

A senolytic (from the words senescence and -lytic, "destroying") is among a class of small molecules under basic research to determine if they can selectively...

all living organisms experience a gradual and irreversible increase in senescence and an associated loss of proper function of the bodily systems. As aging...

concentration. Pathophysiology of the fetal membranes, such as microfractures, senescence of cells in the fetal membrane and inflammation can lead to an increased...

Red blood cells (RBCs), referred to as erythrocytes (from Ancient Greek erythros 'red' and kytos 'hollow vessel', with -cyte translated as 'cell' in modern...

biological aging, known in life sciences as "senescence." Some organisms experience negligible senescence, even exhibiting biological immortality. These...

do the mutants with a damaged regulatory system. The process of plant senescence involves the degradation of chlorophyll: for example the enzyme chlorophyllase...

associated with telomere length and represent potential markers of a decreased senescence in vivo". Cancer Epidemiology, Biomarkers & Prevention. 16 (7): 1499–1502...

Biotechnology Computing Palaeontology Quantum computing and communication Senescence research Sustainable energy research Environment Birding and ornithology...