• Thumbnail for Sialidase-4
    Sialidase-4 is an enzyme that in humans is encoded by the NEU4 gene. This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid...
    4 KB (472 words) - 19:54, 3 March 2023
  • Thumbnail for Neuraminidase
    Exo-α-sialidase (EC 3.2.1.18, sialidase, neuraminidase; systematic name acetylneuraminyl hydrolase) is a glycoside hydrolase that cleaves the glycosidic...
    16 KB (1,568 words) - 17:03, 31 May 2024
  • Thumbnail for Sialidase-1
    Sialidase-1, is a mammalian lysosomal neuraminidase enzyme which in humans is encoded by the NEU1 gene. The protein SIALIDASE-1 encoded by the NEU-1 gene...
    10 KB (1,234 words) - 03:35, 6 May 2024
  • β-D-fucosidase α-galactosidase β-glucuronidase pyrrolidonylarylamidase sialidase Normally found in infections of the human throat, patients with pharyngitis...
    7 KB (712 words) - 21:42, 18 December 2023
  • Thumbnail for Sialidase-2
    Sialidase-2 is an enzyme that in humans is encoded by the NEU2 gene. This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid...
    6 KB (664 words) - 16:33, 27 January 2024
  • Thumbnail for Sialidase-3
    Sialidase-3 is an enzyme that in humans is encoded by the NEU3 gene. This gene product belongs to a family of glycohydrolytic enzymes which remove sialic...
    9 KB (1,122 words) - 22:20, 5 January 2024
  • Thumbnail for Sialidosis
    results from a deficiency of the enzyme alpha-N -acetyl neuraminidase (sialidase). The lack of this enzyme results in an abnormal accumulation of complex...
    5 KB (539 words) - 22:08, 9 September 2024
  • Thumbnail for Clostridium perfringens
    include: Sialidase, Hexosaminidase, Galactosidase, Fucosidase, and Complementary enzymes belonging to various glycoside hydrolase families. Sialidases, also...
    61 KB (6,856 words) - 18:04, 26 October 2024
  • "Turnover Is Rate-Limited by Deglycosylation for Micromonospora viridifaciens Sialidase-Catalyzed Hydrolyses: Conformational Implications for the Michaelis Complex"...
    4 KB (396 words) - 01:04, 2 September 2023
  • Kok GB, Pegg MS, Dyason JC, Jin B, et al. Rational design of potent sialidase-based inhibitors of influenza virus replication. Nature. 1993 Jun 3;363(6428):418–423...
    21 KB (2,372 words) - 06:44, 3 November 2024
  • Thumbnail for Akkermansia muciniphila
    sugars from the end of the mucin O-glycan chain with fucosidases and sialidases, respectively. A. muciniphila can then get access to the de-capped O-glycans...
    13 KB (1,245 words) - 14:08, 12 August 2024
  • Thumbnail for Glycoside hydrolase family 33
    synthetic substrates. Sialidases may act as pathogenic factors in microbial infections. The 1.8 A structure of trans-sialidase from leech (Macrobdella...
    5 KB (473 words) - 21:19, 6 August 2023
  • Thumbnail for Axon
    receptors. The ganglioside-converting enzyme plasma membrane ganglioside sialidase (PMGS), which is involved in the activation of TrkA at the tip of neutrites...
    59 KB (6,983 words) - 23:19, 1 November 2024
  • Thumbnail for Lectin
    PMID 5055944. Ellen, R.P.; Fillery, E.D.; Chan, K.H.; Grove, D.A. (1980). "Sialidase-Enhanced Lectin-Like Mechanism for Actinomyces viscosus and Actinomyces...
    30 KB (3,038 words) - 13:30, 24 October 2024
  • Thumbnail for N-Glycolylneuraminic acid
    entered the cell via pinocytosis, the molecule is released by lysosomal sialidase. The molecule is then transferred into the cytosol by the lysosomal sialic...
    14 KB (1,474 words) - 09:57, 10 May 2024
  • Thumbnail for Tay–Sachs disease
    substrate accumulation. One experiment has demonstrated that using the enzyme sialidase allows the genetic defect to be effectively bypassed, and as a consequence...
    58 KB (6,401 words) - 02:47, 22 September 2024
  • Thumbnail for Murine respirovirus
    with sialidase improves activation of NK cell secretion of IFN-γ. Some paramyxoviruses, including SeV encode and synthesize neuraminidase (sialidase), which...
    296 KB (31,942 words) - 21:22, 28 August 2024
  • Thumbnail for Aerobic vaginitis
    G.G.; Bellen, G.; Brown, D.R.; Parada, C.M.G.L.; Silva, M.G. (2013). "Sialidase activity in aerobic vaginitis is equal to levels during bacterial vaginosis"...
    14 KB (1,403 words) - 03:13, 2 November 2024
  • Thumbnail for Zanamivir
    MS, Dyason JC, Jin B, et al. (June 1993). "Rational design of potent sialidase-based inhibitors of influenza virus replication". Nature. 363 (6428):...
    19 KB (1,929 words) - 13:03, 22 July 2024
  • Thumbnail for PTX3
    internalization of zymosan by macrophages". Journal of Leukocyte Biology. 75 (4): 649–56. doi:10.1189/jlb.0803371. PMID 14726497. S2CID 1172342. Bottazzi...
    21 KB (2,700 words) - 15:01, 9 May 2024
  • Thumbnail for Streptococcus oralis
    K.A.; Beighton, D. (2000-03-01). "Isolation and characterisation of sialidase from a strain of Streptococcus oralis". Journal of Medical Microbiology...
    14 KB (1,350 words) - 22:11, 11 July 2024
  • Thumbnail for Southern Kaduna
    Prize and (2013); discovered the gene responsible for the synthesis of sialidase Patrick Ibrahim Yakowa (1948–2012), 1st Governor of Kaduna State from...
    35 KB (2,372 words) - 11:17, 21 September 2024
  • polygalacturonase EC 3.2.1.16: deleted EC 3.2.1.17: lysozyme EC 3.2.1.18: exo-α-sialidase EC 3.2.1.19: deleted EC 3.2.1.20: α-glucosidase EC 3.2.1.21: β-glucosidase...
    119 KB (15,555 words) - 06:24, 19 September 2024
  • ; Zheng, Pan; Liu, Yang (2011). "Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction". Nature Biotechnology...
    9 KB (851 words) - 04:29, 12 August 2024
  • micrometres. Staining Procedure Digest using a diastase, hyaluronidase, or sialidase procedure Deparaffinize and hydrate to distilled water Oxidize in Periodic...
    11 KB (1,662 words) - 15:52, 9 May 2024
  • Mucolipidosis type IV (ML IV, ganglioside sialidase deficiency, or ML4) is an autosomal recessive lysosomal storage disorder. Individuals with the disorder...
    9 KB (946 words) - 15:03, 27 October 2023
  • Thumbnail for GLB1
    A, Pshezhetsky AV, von Itzstein M, Starcher B (Feb 2006). "Lysosomal sialidase (neuraminidase-1) is targeted to the cell surface in a multiprotein complex...
    16 KB (1,882 words) - 11:53, 16 May 2024
  • to be secreted: 54 glycoside hydrolases, one glycosyl hydrolase, seven sialidases, and three sulfatases. The PytT genome is predicted to encode a cytochrome...
    7 KB (757 words) - 06:15, 3 June 2024
  • Neuraminidase inhibitors inhibit enzymatic activity of the enzyme neuraminidase (sialidase). These type of inhibitors have been introduced as anti-influenza drugs...
    30 KB (4,066 words) - 17:50, 28 January 2023
  • Thumbnail for Viral neuraminidase
    family 34 CAZY GH_34 which comprises enzymes with only one known activity; sialidase or neuraminidase EC 3.2.1.18. Neuraminidases cleave the terminal sialic...
    11 KB (1,059 words) - 09:11, 30 January 2024