The signal recognition particle (SRP) is an abundant, cytosolic, universally conserved ribonucleoprotein (protein-RNA complex) that recognizes and targets...
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Signal-recognition-particle GTPase (EC 3.6.5.4) is an enzyme with systematic name GTP phosphohydrolase (protein-synthesis-assisting). This enzyme catalyses...
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large monomeric GTPases. Much of the SIMIBI class of GTPases is activated by dimerization. Named after the signal recognition particle (SRP), MinD, and...
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The signal recognition particle RNA, (also known as 7SL, 6S, ffs, or 4.5S RNA) is part of the signal recognition particle (SRP) ribonucleoprotein complex...
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Signal recognition particle (SRP) receptor, also called the docking protein, is a dimer composed of 2 different subunits that are associated exclusively...
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which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors...
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Protein targeting (redirect from Protein sorting signals)
being synthesized on the ribosome, when a signal recognition particle (SRP) recognizes an N-terminal signal peptide of the nascent protein. Binding of...
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(1991). "Requirement of GTP hydrolysis for dissociation of the signal recognition particle from its receptor". Science. 252 (5009): 1171–1173. Bibcode:1991Sci...
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significant membrane protrusions, but the downstream signalling of both pathways converge to activate Rho GTPases. They control actin polymerisation which is required...
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importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene...
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G-protein GTPase EC 3.6.5.2: small monomeric GTPase EC 3.6.5.3: protein-synthesizing GTPase EC 3.6.5.4: signal-recognition-particle GTPase EC 3.6.5.5:...
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of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting...
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importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene...
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Selenomethionine Selenoprotein Serine Serine kinase Serotonin Skatole Signal recognition particle Somatostatin Sorbic acid Sphingolipid Sphingosine Squalene Staurosporin...
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structure of the mRNA, from which the 43S particle scans 5'-->3' along the mRNA to reach an AUG start codon. Recognition of the start codon by the Met-tRNAiMet...
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reproduction - SH3 domain - SI - sigma factor - signal peptide - signal recognition particle - signal sequence - signal transduction - sincalide - skeleton - skin...
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dendritic cells. Pyrin particularly detects the inactivation of the Rho GTPase RHOA by bacterial factors. Upon RHOA inactivation, pyrin engages in a homotypic...
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Reelin (section Signaling cascades)
of reeler. Pinpointing the DAB1 as a pivotal regulator of the reelin signaling cascade started the tedious process of deciphering its complex interactions...
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encoding protein Spastic paraplegia 14 (autosomal recessive) SRPRB: Signal recognition particle receptor subunit beta TEX55: encoding protein Testis expressed...
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O; Mielke, T; Pool, MR; Sinning, I; Beckmann, R (May 2006). "Signal recognition particle receptor exposes the ribosomal translocon binding site". Science...
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Protein (section Cell signaling and ligand binding)
2009). "Regulation of epithelial apical junctional complex by Rho family GTPases". Frontiers in Bioscience. 14 (3): 1129–1142. doi:10.2741/3298. PMID 19273120...
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mechanism requiring the activation Src-family kinases, JNK and Rho-family GTPases. Unlike macropinocytosis this process is not affected by inhibitors of...
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is also activated by the small GTPase Cdc42, while another nucleation promoting factor WAVE is activated by the GTPase Rac1. Although most yeasts have...
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facilitated by elongation factor-Tu (EF-Tu), a small GTPase. For fast and accurate recognition of the appropriate tRNA, the ribosome utilizes large conformational...
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protein recognition. Rabin8 is a guanine nucleotide exchange factor for Rab8 necessary for ciliogenesis in primary cilia. Rab family GTPases usually assist...
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MA, Schaller MD, Ginsberg MH (1995). "Integrins: emerging paradigms of signal transduction". Annual Review of Cell and Developmental Biology. 11: 549–99...
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head. Another example is KRAS, an oncogene that encodes a GTPase involved in several signal transduction pathways. Biomarkers for precision oncology are...
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PR (Nov 1998). "A structural explanation for the recognition of tyrosine-based endocytotic signals". Science. 282 (5392): 1327–32. Bibcode:1998Sci.....
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protein is 632 amino acids long. It has 19 exons and two polyadenylation signals. Its sequence only partially matches a Kozak consensus sequence. The predicted...
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containing domain 9 is involved in death signaling of malignant glioma treated with inactivated Sendai virus particle (HVJ-E) or type I interferon". International...
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