• The signal recognition particle (SRP) is an abundant, cytosolic, universally conserved ribonucleoprotein (protein-RNA complex) that recognizes and targets...
    13 KB (1,203 words) - 22:07, 23 April 2024
  • Signal-recognition-particle GTPase (EC 3.6.5.4) is an enzyme with systematic name GTP phosphohydrolase (protein-synthesis-assisting). This enzyme catalyses...
    2 KB (209 words) - 15:49, 26 August 2023
  • large monomeric GTPases. Much of the SIMIBI class of GTPases is activated by dimerization. Named after the signal recognition particle (SRP), MinD, and...
    20 KB (2,306 words) - 18:17, 15 July 2024
  • Thumbnail for Signal recognition particle RNA
    The signal recognition particle RNA, (also known as 7SL, 6S, ffs, or 4.5S RNA) is part of the signal recognition particle (SRP) ribonucleoprotein complex...
    33 KB (3,765 words) - 06:29, 6 May 2024
  • Thumbnail for Signal recognition particle receptor
    Signal recognition particle (SRP) receptor, also called the docking protein, is a dimer composed of 2 different subunits that are associated exclusively...
    7 KB (831 words) - 08:12, 28 June 2024
  • Thumbnail for SRPRB
    which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors...
    5 KB (612 words) - 13:24, 7 September 2023
  • being synthesized on the ribosome, when a signal recognition particle (SRP) recognizes an N-terminal signal peptide of the nascent protein. Binding of...
    53 KB (6,404 words) - 17:09, 30 September 2024
  • Thumbnail for 5'-Guanylyl imidodiphosphate
    (1991). "Requirement of GTP hydrolysis for dissociation of the signal recognition particle from its receptor". Science. 252 (5009): 1171–1173. Bibcode:1991Sci...
    3 KB (165 words) - 12:49, 14 January 2024
  • Thumbnail for Phagosome
    significant membrane protrusions, but the downstream signalling of both pathways converge to activate Rho GTPases. They control actin polymerisation which is required...
    28 KB (3,339 words) - 09:21, 2 July 2024
  • Thumbnail for IPO8
    importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene...
    4 KB (604 words) - 11:03, 3 December 2023
  • G-protein GTPase EC 3.6.5.2: small monomeric GTPase EC 3.6.5.3: protein-synthesizing GTPase EC 3.6.5.4: signal-recognition-particle GTPase EC 3.6.5.5:...
    119 KB (15,555 words) - 06:24, 19 September 2024
  • Thumbnail for Srp receptor alpha subunit
    of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting...
    904 bytes (138 words) - 11:23, 17 October 2022
  • Thumbnail for IPO7
    importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene...
    8 KB (943 words) - 03:49, 27 January 2024
  • Selenomethionine Selenoprotein Serine Serine kinase Serotonin Skatole Signal recognition particle Somatostatin Sorbic acid Sphingolipid Sphingosine Squalene Staurosporin...
    12 KB (933 words) - 20:02, 10 May 2023
  • structure of the mRNA, from which the 43S particle scans 5'-->3' along the mRNA to reach an AUG start codon. Recognition of the start codon by the Met-tRNAiMet...
    13 KB (1,595 words) - 17:00, 27 August 2024
  • Thumbnail for Index of biochemistry articles
    reproduction - SH3 domain - SI - sigma factor - signal peptide - signal recognition particle - signal sequence - signal transduction - sincalide - skeleton - skin...
    29 KB (2,471 words) - 04:50, 19 January 2024
  • dendritic cells. Pyrin particularly detects the inactivation of the Rho GTPase RHOA by bacterial factors. Upon RHOA inactivation, pyrin engages in a homotypic...
    71 KB (7,823 words) - 11:34, 29 July 2024
  • Thumbnail for Reelin
    of reeler. Pinpointing the DAB1 as a pivotal regulator of the reelin signaling cascade started the tedious process of deciphering its complex interactions...
    140 KB (15,028 words) - 06:28, 5 August 2024
  • Thumbnail for Chromosome 3
    encoding protein Spastic paraplegia 14 (autosomal recessive) SRPRB: Signal recognition particle receptor subunit beta TEX55: encoding protein Testis expressed...
    34 KB (1,982 words) - 21:02, 24 August 2024
  • Thumbnail for Eukaryotic ribosome
    O; Mielke, T; Pool, MR; Sinning, I; Beckmann, R (May 2006). "Signal recognition particle receptor exposes the ribosomal translocon binding site". Science...
    40 KB (3,977 words) - 01:19, 21 April 2024
  • Thumbnail for Protein
    2009). "Regulation of epithelial apical junctional complex by Rho family GTPases". Frontiers in Bioscience. 14 (3): 1129–1142. doi:10.2741/3298. PMID 19273120...
    102 KB (11,386 words) - 22:54, 1 October 2024
  • Thumbnail for CD36
    mechanism requiring the activation Src-family kinases, JNK and Rho-family GTPases. Unlike macropinocytosis this process is not affected by inhibitors of...
    44 KB (5,085 words) - 19:02, 7 June 2024
  • Thumbnail for Actin
    is also activated by the small GTPase Cdc42, while another nucleation promoting factor WAVE is activated by the GTPase Rac1. Although most yeasts have...
    153 KB (18,278 words) - 03:30, 28 September 2024
  • facilitated by elongation factor-Tu (EF-Tu), a small GTPase. For fast and accurate recognition of the appropriate tRNA, the ribosome utilizes large conformational...
    23 KB (2,920 words) - 19:50, 17 August 2024
  • protein recognition. Rabin8 is a guanine nucleotide exchange factor for Rab8 necessary for ciliogenesis in primary cilia. Rab family GTPases usually assist...
    53 KB (6,700 words) - 03:20, 27 July 2024
  • Thumbnail for Integrin beta 1
    MA, Schaller MD, Ginsberg MH (1995). "Integrins: emerging paradigms of signal transduction". Annual Review of Cell and Developmental Biology. 11: 549–99...
    22 KB (2,600 words) - 22:18, 2 April 2024
  • head. Another example is KRAS, an oncogene that encodes a GTPase involved in several signal transduction pathways. Biomarkers for precision oncology are...
    38 KB (4,442 words) - 03:39, 7 August 2024
  • Thumbnail for AP2M1
    PR (Nov 1998). "A structural explanation for the recognition of tyrosine-based endocytotic signals". Science. 282 (5392): 1327–32. Bibcode:1998Sci.....
    10 KB (1,313 words) - 06:14, 1 January 2024
  • Thumbnail for GOLGA8H
    protein is 632 amino acids long. It has 19 exons and two polyadenylation signals. Its sequence only partially matches a Kozak consensus sequence. The predicted...
    17 KB (1,370 words) - 09:44, 11 August 2024
  • Thumbnail for Murine respirovirus
    containing domain 9 is involved in death signaling of malignant glioma treated with inactivated Sendai virus particle (HVJ-E) or type I interferon". International...
    296 KB (31,942 words) - 21:22, 28 August 2024