The stepwise mutation model (SMM) is a mathematical theory, developed by Motoo Kimura and Tomoko Ohta, that allows for investigation of the equilibrium...
8 KB (1,047 words) - 22:25, 3 December 2023
number of available peptide and genetic sequences. The stepwise mutation model is a "ladder model" that can be applied to electrophoresis studies where...
17 KB (1,607 words) - 13:19, 23 July 2024
microsatellite markers and is based on the stepwise-mutation model (SMM). The Goldstein distance formula is modeled in such a way that expected value will...
39 KB (4,749 words) - 04:22, 4 August 2024
Conference Solar Maximum Mission or SolarMax, an artificial satellite Stepwise mutation model, of allelic frequencies Smouldering Multiple Myeloma Scattering-matrix...
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Nebel, A; et al. (2001). "Haplogroup-specific deviation from the stepwise mutation model at the microsatellite loci DYS388 and DYS392". Eur J Hum Genet...
66 KB (6,377 words) - 19:12, 22 August 2024
development of the two main mutation models in population genetics: the infinite alleles model and the stepwise mutation model. Ranajit Chakraborty made...
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Institution of Washington Yearbook 75: 456-459 Evaluation of the stepwise mutation model of electrophoretic mobility: Comparison of the gel sieving behavior...
11 KB (1,312 words) - 01:50, 20 June 2024
Carcinogenesis (section Multiple mutations)
the prevailing accepted theory of carcinogenesis, the somatic mutation theory, mutations in DNA and epimutations that lead to cancer disrupt these orderly...
115 KB (13,937 words) - 12:31, 12 July 2024
Nonsense-mediated decay (section Mutations)
of mRNAs that are transcribed from alleles carrying nonsense mutations. Nonsense mutations code for a premature stop codon which causes the protein to...
23 KB (2,900 words) - 08:39, 17 August 2024
Helicase (section ATRX helicase mutations)
conditions that arise from mutations in human RecQ helicases. RecQ helicase Sgs1 is missing in yeast cells, making them useful models for comprehending human...
56 KB (6,916 words) - 19:33, 23 July 2024
ANNOVAR (section Using ANNOVAR for prioritization of genetic variants to identify mutations in a rare genetic disease)
annotations could be used to determine the functional consequences of the mutations on the genes and organisms, infer cytogenetic bands, report functional...
30 KB (3,454 words) - 04:02, 12 December 2023
Helitron (biology) (section The concerted model)
occurs simultaneously while in the sequential model they occur in a stepwise fashion. The concerted model does not require a circular intermediate although...
28 KB (3,784 words) - 18:50, 27 August 2023
Retrieved 2023-10-25. Canty-Laird EG, Lu Y, Kadler KE (January 2012). "Stepwise proteolytic activation of type I procollagen to collagen within the secretory...
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Viral phylodynamics (section Compartmental models)
year to influence transmission rate in a stepwise or sinusoidal fashion. To connect the epidemiological model to viral genealogies requires that multiple...
86 KB (11,392 words) - 09:41, 26 June 2024
induced pluripotent stem cell models and CRISPR/Cas9-produced mouse models in his lab to explore the pathogenesis of mutations in those specific genes. His...
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the constraints of the binding pocket by assembling small pieces in a stepwise manner. These pieces can be either individual atoms or molecular fragments...
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differentiation of spermatogonia into mature germ cells that progress stepwise through the long process of spermatogenesis, ending in the release of spermatozoa...
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mammals it occurs in the seminiferous tubules of the male testes in a stepwise fashion. Spermatogenesis is highly dependent upon optimal conditions for...
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procedure, a stepwise algorithm for controlling the FWER that is at least as powerful as the well-known Bonferroni adjustment. This stepwise algorithm sorts...
32 KB (4,513 words) - 02:54, 9 June 2024
nitrification, the stepwise oxidation of ammonia (NH 3) to nitrite (NO− 2) and to nitrate (NO− 3) anaerobic heterotrophic denitrification, the stepwise reduction...
96 KB (10,049 words) - 21:10, 21 August 2024
Feature selection (category Model selection)
traditional regression analysis, the most popular form of feature selection is stepwise regression, which is a wrapper technique. It is a greedy algorithm that...
58 KB (6,933 words) - 03:15, 11 March 2024
step-and-shoot CT, is a type of scanning method in which the CT table moves stepwise. The table increments to a particular location and then stops which is...
153 KB (15,964 words) - 17:36, 10 July 2024
Distyly (section Models of evolution)
Similar to other S-loci, the Nymphoides S-locus appears to have evolved via stepwise duplication events. In Primula the S-locus is composed of five genes, CYPT(or...
27 KB (2,985 words) - 04:09, 19 June 2024
000–40,000 years ago, the use of stone tools seems to have progressed stepwise. Each phase (H. habilis, H. ergaster, H. neanderthalensis) marked a new...
265 KB (26,530 words) - 09:59, 21 August 2024
by a sequence of reactions that by-pass free sugars and assemble in a stepwise fashion by including nitrogenous and oxygenous chemistries. In a series...
92 KB (10,692 words) - 14:18, 22 July 2024
regression Ordinary least squares regression (OLSR) Linear regression Stepwise regression Multivariate adaptive regression splines (MARS) Regularization...
41 KB (3,580 words) - 16:15, 14 June 2024
Institute. Retrieved 2015-04-05. Renyi Liu; Ochman, Howard (April 24, 2007). "Stepwise formation of the bacterial flagellar system". Proc. Natl. Acad. Sci. U...
169 KB (17,385 words) - 17:27, 20 August 2024
convergent evolution from comparative data by fitting Ornstein-Uhlenbeck models with stepwise Akaike Information Criterion". Methods in Ecology and Evolution....
57 KB (5,739 words) - 13:49, 18 August 2024
Jiménez-Delgado, S.; Technau, U.; Roy, S.; Marfany, G.; Garcia-Fernàndez, J. (2011). Stepwise assembly of the nova-regulated alternative splicing network in the vertebrate...
10 KB (1,084 words) - 04:54, 10 February 2024
"The mechanism of dienoyl-CoA reduction by 2,4-dienoyl-CoA reductase is stepwise: observation of a dienolate intermediate". Biochemistry. 40 (41): 12412–12421...
15 KB (1,747 words) - 17:11, 11 December 2023