• Thumbnail for Toll-like receptor 1
    Toll-like receptor 1 (redirect from TLR1)
    TLR1 recognizes bacterial lipoproteins and glycolipids in complex with TLR2. TLR1 is a cell surface receptor. TLR1 is in humans encoded by the TLR1 gene...
    12 KB (1,377 words) - 21:42, 4 April 2024
  • Thumbnail for Toll-like receptor
    recognized by TLRs, which activate immune cell responses. The TLRs include TLR1, TLR2, TLR3, TLR4, TLR5, TLR6, TLR7, TLR8, TLR9, TLR10, TLR11, TLR12, and...
    61 KB (6,763 words) - 10:28, 1 August 2024
  • bacteria and is recognized by TLR2, which is usually in a heterodimer of with TLR1 or TLR6. Lipoteichoic acid (LTA) from gram-positive bacteria, bacterial lipoproteins...
    13 KB (1,476 words) - 12:50, 13 January 2024
  • Thumbnail for Leprosy
    OMIM Gene LPRS1 10p13 609888 LPRS2 6q25 607572 PARK2, PACRG LPRS3 4q32 246300 TLR2 LPRS4 6p21.3 610988 LTA LPRS5 4p14 613223 TLR1 LPRS6 13q14.11 613407...
    131 KB (13,049 words) - 01:55, 29 August 2024
  • Thumbnail for Atopy
    atopy. Genes for atopy (C11orf30, STAT6, SLC25A46, HLA-DQB1, IL1RL1/IL18R1, TLR1/TLR6/TLR10, LPP, MYC/PVT1, IL2/ADAD1, HLA-B/MICA) tend to be involved in...
    24 KB (2,561 words) - 17:54, 7 July 2024
  • Thumbnail for CD14
    independently deliver triacylated lipoproteins to Toll-like receptor 1 (TLR1) and TLR2 and enhance formation of the ternary signaling complex". The Journal...
    7 KB (845 words) - 09:05, 27 March 2024
  • Thumbnail for Neanderthal
    introgression, which may have aided migration, such as OAS1, STAT2, TLR6, TLR1, TLR10, and several related to immune response. In addition, Neanderthal...
    333 KB (36,168 words) - 00:27, 2 September 2024
  • Retrieved 1 February 2017. Sharma N, Vacher J, Allison JP (May 2019). "TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral...
    17 KB (1,844 words) - 08:01, 29 April 2024
  • Thumbnail for Black guineafowl
    researchers. The black guineafowl's genome includes a toll-like receptor (TLR1) which plays an important role in the bird's immune system. This gene has...
    7 KB (850 words) - 19:00, 23 May 2024
  • NT-4/NT-5 > NT-3 TrkC NTRK3 " NT-3 p75 NGFR " NGF, BDNF, NT3, NT4/5 Toll-like TLR1 TLR1 " TLR2 TLR2 " Peptidoglycan TLR3 TLR3 " polyIC, polyinosine-polycytosine...
    7 KB (350 words) - 19:02, 13 March 2024
  • Thumbnail for Causes of autism
    introgression, which may have aided migration, such as OAS1, STAT2, TLR6, TLR1, TLR10, and several related to immune response. In addition, Neanderthal...
    145 KB (15,733 words) - 23:52, 11 July 2024
  • Thumbnail for Macrophage
    PMC 4400235. PMID 25858805. Sharma N, Vacher J, Allison JP (May 2019). "TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral...
    92 KB (10,131 words) - 14:36, 2 September 2024
  • Thumbnail for Toll-like receptor 2
    Plasmodium falciparum are mainly mediated through the recognition of TLR2/TLR1". Experimental Parasitology. 128 (3): 205–211. doi:10.1016/j.exppara.2011...
    22 KB (2,409 words) - 10:20, 12 August 2024
  • Thumbnail for Interbreeding between archaic and modern humans
    Neanderthal alleles affect expression of the immune genes OAS1/2/3 and TLR1/6/10, which can be specific to cell type and is influenced by environmental...
    91 KB (11,130 words) - 11:57, 20 July 2024
  • Thumbnail for MYD88
    from insects to mammals. TLRs are located either on the cellular surface (TLR1, TLR2, TLR4, TLR5, TLR6) or within endosomes (TLR3, TLR7, TLR8, TLR9) sensing...
    20 KB (2,250 words) - 15:55, 30 July 2024
  • 2 (MRC2) CD281 TLR1; a member of the Toll-like receptor family (TLR) of pattern recognition receptors of the innate immune system. TLR1 recognizes pathogen-associated...
    96 KB (467 words) - 19:33, 6 August 2024
  • Thumbnail for Virulence-related outer membrane protein family
    immune system (VlsE). OspC trigger innate immune system via signaling through TLR1, TLR2 and TLR6 receptors. Members of this group include: PagC, required by...
    11 KB (1,275 words) - 21:34, 13 July 2024
  • tend to dimerize, TLR4 forms homodimers, and TLR6 can dimerize with either TLR1 or TLR2. Interaction of TLRs with their specific PAMP is mediated through...
    43 KB (5,173 words) - 21:02, 10 August 2024
  • Thumbnail for Purpurogallin
    methylation by catechol-O-methyltransferase. It potently and specifically inhibits TLR1/TLR2 activation pathway. Purpurogallin, obtained by oxidation of pyrogallol...
    5 KB (350 words) - 00:14, 29 August 2024
  • Pattern recognition receptor Membrane-bound PRRs Toll-like receptors (TLRs) TLR1 TLR2 TLR3 TLR4 TLR5 TLR6 TLR7 TLR8 TLR9 TLR10 TLR11 TLR12 TLR13 C-type lectin...
    38 KB (2,656 words) - 12:11, 30 October 2023
  • family Lavidaviridae), giant viruses (Megavirales), Ginger 1 transposons, Tlr1 transposons, transpovirons, eukaryotic viruses of the Adenoviridae family...
    10 KB (1,079 words) - 16:02, 12 July 2024
  • signature of common evolutionary history of Polintons, polinton-like viruses, Tlr1 transposons and transpovirons". Virus Evolution. 2 (1): vew019. doi:10.1093/ve/vew019...
    3 KB (295 words) - 01:58, 1 December 2023
  • Thumbnail for Bruce Beutler
    which bear no structural similarity to bacterial lipopeptides, activate the TLR1-TLR2 heterodimer complex that normally acts as a receptor for tri-acylated...
    112 KB (12,093 words) - 21:06, 28 July 2024
  • Thumbnail for Toll-interleukin receptor
    IL18RAP; IL1R1; IL1RAP; IL1RAPL1; IL1RAPL2; IL1RL1; IL1RL2; MYD88; SIGIRR; TLR1; TLR10; TLR2; TLR3; TLR4; TLR5; TLR6; TLR7; TLR8; TLR9; SARM1; Horsefield...
    8 KB (839 words) - 21:44, 4 April 2024
  • "Mycobacterial lipoarabinomannan mediates physical interactions between TLR1 and TLR2 to induce signaling". Journal of Endotoxin Research. 9 (4): 264–8...
    23 KB (2,663 words) - 16:29, 11 December 2023
  • Thumbnail for Murine respirovirus
    (PRR) Toll Like Receptors TLR SeV infection stimulates mRNA expression of TLR1, TLR2, TLR3, and TLR7 in macrophages. This effect is IFN-alpha/beta dependent...
    296 KB (31,942 words) - 21:22, 28 August 2024
  • Thumbnail for FAM114A1
    has 4138 bp. The gene has the following neighbors on the same chromosome: TLR1: Toll-like receptor (TLR) 1 plays a role in pathogen recognition and activation...
    11 KB (721 words) - 13:55, 28 November 2023
  • Q9Y490 16749 TLN2 HGNC:15447 Q9Y4G6 16750 TLNRD1 HGNC:13519 Q9H1K6 16751 TLR1 HGNC:11847 Q15399 16752 TLR2 HGNC:11848 O60603 16753 TLR3 HGNC:11849 O15455...
    242 KB (17 words) - 23:17, 27 April 2024
  • exposure of efti. The investigators contrasted the potency of efti with TLR1-9 agonists which, while inducing IL-10, are unable to induce a Tc1 IFN-γ...
    20 KB (2,722 words) - 21:14, 27 June 2024
  • system), can detect mycobacterial triacylated lipoproteins via TLR2 and TLR1. Tsukamura, M; Mizuno, S (October 1971). "Mycobacterium obuense, a rapidly...
    3 KB (267 words) - 02:44, 1 March 2023