Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres...

Telomerase reverse transcriptase (abbreviated to TERT, or hTERT in humans) is a catalytic subunit of the enzyme telomerase, which, together with the telomerase...

developmental biology in October 2020. Greider discovered the enzyme telomerase in 1984, while she was a graduate student of Elizabeth Blackburn at the...

Telomerase RNA component, also known as TR, TER or TERC, is an ncRNA found in eukaryotes that is a component of telomerase, the enzyme used to extend telomeres...

discovery of how chromosomes are protected by telomeres and the enzyme telomerase. During DNA replication, DNA polymerase cannot replicate the sequences...

Salk Institute for Biological Studies. In 1984, Blackburn co-discovered telomerase, the enzyme that replenishes the telomere, with Carol W. Greider. For...

to activate telomerase more than any other known compound yet discovered: 8.8-fold. This exceeds the activation by other known telomerase activators:...

to telomerase, an enzyme that repairs long repetitive sections of DNA sequences at the ends of chromosomes, referred to as telomeres. Telomerase is expressed...

Greider, and Jack Szostak in the 1980s led to the successful discovery of telomerase (the enzyme responsible for maintaining telomere length) and a better...

reversing it. Cultures not containing telomerase-active pluripotent stem cells would have been populated with telomerase-inactive cells, which would have been...

Retroelements not elsewhere classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme...

syndromes with transfusion-dependent anemia. Imetelstat is an oligonucleotide telomerase inhibitor. The most common adverse reactions include decreased platelets...

various legume species in the genus Astragalus that is purported to have telomerase activation activity. A preliminary in vitro study on human CD4 and CD8...

cancers reactivation of telomerase is actually a required step for malignancy to evolve (see telomere). In a disease where telomerase is affected, it does...

developing and commercializing therapeutic products for cancer that inhibit telomerase. Geron, based in Foster City, California, was founded by gerontologist...

area of research, it is generally believed to play a role in regulating telomerase activity as well as maintaining the heterochromatic state at the ends...

Retroelements not elsewhere classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme...

cells. Like many other cancer cells, HeLa cells have an active version of telomerase during cell division, which copies telomeres over and over again. This...

Epitalon is a synthetic peptide, telomerase activator, and putative anti-aging compound, which was identified as the putative active component of a bovine...

reactions. He also studied telomeres, and his lab discovered an enzyme, TERT (telomerase reverse transcriptase), which is part of the process of restoring telomeres...

percent of cancer cells contain large amounts of an enzyme called telomerase. Telomerase is an enzyme that replenishes the worn away telomeres by adding...

to telomerase, an enzyme that repairs long repetitive sections of DNA sequences at the ends of chromosomes, referred to as telomeres. Telomerase is expressed...

Retroelements not elsewhere classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme...

5'-TTAGGG-3' recruits telomerase. Telomerase acts like other DNA polymerases by extending the 3' end, but, unlike other DNA polymerases, telomerase does not require...

Retroelements not elsewhere classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme...

Retroelements not elsewhere classified Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme...

Metastases suppressor NME2 associates with telomere ends and telomerase and reduces telomerase activity within cells. Oxford University Press. OCLC 794927394...

features that make them "immortal" according to some researchers. The enzyme telomerase is used to extend the cancer cell's life span. While the telomeres of...

PIN2/TERF1-interacting telomerase inhibitor 1, also known as PINX1, is a human gene. PINX1 is also known as PIN2 interacting protein 1. PINX1 is a telomerase inhibitor...

that was the first to successfully identify the genes for human enzyme telomerase. This enzyme is responsible for preventing telomeres from shortening in...