Temozolomide, sold under the brand name Temodar among others, is an anticancer medication used to treat brain tumors such as glioblastoma and anaplastic...
33 KB (2,959 words) - 02:09, 16 July 2024
after which chemotherapy and radiation therapy are used. The medication temozolomide is frequently used as part of chemotherapy. High-dose steroids may be...
78 KB (8,732 words) - 21:33, 5 September 2024
Temozolomide is effective for treating Glioblastoma Multiforme (GBM) compared to radiotherapy alone. A 2013 meta-analysis showed that Temozolomide prolongs...
64 KB (6,986 words) - 19:06, 12 September 2024
received temozolomide for at least 12 months on the 5/28 day cycle, dividing such patients into two groups: "short term" patients receiving temozolomide for...
26 KB (2,938 words) - 02:35, 3 June 2024
treatment had a higher selective cytotoxicity index (0.64-3.36) than temozolomide (0.11-1.13) and reduced both proliferation and cell motility. Euphol...
16 KB (1,715 words) - 03:01, 8 April 2024
MMH is also assumed to be the active methylating agent in the drug Temozolomide. "Monomethylhydrazine - Compound Summary". PubChem Compound. USA: National...
7 KB (483 words) - 09:13, 2 September 2024
chemotherapy or supplementing other treatments for this kind of tumor. Although temozolomide is effective for treating recurrent anaplastic astrocytoma, its role...
8 KB (822 words) - 18:34, 31 July 2024
Nimustine Nitrosoureas Pipobroman Ranimustine Semustine Streptozotocin Temozolomide Thiotepa Treosulfan Triaziquone Triethylenemelamine Trofosfamide Uramustine...
5 KB (324 words) - 12:07, 20 July 2024
in combination with radiotherapy and temozolomide. An in-vitro study showed that a combination of temozolomide and lonidamine at clinically achievable...
4 KB (275 words) - 06:52, 17 March 2024
in size or had completely disappeared". Olaparib in combination with temozolomide demonstrated substantial clinical activity in relapsed small cell lung...
24 KB (2,132 words) - 11:10, 7 September 2024
Too Many Zooz, a band from New York City, U.S. Kodak T-MAX P3200 film Temozolomide, a drug Trimetazidine, a drug TMZ (motorcycle), a Soviet motorcycle manufacturer...
624 bytes (110 words) - 15:24, 22 April 2024
weekly. Cilengitide is well tolerated, in combination with radiation and temozolomide, at a dose of 2000 mg in patients with newly diagnosed glioblastoma,...
10 KB (891 words) - 10:07, 13 January 2024
Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With...
8 KB (619 words) - 19:56, 19 January 2024
mitozolomide, temozolomide) from the nonclassical category. However, other sources list dacarbazine as nonclassical, and some include temozolomide. The platinum...
13 KB (1,449 words) - 12:45, 21 August 2024
H.; et al. (2009). "Phase II Trial of Temozolomide Plus O6-Benzylguanine in Adults with Recurrent, Temozolomide-Resistant Malignant Glioma". Journal of...
5 KB (290 words) - 06:51, 17 March 2024
Several newer agents, including temozolomide and bendamustine, have activity in relapsed SCLC. Of note, temozolomide yielded a response rate of 38% for...
54 KB (5,543 words) - 23:34, 12 September 2024
cancer drug discovered at the Institute of Cancer Research in London. Temozolomide, which has an effect on glioblastoma, discovered by CRUK scientists at...
27 KB (2,457 words) - 18:27, 17 August 2024
people seem to respond to a combination chemo called capecitabine and temozolomide but there is no report that it totally cured people of VIPoma.[citation...
6 KB (658 words) - 12:17, 12 August 2024
virus infection. Ribavirin for the treatment of chronic hepatitis C Temozolomide capsules, an alkylating drug for the treatment of glioblastoma multiforme...
20 KB (1,693 words) - 21:17, 12 September 2024
doxorubicin with streptozocin and fluorouracil (5-FU) and capecitabine with temozolomide.[citation needed] Although marginally effective in well-differentiated...
28 KB (2,476 words) - 13:44, 25 July 2024
to glioblastoma that adds to a traditional cancer cell killing drug, temozolomide, nine older, non-cytotoxic drugs to block growth factors that enhance...
8 KB (1,151 words) - 03:20, 11 August 2024
Trans Sodium Crocetinate (TSC) With Concomitant Radiation Therapy and Temozolomide in Newly Diagnosed Glioblastoma (GBM)". ClinicalTrials.gov. November...
7 KB (541 words) - 19:24, 30 June 2024
and streptozotocin. Tetrazines include dacarbazine, mitozolomide and temozolomide. Aziridines include thiotepa, mytomycin and diaziquone (AZQ). Cisplatin...
155 KB (17,546 words) - 16:49, 16 August 2024
of immune checkpoint inhibitors, dacarbazine and its oral counterpart temozolomide constitute potential treatment options in later lines of therapy. Multiple...
154 KB (16,091 words) - 19:34, 29 August 2024
Following this, patients will undergo chemotherapy, most commonly with Temozolomide. Median time to progression is 10 months. After progression, the median...
7 KB (655 words) - 04:37, 11 June 2024
water extract of S. nigrum could improve the therapeutic efficacy of temozolomide, as well as DTIC, against human MM. Further studies are warranted to...
34 KB (3,789 words) - 16:41, 20 July 2024
Etoglucid Mitobronitol Pipobroman Triazenes (Dacarbazine# Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# Mitomycins Plicamycin)...
31 KB (2,906 words) - 07:45, 19 August 2024
with glioblastoma, a severe type of brain tumor, the cancer medicine temozolomide is more effective in those with a methylation of the gene's promoter...
32 KB (3,857 words) - 22:04, 28 July 2024
invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A)". Oncotarget. 7 (40): 65643–65659...
150 KB (14,340 words) - 09:12, 7 September 2024
Etoglucid Mitobronitol Pipobroman Triazenes (Dacarbazine# Mitozolomide§ Temozolomide) Intercalation Streptomyces (Dactinomycin# Bleomycin# Mitomycins Plicamycin)...
36 KB (3,299 words) - 19:46, 10 August 2024