• Transcobalamins are carrier proteins which bind cobalamin (B12). Transcobalamin I (TC-1), also known as haptocorrin (HC), R-factor, and R-protein is encoded...
    3 KB (330 words) - 06:11, 5 May 2024
  • Thumbnail for Haptocorrin
    Haptocorrin (HC) also known as transcobalamin-1 (TC-1) or cobalophilin is a transcobalamin protein that in humans is encoded by the TCN1 gene. One essential...
    14 KB (1,810 words) - 04:17, 1 April 2024
  • Thumbnail for Intrinsic factor
    intrinsic factor protein is encoded by the CBLIF gene. Haptocorrin (transcobalamin I) is another glycoprotein secreted by the salivary glands which binds...
    13 KB (1,453 words) - 04:02, 10 March 2024
  • Thumbnail for Vitamin B12
    circulating B12, rendering it unavailable for cellular delivery by transcobalamin II. This is conjectured to be a circulating storage function. Several...
    112 KB (12,246 words) - 16:28, 9 July 2024
  • Thumbnail for Methylmalonic acidemias
    deficiency". Orphanet. Retrieved 2024-05-15. "Methylmalonic aciduria due to transcobalamin receptor defect". Orphanet. Retrieved 2024-04-27. "Methylmalonic acidemia...
    49 KB (4,433 words) - 18:08, 16 June 2024
  • Thumbnail for Cyanocobalamin
    three different protein molecules: haptocorrin, intrinsic factor and transcobalamin II. Methylcobalamin Hydroxocobalamin Adenosylcobalamin Cobalamin biosynthesis...
    30 KB (2,638 words) - 05:07, 27 May 2024
  • absorbed into the body. Since the body already has liver receptors for transcobalamin/vitamin B12 saturated by the injection, much of the ingested vitamin...
    10 KB (1,097 words) - 15:01, 17 December 2022
  • to both transcobalamins. Most of the time, 80–94% of vitamin B12 in the blood binds to haptocorrin, while only 6–20% is binds to transcobalamin ll. Only...
    6 KB (705 words) - 18:13, 29 February 2024
  • Thumbnail for Human digestive system
    stomach, bound to a glycoprotein secreted by the salivary glands – transcobalamin I also called haptocorrin, which protects the acid-sensitive vitamin...
    64 KB (8,592 words) - 04:03, 26 June 2024
  • Thumbnail for Folate
    transcobalamines" [Anemias due to disorder of folate, vitamin B12 and transcobalamin metabolism]. La Revue du Praticien (in French). 43 (11): 1358–63. PMID 8235383...
    101 KB (11,048 words) - 22:41, 26 June 2024
  • Thumbnail for Pernicious anemia
    cases of deficiency where myeloproliferative disorders, liver disease, transcobalamin II, or small intestinal bacterial overgrowth are present. Low levels...
    56 KB (6,027 words) - 12:46, 25 April 2024
  • Thumbnail for Vitamin B12 deficiency
    metformin may interfere with B12 dietary absorption. A genetic disorder, transcobalamin II deficiency can be a cause. Nitrous oxide exposure, and recreational...
    118 KB (13,134 words) - 03:56, 27 June 2024
  • A. Hall and P. C. J. Rogers; Hall, C. A.; Rogers, P. C. J. (1991). "Transcobalamin II deficiency: Case report and review of the literature". European Journal...
    70 KB (2,582 words) - 03:15, 16 December 2023
  • Tracheophageal fistula hypospadias Trachoma Tranebjaerg–Svejgaard syndrome Transcobalamin II deficiency Transient erythroblastopenia of childhood Transient global...
    10 KB (849 words) - 03:37, 11 January 2024
  • Thumbnail for Hydroxocobalamin
    adenosylcobalamin. Cobalamins circulate bound to serum proteins called transcobalamins (TC) and haptocorrins. Hydroxocobalamin has a higher affinity to the...
    21 KB (2,017 words) - 18:23, 24 June 2024
  • Thumbnail for MTRR (gene)
    initiated by the endocytosis of cobalamin bound to the plasma protein transcobalamin (II). Cleavage of this complex produces free cobalamin, translocating...
    44 KB (5,274 words) - 18:33, 3 May 2024
  • deficiency Calcium channel defects ORAI1 deficiency STIM1 deficiency Transcobalamin 2 deficiency Immunodeficiency with multiple intestinal atresias (TTC7A...
    19 KB (1,836 words) - 09:52, 5 July 2024
  • Thumbnail for Cubilin
    cobalamin binding kinetics and ligand protection for intrinsic factor, transcobalamin, and haptocorrin". J. Biol. Chem. 277 (12): 9989–96. doi:10.1074/jbc...
    10 KB (1,173 words) - 17:25, 30 March 2024
  • Thumbnail for MNDA
    S2CID 25290353. Ott J, Fràter-Schröder M (1982). "Absence of linkage between transcobalamin II and ABO". Human Genetics. 59 (2): 164–5. doi:10.1007/BF00293068....
    7 KB (793 words) - 23:36, 20 April 2024
  • Thumbnail for Cobalamin biosynthesis
    humans, dietary sources of cobalamin are bound after ingestion as transcobalamins and converted to the coenzyme forms in which they are used. Cobalamin...
    36 KB (3,654 words) - 06:20, 10 June 2024
  • Thumbnail for Neville Colman
    Neville; Goh, Kong-Oo; Herbert, Victor; Klemperer, Martin R. (1983). "Transcobalamin II deficiency associated with unusual bone marrow findings and chromosomal...
    14 KB (1,321 words) - 14:00, 30 May 2024
  • homocystinuria, cblF type; 277380; LMBRD1 Methylmalonic aciduria due to transcobalamin receptor defect; 613646; CD320 Methylmalonic aciduria, cblD type, variant...
    234 KB (18,877 words) - 15:43, 9 May 2024
  • The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)...
    52 KB (4,484 words) - 16:46, 9 February 2024
  • The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)...
    43 KB (3,780 words) - 16:51, 9 February 2024
  • The following is a partial list of the "D" codes for Medical Subject Headings (MeSH), as defined by the United States National Library of Medicine (NLM)...
    133 KB (7,397 words) - 16:43, 9 February 2024