Transferrin receptor protein 1 (TfR1), also known as Cluster of Differentiation 71 (CD71), is a protein that in humans is encoded by the TFRC gene. TfR1...
8 KB (937 words) - 08:12, 4 October 2023
Transferrin receptor (TfR) is a carrier protein for transferrin. It is needed for the import of iron into cells and is regulated in response to intracellular...
9 KB (1,014 words) - 02:23, 28 October 2023
transferrin receptors found in humans denoted as transferrin receptor 1 (TfR1) and transferrin receptor 2 (TfR2). Although both are similar in structure...
24 KB (2,777 words) - 16:03, 10 July 2024
transferrin receptor conventionally refers to the cleaved extracellular portion of transferrin receptor 1 that is released into serum. This receptor is...
3 KB (375 words) - 19:56, 13 August 2023
although its role is minor compared to transferrin receptor 1. This gene is a member of the transferrin receptor-like family and encodes a single-pass...
8 KB (952 words) - 15:36, 4 January 2024
take up iron primarily through receptor-mediated endocytosis via transferrin receptor 1 (TFR1), transferrin receptor 2 (TFR2) and GAPDH. TFR1 has a 30-fold...
46 KB (5,567 words) - 18:09, 20 August 2024
a type of iron overload disorder associated with deficiencies in transferrin receptor 2. It exhibits an autosomal recessive inheritance pattern. The first...
17 KB (1,854 words) - 04:32, 27 September 2023
Lassa mammarenavirus (section Receptors)
Sabia in addition to the non pathogenic Amapari virus, use the transferrin receptor 1. A small aliphatic amino acid at the GP1 glycoprotein amino acid...
21 KB (2,461 words) - 18:07, 27 February 2024
co-develop/commercialize at least one of CytomX Probody's conjugates against CD71 (transferrin receptor 1). In March 2020, AbbVie announced plans to evaluate the Kaletra/Aluvia...
40 KB (3,359 words) - 06:40, 2 August 2024
potential target to attenuate immune rejection. Antibodies CD71/Transferrin receptor-1 CD13 marker for kidney disorder CD33 marker for AML treatment CD4+/CD8+...
14 KB (1,368 words) - 18:49, 18 August 2024
(vesicles up to 1 μm in diameter with connected tubules of approx. 50 nm diameter). Markers include RAB5A and RAB4, Transferrin and its receptor and EEA1. Late...
22 KB (2,647 words) - 07:14, 29 May 2024
bound transferrin, owing to changes in the UV-Vis spectrum. The formation constant for Cr3+ in the C-lobe is 1.41 x 1010 M−1 and 2.04 x 105 M−1 in the...
46 KB (5,094 words) - 19:52, 15 August 2024
Ferroportin (redirect from Ferroportin 1)
hemochromatosis: transferrin receptor-1, ferroportin, ceruloplasmin, ferritin light and heavy chains, iron regulatory proteins (IRP)-1 and -2, and hepcidin"...
21 KB (2,439 words) - 01:30, 28 March 2024
Iron-responsive element-binding protein (category EC 4.2.1)
transferrin receptor mRNA. The transferrin receptor mRNA is rapidly degraded without the IRE-BP attached to it. The cell stops producing transferrin receptors...
8 KB (997 words) - 02:27, 18 October 2022
recycling of human beta 2-adrenergic receptors between the plasma membrane and endosomes containing transferrin receptors". The Journal of Biological Chemistry...
33 KB (3,380 words) - 19:17, 10 July 2024
by the cell (examples include LDL via the LDL receptor or iron via transferrin). The role of receptor-mediated endocytosis is well recognized up take...
10 KB (1,096 words) - 11:02, 3 December 2023
take up iron primarily through receptor-mediated endocytosis via transferrin receptor 1 (TFR1), transferrin receptor 2 (TFR2) and GAPDH. TFR1 has a 30-fold...
44 KB (5,376 words) - 09:18, 1 July 2024
Pearson, Richard D.; Rangel, Gabriel (2018-01-05). "Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax". Science. 359 (6371): 48–55...
12 KB (1,221 words) - 02:23, 27 July 2024
active against all tested mammarenaviruses that use the transferrin receptor 1 as their receptor was under investigation in 2020. Radoshitzky, SR; Buchmeier...
37 KB (4,048 words) - 19:02, 30 July 2024
circulating iron uptake by regulating the interaction of the transferrin receptor with transferrin. The HFE gene contains 7 exons spanning 12 kb. The full-length...
20 KB (2,300 words) - 18:39, 10 March 2024
ferroportin. Ferroportin Q248H also unregulated the expression of transferrin receptor-1 in the same way as wild type. This indicates the ferroportin Q248H...
21 KB (2,165 words) - 00:46, 18 June 2024
Theoretically, a decrease in transferrin could additionally be decreased by an upregulation of transferrin receptors, but the latter does not appear...
11 KB (1,096 words) - 14:00, 24 December 2023
the BBB via transport on brain endothelial receptors such as the insulin receptor or transferrin receptor. The transporter protein acts as a molecular...
20 KB (2,229 words) - 07:06, 1 December 2023
transcripts that encode iron metabolism genes, including ferritin, transferrin receptor 1, ferroportin, HIF2 alpha, and several other transcripts. IRP1 acquires...
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that have different receptors responsible for the receptor-mediated endocytosis of ligands, e.g. low density lipoprotein, transferrin, growth factors, antibodies...
25 KB (2,980 words) - 14:58, 19 June 2024
Interleukin 4 (redirect from Receptors, interleukin-4)
overexpress receptors for various growth factors including epidermal growth factor receptor, FGFR-1 (fibroblast growth factor receptor 1), TfR (transferrin receptor)...
19 KB (2,293 words) - 11:05, 8 March 2024
Punnonen, K; Rajamäki, A; Irjala, K (October 1998). "Serum transferrin receptor and transferrin receptor-ferritin index identify healthy subjects with subclinical...
13 KB (1,432 words) - 08:59, 13 August 2023
Lactoferrin (category Transferrins)
known as lactotransferrin (LTF), is a multifunctional protein of the transferrin family. Lactoferrin is a globular glycoprotein with a molecular mass...
49 KB (5,709 words) - 03:20, 24 June 2024
mutations in genes coding for the iron regulatory proteins hemojuvelin, transferrin receptor-2 and ferroportin. Hereditary hemochromatosis is characterized by...
46 KB (4,693 words) - 09:51, 14 August 2024
Chaturvedi, MM; Aggarwal, BB (2007). "Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear...
11 KB (1,167 words) - 05:27, 13 June 2024