• The translocon (also known as a translocator or translocation channel) is a complex of proteins associated with the translocation of polypeptides across...
    18 KB (2,130 words) - 03:27, 9 December 2024
  • Thumbnail for TIC/TOC complex
    The TIC and TOC complexes are translocons located in the chloroplast of a eukaryotic cell, that is, protein complexes that facilitate the transfer of...
    5 KB (492 words) - 23:50, 26 January 2022
  • Thumbnail for Botany
    "Crystal Structure of Pea Toc34, a Novel GTPase of the Chloroplast Protein Translocon". Nature Structural Biology. 9 (2): 95–100. doi:10.1038/nsb744. PMID 11753431...
    137 KB (14,805 words) - 00:13, 9 January 2025
  • sequence is inserted into the translocon. Ribosomes are then physically docked onto the cytoplasmic face of the translocon and protein synthesis resumes...
    15 KB (1,777 words) - 03:39, 30 December 2024
  • Thumbnail for Transmembrane protein
    normally folded co-translationally within the large transmembrane translocon. The translocon channel provides a highly heterogeneous environment for the nascent...
    21 KB (2,262 words) - 15:51, 18 July 2024
  • Thumbnail for Endoplasmic reticulum
    binding site of the ribosome on the rough endoplasmic reticulum is the translocon. However, the ribosomes are not a stable part of this organelle's structure...
    33 KB (3,711 words) - 10:43, 22 December 2024
  • the polypeptide, it is cleaved off after entering the ER-lumen (via a translocon) by a signal peptidase, and subsequently degraded. As an example, the...
    2 KB (223 words) - 11:13, 17 April 2023
  • ribosome-nascent chain complex) to the protein-conducting channel, also known as the translocon, in the endoplasmic reticulum (ER) membrane. This occurs via the interaction...
    13 KB (1,203 words) - 22:07, 23 April 2024
  • Thumbnail for Chloroplast DNA
    is the most abundant of these. The TIC translocon, or translocon on the inner chloroplast membrane translocon is another protein complex that imports...
    54 KB (5,889 words) - 17:57, 25 October 2024
  • station code TOC protocol, an instant message communications protocol Translocon at the outer membrane of chloroplast, in beta barrel Total organic carbon...
    2 KB (257 words) - 14:56, 24 July 2024
  • Thumbnail for Chloroplast
    complex, or translocon on the outer chloroplast membrane, and the TIC translocon, or translocon on the inner chloroplast membrane translocon. Chloroplast...
    189 KB (19,157 words) - 06:23, 6 December 2024
  • Thumbnail for X chromosome
    paraplegia 16 (complicated, X-linked recessive) SSR4: encoding protein Translocon-associated protein subunit delta TAF7L: encoding protein TATA-box binding...
    42 KB (3,912 words) - 00:18, 23 December 2024
  • The protein is co-translationally inserted in the ER membrane via a translocon and is attached to the ER membrane by its hydrophobic C terminus; the...
    6 KB (656 words) - 16:08, 10 July 2024
  • Thumbnail for Oligosaccharyltransferase
    step in the N-linked glycosylation pathway. OST is a component of the translocon in the endoplasmic reticulum (ER) membrane. A lipid-linked core-oligosaccharide...
    10 KB (1,003 words) - 18:41, 23 January 2024
  • Berkeley, Deshaies discovered Sec61, which comprises the heart of the translocon that mediates insertion of secretory and membrane proteins into the endoplasmic...
    18 KB (2,482 words) - 05:06, 15 February 2024
  • Thumbnail for Cystic fibrosis transmembrane conductance regulator
    bicarbonate transmembrane transporter activity chaperone binding Sec61 translocon complex binding isomerase activity Cellular component cytoplasm recycling...
    61 KB (6,506 words) - 02:55, 24 December 2024
  • University of Utah (PhD) Known for Atomic structures of the ribosome, translocon Scientific career Fields Structural biology Membrane proteins Institutions...
    8 KB (672 words) - 15:46, 24 December 2024
  • Thumbnail for Sec61 alpha 1
    SEC61A1, HSEC61, SEC61, SEC61A, Sec61 alpha 1, Sec61 translocon alpha 1 subunit, HNFJ4, SEC61 translocon subunit alpha 1, ADTKD5 External IDs OMIM: 609213;...
    5 KB (672 words) - 15:36, 23 April 2024
  • Thumbnail for Thylakoid
    targeting peptide (shown in blue). Proteins are imported through the translocon of the outer and inner membrane (Toc and Tic) complexes. After entering...
    37 KB (4,385 words) - 19:18, 26 September 2024
  • Thumbnail for SEC61G
    SEC61G Identifiers Aliases SEC61G, SSS1, Sec61 translocon gamma subunit, SEC61 translocon subunit gamma External IDs OMIM: 609215; MGI: 1202066; HomoloGene:...
    4 KB (529 words) - 09:02, 8 January 2024
  • occurs as soon as the protein sequence passes into the ER through the translocon, where it is glycosylated with a sugar molecule that forms the key ligand...
    31 KB (3,592 words) - 02:08, 11 November 2024
  • translocation channel, positioning the ribosome exit tunnel proximal to the translocon central pore and minimizing exposure of the TMD to cytosol. Insertases...
    8 KB (1,006 words) - 02:00, 4 November 2024
  • Thumbnail for SEC61B
    PMID 17081983. S2CID 7827573. Liao HJ, Carpenter G (2007). "Role of the Sec61 Translocon in EGF Receptor Trafficking to the Nucleus and Gene Expression". Mol....
    7 KB (905 words) - 11:37, 18 August 2023
  • Thumbnail for Adaptive immune system
    in cartilaginous fishes, which have a cluster form as compared to the translocon form in bony fish to mammals. Like TCR and Ig, the MHC is found only in...
    57 KB (7,168 words) - 18:55, 21 November 2024
  • Thumbnail for Chaperone (protein)
    translocation-competent (generally unfolded) state and guides them to the translocon. New functions for chaperones continue to be discovered, such as bacterial...
    29 KB (3,499 words) - 02:11, 21 December 2024
  • membrane in prokaryotes. There, the nascent protein is inserted into the translocon, a membrane-bound protein conducting channel composed of the Sec61 translocation...
    53 KB (6,406 words) - 07:06, 12 November 2024
  • Thumbnail for Secretion
    proteins are translocated across the cytoplasmic membrane by the SecYEG translocon, one of two translocation systems, which requires the presence of an N-terminal...
    26 KB (2,981 words) - 11:14, 25 October 2024
  • protein complex found in all domains of life. As the core component of the translocon, it transports proteins to the endoplasmic reticulum in eukaryotes and...
    7 KB (834 words) - 02:43, 29 November 2023
  • Thumbnail for Martin Spiess
    of translocon function and how proteins are sorted in the cell and transported to their designated organelles. Spiess discovered that the translocon, in...
    4 KB (356 words) - 02:33, 19 October 2023
  • Thumbnail for SSR2
    Translocon-associated protein subunit beta also known as TRAP-beta is a protein that in humans is encoded by the SSR2 gene. The signal sequence receptor...
    4 KB (526 words) - 20:16, 8 April 2022