The translocon (also known as a translocator or translocation channel) is a complex of proteins associated with the translocation of polypeptides across...
18 KB (2,130 words) - 03:27, 9 December 2024
TIC/TOC complex (redirect from TIC translocon)
The TIC and TOC complexes are translocons located in the chloroplast of a eukaryotic cell, that is, protein complexes that facilitate the transfer of...
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"Crystal Structure of Pea Toc34, a Novel GTPase of the Chloroplast Protein Translocon". Nature Structural Biology. 9 (2): 95–100. doi:10.1038/nsb744. PMID 11753431...
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sequence is inserted into the translocon. Ribosomes are then physically docked onto the cytoplasmic face of the translocon and protein synthesis resumes...
15 KB (1,777 words) - 03:39, 30 December 2024
normally folded co-translationally within the large transmembrane translocon. The translocon channel provides a highly heterogeneous environment for the nascent...
21 KB (2,262 words) - 15:51, 18 July 2024
binding site of the ribosome on the rough endoplasmic reticulum is the translocon. However, the ribosomes are not a stable part of this organelle's structure...
33 KB (3,711 words) - 10:43, 22 December 2024
the polypeptide, it is cleaved off after entering the ER-lumen (via a translocon) by a signal peptidase, and subsequently degraded. As an example, the...
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ribosome-nascent chain complex) to the protein-conducting channel, also known as the translocon, in the endoplasmic reticulum (ER) membrane. This occurs via the interaction...
13 KB (1,203 words) - 22:07, 23 April 2024
is the most abundant of these. The TIC translocon, or translocon on the inner chloroplast membrane translocon is another protein complex that imports...
54 KB (5,889 words) - 17:57, 25 October 2024
station code TOC protocol, an instant message communications protocol Translocon at the outer membrane of chloroplast, in beta barrel Total organic carbon...
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complex, or translocon on the outer chloroplast membrane, and the TIC translocon, or translocon on the inner chloroplast membrane translocon. Chloroplast...
189 KB (19,157 words) - 06:23, 6 December 2024
paraplegia 16 (complicated, X-linked recessive) SSR4: encoding protein Translocon-associated protein subunit delta TAF7L: encoding protein TATA-box binding...
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The protein is co-translationally inserted in the ER membrane via a translocon and is attached to the ER membrane by its hydrophobic C terminus; the...
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step in the N-linked glycosylation pathway. OST is a component of the translocon in the endoplasmic reticulum (ER) membrane. A lipid-linked core-oligosaccharide...
10 KB (1,003 words) - 18:41, 23 January 2024
Berkeley, Deshaies discovered Sec61, which comprises the heart of the translocon that mediates insertion of secretory and membrane proteins into the endoplasmic...
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bicarbonate transmembrane transporter activity chaperone binding Sec61 translocon complex binding isomerase activity Cellular component cytoplasm recycling...
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University of Utah (PhD) Known for Atomic structures of the ribosome, translocon Scientific career Fields Structural biology Membrane proteins Institutions...
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SEC61A1, HSEC61, SEC61, SEC61A, Sec61 alpha 1, Sec61 translocon alpha 1 subunit, HNFJ4, SEC61 translocon subunit alpha 1, ADTKD5 External IDs OMIM: 609213;...
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targeting peptide (shown in blue). Proteins are imported through the translocon of the outer and inner membrane (Toc and Tic) complexes. After entering...
37 KB (4,385 words) - 19:18, 26 September 2024
SEC61G Identifiers Aliases SEC61G, SSS1, Sec61 translocon gamma subunit, SEC61 translocon subunit gamma External IDs OMIM: 609215; MGI: 1202066; HomoloGene:...
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occurs as soon as the protein sequence passes into the ER through the translocon, where it is glycosylated with a sugar molecule that forms the key ligand...
31 KB (3,592 words) - 02:08, 11 November 2024
translocation channel, positioning the ribosome exit tunnel proximal to the translocon central pore and minimizing exposure of the TMD to cytosol. Insertases...
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PMID 17081983. S2CID 7827573. Liao HJ, Carpenter G (2007). "Role of the Sec61 Translocon in EGF Receptor Trafficking to the Nucleus and Gene Expression". Mol....
7 KB (905 words) - 11:37, 18 August 2023
in cartilaginous fishes, which have a cluster form as compared to the translocon form in bony fish to mammals. Like TCR and Ig, the MHC is found only in...
57 KB (7,168 words) - 18:55, 21 November 2024
translocation-competent (generally unfolded) state and guides them to the translocon. New functions for chaperones continue to be discovered, such as bacterial...
29 KB (3,499 words) - 02:11, 21 December 2024
membrane in prokaryotes. There, the nascent protein is inserted into the translocon, a membrane-bound protein conducting channel composed of the Sec61 translocation...
53 KB (6,406 words) - 07:06, 12 November 2024
proteins are translocated across the cytoplasmic membrane by the SecYEG translocon, one of two translocation systems, which requires the presence of an N-terminal...
26 KB (2,981 words) - 11:14, 25 October 2024
protein complex found in all domains of life. As the core component of the translocon, it transports proteins to the endoplasmic reticulum in eukaryotes and...
7 KB (834 words) - 02:43, 29 November 2023
of translocon function and how proteins are sorted in the cell and transported to their designated organelles. Spiess discovered that the translocon, in...
4 KB (356 words) - 02:33, 19 October 2023
Translocon-associated protein subunit beta also known as TRAP-beta is a protein that in humans is encoded by the SSR2 gene. The signal sequence receptor...
4 KB (526 words) - 20:16, 8 April 2022