A transposable element (TE), also transposon, or jumping gene, is a type of mobile genetic element, a nucleic acid sequence in DNA that can change its...

transposase is any of a class of enzymes capable of binding to the end of a transposon and catalysing its movement to another part of a genome, typically by...

The Tn3 transposon is a 4957 base pair mobile genetic element, found in prokaryotes. It encodes three proteins: β-lactamase, an enzyme that confers resistance...

Transposon silencing is a form of transcriptional gene silencing targeting transposons. Transcriptional gene silencing is a product of histone modifications...

The Sleeping Beauty transposon system is a synthetic DNA transposon designed to introduce precisely defined DNA sequences into the chromosomes of vertebrate...

Transposon insertion sequencing (Tn-seq) combines transposon insertional mutagenesis with massively parallel sequencing (MPS) of the transposon insertion...

DNA transposons are DNA sequences, sometimes referred to "jumping genes", that can move and integrate to different locations within the genome. They are...

Transposon mutagenesis, or transposition mutagenesis, is a biological process that allows genes to be transferred to a host organism's chromosome, interrupting...

CRISPR-associated transposons or CASTs are mobile genetic elements (MGEs) that have evolved to make use of minimal CRISPR systems for RNA-guided transposition...

hAT transposons are a superfamily of DNA transposons, or Class II transposable elements, that are common in the genomes of plants, animals, and fungi....

A composite transposon is similar in function to simple transposons and insertion sequence (IS) elements in that it has protein coding DNA segments flanked...

Tc1/mariner is a class and superfamily of interspersed repeats DNA (Class II) transposons. The elements of this class are found in all animals, including humans...

The PiggyBac (PB) transposon system employs a genetically engineered transposase enzyme to insert a gene into a cell's genome. It is built upon the natural...

transposon tagging is a process where transposons (transposable elements) are amplified inside a biological cell by a tagging technique. Transposon tagging...

A simple transposon also called "conservative transposon" is an insertion sequence (IS element) that contains its own coding transposase between the short...

target DNA covalently bind during the formation of a Holliday junction. Transposons elements are DNA sequences that can change its position within the genome...

Transposons are semi-parasitic DNA sequences which can replicate and spread through the host's genome. They can be harnessed as a genetic tool for analysis...

called a mobilome, which is composed of a large number of plasmids, transposons and viruses. Plasmids: These are generally circular extrachromosomal...

Transposition is the process by which a specific genetic sequence, known as a transposon, is moved from one location of the genome to another. Simple, or conservative...

inactive transposons from the salmonid subfamily of elements, was “awoken” to form the transposon named Sleeping Beauty. SB, like other DNA transposons, mobilizes...

using transposons. In the first case, annotated individual genes (or ORFs) are completely deleted from the genome in a systematic way. In transposon-mediated...

expression of transposons in nervous system tissues have been observed. In a study conducted on vertebrates, the expression of transposons during development...

flank the transposon and catalyzes its excision and reinsertion in a new site. This cut-and-paste mechanism typically reinserts transposons near their...

Sciences in 1944. During the 1940s and 1950s, McClintock discovered transposons and used it to demonstrate that genes are responsible for turning physical...

to smaller and less developed genomes (genomic reduction) assisted by transposon expansions. Only a handful of luminescent symbiont species can associate...

dsDNA breaks in ovarian germ cells. The role of the piwi-piRNA pathway in transposon silencing may be responsible for the reduction in dsDNA breaks in germ...

some junk DNA in their genomes—mostly, pseudogenes and fragments of transposons and viruses—but it is possible that some organisms have substantial amounts...

implicated in the transposition activity (they are thus different from other transposons, which also carry accessory genes such as antibiotic resistance genes)...

that encode transposases, which are the main component of transposons. Many kinds of transposon are found adjacent to inverted repeats, which could be mistaken...

each side of the transposon. Such an insertion could intronize the transposon without disrupting the coding sequence when a transposon inserts into the...