• Thumbnail for Trifluoromethyl group
    The trifluoromethyl group is a functional group that has the formula -CF3. The naming of is group is derived from the methyl group (which has the formula...
    4 KB (426 words) - 15:59, 7 November 2024
  • organic chemistry describes any organic reaction that introduces a trifluoromethyl group in an organic compound. Trifluoromethylated compounds are of some...
    43 KB (4,064 words) - 06:38, 27 April 2024
  • formed. An electron donating group (EDG) or electron releasing group (ERG, Z in structural formulas) is an atom or functional group that donates some of its...
    27 KB (2,728 words) - 23:10, 24 March 2024
  • Thumbnail for Triflate
    additional stabilization is achieved by the trifluoromethyl group, which acts as a strong electron-withdrawing group using the sulfur atom as a bridge. Triflates...
    5 KB (597 words) - 11:48, 26 August 2024
  • Thumbnail for Diazonium compound
    Diazonium compound (category Functional groups)
    diazonium salts are a group of organic compounds sharing a common functional group [R−N+≡N]X− where R can be any organic group, such as an alkyl or an...
    32 KB (3,277 words) - 09:54, 9 September 2024
  • Thumbnail for Trifluoromethoxy group
    3 whose hydrogen atoms are replaced by fluorine atoms; or as a trifluoromethyl group attached to the rest of the molecule by a bridging oxygen atom;...
    930 bytes (95 words) - 15:52, 8 January 2024
  • Thumbnail for Trifluoroacetic acid
    fluorine atoms and consequent electron-withdrawing nature of the trifluoromethyl group weakens the oxygen-hydrogen bond (allowing for greater acidity)...
    16 KB (1,367 words) - 14:27, 25 November 2024
  • Thumbnail for Fluorine
    replaces some fluorine atoms with trifluoromethyl groups, perfluoroalkoxy alkanes do the same with trifluoromethoxy groups, and Nafion contains perfluoroether...
    157 KB (15,334 words) - 14:36, 6 November 2024
  • Thumbnail for Hydrofluorocarbon
    drugs and agrochemicals contain only one fluorine center or one trifluoromethyl group. Unlike other greenhouse gases in the Paris Agreement, hydrofluorocarbons...
    7 KB (770 words) - 01:58, 22 November 2024
  • Thumbnail for Sulfonate
    Sulfonate (category Functional groups)
    esters are named. For example, if the R2 group is a methyl group and the R1 group is a trifluoromethyl group, the resulting compound is methyl trifluoromethanesulfonate...
    5 KB (552 words) - 13:49, 4 September 2024
  • drugs and agrochemicals contain only one fluorine center or one trifluoromethyl group. Unlike other greenhouse gases in the Paris Agreement, hydrofluorocarbons...
    41 KB (4,534 words) - 14:34, 22 September 2024
  • Halocarbon (redirect from Halo group)
    organohalides. Notably, many pharmaceuticals such as Prozac have trifluoromethyl groups. For information on inorganic halide chemistry, see halide. Halocarbons...
    17 KB (1,893 words) - 07:22, 9 August 2024
  • Thumbnail for Clenbuterol
    (same structure as clenbuterol but one of the chloro groups has been changed to a trifluoromethyl group instead). Cimaterol Center for Veterinary Medicine...
    20 KB (1,891 words) - 13:52, 22 August 2024
  • Thumbnail for Celecoxib
    Celecoxib (category Trifluoromethyl compounds)
    system has low steric hindrance to maximize potency, while the 3-trifluoromethyl group provides superior selectivity and potency. To explain the selectivity...
    61 KB (6,086 words) - 22:34, 7 November 2024
  • Thumbnail for Trifluoromethyltrimethylsilane
    Trifluoromethyltrimethylsilane (category Trifluoromethyl compounds)
    a reagent used in organic chemistry for the introduction of the trifluoromethyl group. The compound was first prepared in 1984 by Ingo Ruppert and further...
    6 KB (506 words) - 14:27, 1 May 2024
  • Thumbnail for Trifluoronitrosomethane
    Trifluoronitrosomethane (category Trifluoromethyl compounds)
    TFNM) is a toxic organic compound consisting of a trifluoromethyl group covalently bound to a nitroso group. Its distinctive deep blue color is unusual for...
    5 KB (349 words) - 11:23, 22 July 2024
  • Thumbnail for 2,2,2-Trifluoroethanol
    2,2,2-Trifluoroethanol (category Trifluoromethyl compounds)
    smell reminiscent of ethanol. Due to the electronegativity of the trifluoromethyl group, this alcohol exhibits a stronger acidic character compared to ethanol...
    8 KB (626 words) - 17:50, 15 January 2024
  • Thumbnail for Trichloromethyl group
    principle, the trichloromethyl group generally lowers the basicity of organic compounds, e.g. trichloroethanol. Trifluoromethyl group Trichloromethoxy "Trichloromethyl...
    2 KB (161 words) - 05:07, 8 January 2024
  • Thumbnail for 2C-TFM
    2C-CF3, a name derived from the Para-trifluoromethyl group it contains. 2C-TFM is a code that represents 4-trifluoromethyl-2,5-dimethoxyphenethylamine. The...
    7 KB (635 words) - 20:10, 24 April 2024
  • interaction between the trifluoromethyl group and the hydrophobic pocket created by Ile-293, Leu-298, Leu-354, and Val-379. This group can also be linked to...
    56 KB (6,470 words) - 20:27, 19 November 2024
  • species bis(trifluoromethyl)acetolactone ((CF 3) 2C 2O 2), which has increased electronic stabilisation due to its two trifluoromethyl groups, is known...
    2 KB (195 words) - 18:07, 1 January 2024
  • timoprazole was the benzimidazole part of its structure. Addition of a trifluoromethyl group to the benzimidazole moiety led to a series of very active compounds...
    41 KB (4,750 words) - 15:40, 17 November 2024
  • Thumbnail for Geminal diol
    constant is about 10+6, due to the electron withdrawing effect of the trifluoromethyl groups. Similarly, the conversion of chloral (Cl 3C)HC=O to chloral hydrate...
    3 KB (331 words) - 10:55, 6 January 2022
  • Thumbnail for Tetrakis(3,5-bis(trifluoromethyl)phenyl)borate
    Tetrakis[3,5-bis(trifluoromethyl)phenyl]borate is an anion with chemical formula [{3,5-(CF3)2C6H3}4B]−, which is commonly abbreviated as [BArF4]−, indicating...
    11 KB (1,061 words) - 05:49, 25 June 2024
  • Thumbnail for Sodium trifluoromethanesulfinate
    Sodium trifluoromethanesulfinate (category Trifluoromethyl compounds)
    this compound was found to be a suitable reagent for introducing trifluoromethyl groups onto electron-rich aromatic compounds by Langlois; this reagent...
    4 KB (290 words) - 14:52, 24 January 2024
  • Thumbnail for Togni reagent II
    Togni reagent II (1-trifluoromethyl-1,2-benziodoxol-3(1H)-one) is a chemical compound used in organic synthesis for direct electrophilic trifluoromethylation...
    8 KB (641 words) - 15:17, 26 February 2024
  • Thumbnail for Functional group
    functional group is a substituent or moiety in a molecule that causes the molecule's characteristic chemical reactions. The same functional group will undergo...
    32 KB (1,230 words) - 12:24, 22 October 2024
  • Thumbnail for Enantiomer self-disproportionation
    collected. A presence of a strong electronegative group in the substrate such as the trifluoromethyl group is a prerequisite. The effect disappears when a...
    3 KB (343 words) - 16:29, 14 September 2024
  • Thumbnail for Alkoxy group
    alkoxy group is an alkyl group which is singularly bonded to oxygen; thus R−O. Denoted usually with apostrophe('). The range of alkoxy groups is vast...
    2 KB (197 words) - 08:43, 18 December 2023
  • Thumbnail for Trifluoromethylphenylpiperazine
    System Aktów Prawnych. Retrieved 17 June 2011. "4-(Piperazin-1-yl)-2-(trifluoromethyl)phenol". "Erowid TFMPP Vault: Basics". Erowid. Retrieved 2014-02-15...
    14 KB (1,276 words) - 22:46, 23 November 2024