U-50488 is a drug which acts as a highly selective κ-opioid agonist, but without any μ-opioid antagonist effects. It has analgesic, diuretic and antitussive...
5 KB (322 words) - 17:49, 8 February 2024
discovered that U-47700 was the most active. U-47700 became the lead compound of selective kappa-opioid receptor ligands such as U-50488, U-51754 (containing...
24 KB (2,373 words) - 04:19, 17 July 2024
morphine. It is illegal in Virginia. AH-7921 U-48800 U-49900 U-50488 U-69,593 U-77891 "3,4-metylendioxi-U-47700" (PDF). Åklagarmyndigheten. Sweden. 2019. Popławska...
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Spiradoline (U-62,066) TH-030418 Thienorphine Tifluadom Tricyclic antidepressants (e.g., amitriptyline, desipramine, imipramine, nortriptyline) U-50488 U-54,494A...
5 KB (468 words) - 15:12, 10 March 2024
κ-opioid receptor agonist such as U-50488 into an μ-opioid receptor agonist, as well as producing a semi-rigid derivative of U-47700. This would help elucidate...
4 KB (303 words) - 17:35, 8 June 2024
linked to numerous drug overdose cases. 3,4-MDO-U-47700 AH-7921 Butorphanol Pentazocine U-50488 U-69,593 U-77891 Gampfer TM, Richter LH, Schäper J, Wagmann...
4 KB (326 words) - 05:18, 6 May 2024
2023. Retrieved 2 November 2023. Stromgaard K, Krogsgaard-Larsen P, Madsen U (2009). Textbook of Drug Design and Discovery, Fourth Edition. CRC Press....
222 KB (19,665 words) - 02:48, 7 July 2024
Spiradoline (U-62,066) TH-030418 Thienorphine Tifluadom Tricyclic antidepressants (e.g., amitriptyline, desipramine, imipramine, nortriptyline) U-50488 U-54,494A...
11 KB (1,206 words) - 08:53, 6 June 2024
4254–76. doi:10.1111/bph.13222. PMC 4556466. PMID 26075331. Kraus C, Rabl U, Vanicek T, Carlberg L, Popovic A, Spies M, et al. (March 2017). "Administration...
118 KB (11,373 words) - 01:29, 11 July 2024
Proxorphan Racemethorphan Racemorphan Salvinorin A Spiradoline Tifluadom U-50488 U-69,593 Xorphanol Oneirogens Calea zacatechichi Silene capensis Galantamine...
2 KB (149 words) - 10:14, 2 July 2024
doi:10.3389/fmed.2016.00044. PMC 5064048. PMID 27790616. Dinnendahl V, Fricke U, eds. (1982). Arzneistoff-Profile (in German). Eschborn, Germany: Govi Pharmazeutischer...
12 KB (902 words) - 09:03, 15 August 2023
tar heroin distribution has steadily risen in recent years, while that of U.S. East Coast powder varieties has dropped; heroin production in Colombia...
13 KB (1,683 words) - 21:40, 1 July 2024
Spiradoline (U-62,066) TH-030418 Thienorphine Tifluadom Tricyclic antidepressants (e.g., amitriptyline, desipramine, imipramine, nortriptyline) U-50488 U-54,494A...
34 KB (3,196 words) - 20:55, 27 June 2024
Spiradoline (U-62,066) TH-030418 Thienorphine Tifluadom Tricyclic antidepressants (e.g., amitriptyline, desipramine, imipramine, nortriptyline) U-50488 U-54,494A...
10 KB (768 words) - 21:54, 2 February 2024
is neuroprotective against hypoxia/ischemia. The selective KOR agonist U-50488 protected rats against supramaximal electroshock seizures, indicating that...
67 KB (7,675 words) - 03:40, 2 May 2024
Spiradoline (U-62,066) TH-030418 Thienorphine Tifluadom Tricyclic antidepressants (e.g., amitriptyline, desipramine, imipramine, nortriptyline) U-50488 U-54,494A...
11 KB (775 words) - 00:03, 15 July 2024
Paregoric (section Paregoric, U.S.P. formula)
paregoric is powdered opium. In the United States the formula for Paregoric U.S.P. is a tincture of opium 40 ml, anise oil 4 ml, benzoic acid 4 g, camphor...
23 KB (3,042 words) - 21:32, 27 May 2024
their contributions to an alleged 400 acetaminophen-related deaths in the U.S. each year, that were attributed to acetaminophen overdose and associated...
7 KB (395 words) - 20:34, 7 June 2024
Proxorphan Racemethorphan Racemorphan Salvinorin A Spiradoline Tifluadom U-50488 U-69,593 Xorphanol Oneirogens Calea zacatechichi Silene capensis Galantamine...
36 KB (4,142 words) - 18:59, 15 July 2024
Proxorphan Racemethorphan Racemorphan Salvinorin A Spiradoline Tifluadom U-50488 U-69,593 Xorphanol Oneirogens Calea zacatechichi Silene capensis Galantamine...
12 KB (1,004 words) - 00:06, 30 April 2024
Narcotic (section U.S. v. Stieren)
typically has negative connotations. When used in a legal context in the U.S., a narcotic drug is totally prohibited, such as heroin, or one that is...
19 KB (2,361 words) - 14:07, 2 July 2024
Spiradoline (U-62,066) TH-030418 Thienorphine Tifluadom Tricyclic antidepressants (e.g., amitriptyline, desipramine, imipramine, nortriptyline) U-50488 U-54,494A...
14 KB (1,276 words) - 08:55, 16 July 2024
doi:10.1155/2017/1546125. PMC 5525068. PMID 28781901. Enkephalins at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Nosek, Thomas...
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been detected in multiple fatalities in Europe since March 2019 and in the U.S. since August 2019, as reported by NPS Discovery, the Center for Forensic...
12 KB (1,030 words) - 00:50, 14 April 2024
downregulation) of the human KOR relative to the prototypical KOR agonist U-50488.[citation needed] Salvinorin A is capable of inhibiting excess intestinal...
39 KB (3,838 words) - 06:43, 19 May 2024
2023. Retrieved 26 January 2023. Lamy FR, Daniulaityte R, Barratt MJ, Lokala U, Sheth A, Carlson RG (June 2020). "Listed for sale: Analyzing data on fentanyl...
173 KB (15,974 words) - 04:35, 16 July 2024
Spiradoline (U-62,066) TH-030418 Thienorphine Tifluadom Tricyclic antidepressants (e.g., amitriptyline, desipramine, imipramine, nortriptyline) U-50488 U-54,494A...
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opioid in the pharmaceutical industry. In-drug evidence was submitted to U.S. federal state and local forensic laboratories as reported by the Drug Enforcement...
22 KB (1,892 words) - 01:28, 13 June 2024
Proxorphan Racemethorphan Racemorphan Salvinorin A Spiradoline Tifluadom U-50488 U-69,593 Xorphanol Oneirogens Calea zacatechichi Silene capensis Galantamine...
4 KB (289 words) - 04:22, 18 June 2024
under state law, psylocibin mushrooms remain illegal under (seldom enforced) U.S. federal law.) Other jurisdictions in the United States where psilocybin...
45 KB (4,457 words) - 16:45, 3 July 2024