U.S. Route 1 (US 1) is the easternmost and longest of the major north–south routes of the older 1920s era United States Numbered Highway System, running...

U.S. Route 113 (US 113) is a U.S. Highway that is a spur of US 13 in the U.S. states of Maryland and Delaware. The route runs 74.75 miles (120.30 km) from...

U.S. Route 140 (Pennsylvania "Legislative Route 42") was a U.S. highway connecting Gettysburg, Pennsylvania, to Baltimore, Maryland. The route was deleted...

U.S. Route 240 is a defunct designation for a short, but once very important, segment of highway between Frederick, Maryland, and Washington, D.C. It is...

U.S. Route 222 (US 222) is a U.S. Highway that is a spur of US 22 in the states of Maryland and Pennsylvania. It runs for 95 miles (153 km) from US 1...

U.S. Route 111 (US 111) was a U.S. Highway that extended from Baltimore, Maryland north to the Harrisburg, Pennsylvania area. It replaced part of the...

U.S. Route 1 or U.S. Highway 1 (US 1) is a major north–south United States Numbered Highway that serves the East Coast of the United States. It runs 2...

routes of U.S. Route 1 (US 1) exist, from Florida to Maine. In order from south to north, separated by type, these special routes are as follows. U.S...

Pensacola, Florida, to the western suburbs of Baltimore, Maryland. In the U.S. state of Maryland, US 29 is a major highway that emerges from Washington DC...

City, Maryland, on the Atlantic Ocean. In the U.S. state of Maryland, US 50 exists in two sections. The longer of these serves as a major route connecting...

U.S. Route 50 or U.S. Highway 50 (US 50) is a major east–west route of the U.S. Highway system, stretching 3,019 miles (4,859 km) from Interstate 80 (I-80)...

Corner, Delaware, at Delaware Route 1 to Sarasota, Florida, at U.S. Route 41. It passes through the states of Delaware, Maryland, Virginia, North Carolina...

U.S. Route 522 (US 522) is a spur route of US 22 in the states of Virginia, West Virginia, Maryland, and Pennsylvania. The U.S. Highway travels in a north-south...

U.S. Route 40 (US 40) in the U.S. state of Maryland runs from Garrett County in Western Maryland to Cecil County in the state's northeastern corner. With...

U.S. Route 1 Alternate (US 1 Alt.) is an alternate route of US 1 in the U.S. state of Maryland. The highway runs 3.92 miles (6.31 km) between intersections...

U.S. Route 301 (US 301) in the state of Maryland is a major highway that runs 122.85 miles (197.71 km) from the Governor Harry W. Nice Memorial Bridge...

U.S. Route 340 (US 340) is a spur route of US 40, and runs from Greenville, Virginia, to Frederick, Maryland. In Virginia, it runs north–south, parallel...

in the 1950s. US 15 was relocated to part of the freeway; the old route of the U.S. Highway through downtown Frederick became part of Maryland Route 355...

U.S. Route 11 (US 11) is a part of the United States Numbered Highway System that runs from New Orleans, Louisiana, to Rouses Point, New York. In Maryland...

U.S. Route 1 (US 1) is a major north–south U.S. Route, extending from Key West, Florida, in the south to Fort Kent, Maine, at the Canada–United States...

until the freeway's construction was completed in 1991, it was designated as U.S. Route 48 (US 48). In Maryland, the highway is known as the National Freeway...

U.S. Route 219 (US 219) is a part of the U.S. Highway System that runs from Rich Creek, Virginia, to West Seneca, New York. In the U.S. state of Maryland...

U.S. Route 1 Business (US 1 Bus.) is a business route of US 1 in the U.S. state of Maryland. The highway runs 6.90 miles (11.10 km) from US 1 and Maryland...

U.S. Route 40 or U.S. Highway 40 (US 40), also known as the Main Street of America (a nickname shared with U.S. Route 66), is a major east–west United...

southern terminus at US 90 and US 98 in Pensacola to its northern terminus at Maryland Route 99 (MD 99) in Ellicott City. The section of US 29 between Greensboro...

U.S. Route 13 or U.S. Highway 13 (US 13) is a north–south United States Numbered Highway established in 1926 that runs for 518 miles (834 km) from Interstate...

Maryland Route 213 (MD 213) is a 68.25-mile (109.84 km) state highway located on the Eastern Shore of Maryland in the United States. The route runs from...

Carolina, Virginia, Maryland, Pennsylvania, and New York. The route is signed north–south, from US 17 Alternate (US 17 Alt.) in Walterboro, South Carolina...

from U.S. Route 1 (US 1)/US 40 Truck in Baltimore north to the Pennsylvania state line in Maryland Line, where the highway continues as State Route 3001...

Bypass. The route shares a concurrency with US 50 along a portion of the Salisbury Bypass. US 13 was designated through Maryland when the U.S. Numbered...