Vimentin is a structural protein that in humans is encoded by the VIM gene. Its name comes from the Latin vimentum which refers to an array of flexible...
23 KB (2,529 words) - 19:42, 3 April 2024
Detection of autoantibodies against mutated citrullinated vimentin is part of rheumatoid arthritis (RA) diagnostics, especially in sera negative for rheumatoid...
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be enzymatically converted into citrulline residues in proteins such as vimentin, by a process called citrullination. If their shapes are significantly...
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primitive mesenchyme. Hence, they express the intermediate filament protein vimentin, a feature used as a marker to distinguish their mesodermal origin. However...
14 KB (1,677 words) - 11:44, 29 April 2024
sequences across IF families. The N-terminal "head domain" binds DNA. Vimentin heads are able to alter nuclear architecture and chromatin distribution...
30 KB (3,168 words) - 14:29, 25 April 2024
The vimentin 3′ UTR protein-binding region is an RNA element that contains a Y-shaped structure which has been shown to have protein-binding activity....
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activating Vimentin during EMT. PKC-iota inhibition or knockdown resulted in an increase in E-cadherin and RhoA levels while decreasing total Vimentin, phosphorylated...
42 KB (4,999 words) - 10:20, 16 February 2024
they were thought to be cytoskeletal elements and to consist primarily of vimentin. However, more recent research suggested that that was incorrect and that...
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Abundant mucin with clefts. Up to 30% have an associated epithelial component Vimentin; variable staining with CD34, factor XIIIA, SMA1, MSA2 and S-100 20–30%...
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related to the other three non-epithelial type III IF family members, vimentin, desmin and peripherin, which are all involved in the structure and function...
28 KB (3,300 words) - 15:40, 7 June 2024
integron-encoded metallo-β-lactamase, a type of Beta-lactamase enzyme Vimentin, a protein VIM-1, a single board computer Vendor Independent Messaging...
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citrullinated vimentin (MCV) may be useful for monitoring effects of RA therapy. An ELISA system utilises genetically modified citrullinated vimentin (MCV),...
17 KB (1,960 words) - 04:49, 12 December 2023
Masazumi (September 2001). "Subcellular Distribution of Cytokeratin and Vimentin in Malignant Rhabdoid Tumor: Three-Dimensional Imaging with Confocal Laser...
39 KB (3,016 words) - 15:08, 13 July 2024
it binds to cell surface nucleolin, and induces the expression of vimentin. Vimentin is important in the epithelial–mesenchymal transition associated with...
148 KB (16,590 words) - 21:56, 6 July 2024
and several histone proteins, whereas other proteins, such as fibrin and vimentin are susceptible to citrullination during cell death and tissue inflammation...
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mainly found in epithelial cells. Type 3 intermediate filaments contain vimentin. They can be found in a variety of cells which include smooth muscle cells...
14 KB (1,806 words) - 21:19, 11 November 2023
examination. Immunohistochemistry stains positive against the proteins vimentin and S-100, and points to an ectodermal origin for the nodules. Their precise...
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Immunofluorescence image of HeLa cells grown in tissue culture and stained with antibody to actin in green, vimentin in red and DNA in blue...
48 KB (5,642 words) - 15:16, 17 July 2024
CEA and p16 positive and estrogen receptor, progesterone receptor and vimentin negative. Cervical pregnancy This article incorporates text in the public...
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Type 1/2 (Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear...
18 KB (2,154 words) - 07:37, 20 April 2024
antibody targeted against glioma. It works by binding to the ecto-domain of vimentin on the surface of cancer cells. developed by Nascent Biotech. It is in...
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reorganization consists of vimentin being phosphorylated at Ser56 by a p21 activated kinase, resulting in some disassembly of vimentin polymers. Also, the number...
37 KB (4,738 words) - 20:27, 18 July 2024
whereas mesenchymal cells express those of N-cadherin, fibronectin and vimentin. Thus, EMT entails profound morphological and phenotypic changes to a cell...
59 KB (6,833 words) - 23:23, 18 May 2024
tissues. Some of the subunit proteins of intermediate filaments include vimentin, desmin, lamin (lamins A, B and C), keratin (multiple acidic and basic...
60 KB (6,271 words) - 16:07, 17 July 2024
clusters, nests, and cords. Immunohistochemistry is typically positive for vimentin, cytokeratin, CD10, p53, and WT-1. Small cell ovarian carcinoma of the...
196 KB (20,969 words) - 05:49, 19 July 2024
research also suggests a genetic predisposition due to an expression of vimentin, which indicates cellular migration by the keratoblasts embryological development...
20 KB (2,037 words) - 17:57, 2 July 2024
correlated with the endoplasmic reticulum. Recent evidence suggests that vimentin, one of the components of the cytoskeleton, is also critical to the association...
166 KB (18,360 words) - 05:40, 16 July 2024
65-year-old male.[citation needed] The cells exhibit CK5.6, AE1/AE3, E-cadherin, vimentin, chromogranin A, synaptophysin, SSTR2, and NTR1, but not CD56. The cells...
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keratins which are expressed in epithelia. Type III contains the proteins vimentin, desmin, peripherin and glial fibrillary acidic protein (GFAP). Type IV...
25 KB (2,579 words) - 11:02, 31 August 2023
muscular dystrophy. Different intermediate filaments are: made of vimentins. Vimentin intermediate filaments are in general present in mesenchymal cells...
45 KB (5,121 words) - 06:34, 27 May 2024