Vpu is an accessory protein that in HIV is encoded by the vpu gene. Vpu stands for "Viral Protein U". The Vpu protein acts in the degradation of CD4 in...
11 KB (1,419 words) - 04:26, 15 April 2024
target for ERAD. However, HIV produces the membrane protein Vpu that binds to CD4. The Vpu protein mainly retains the CD4 in the ER by SCFβ-TrCP-dependent...
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vision tasks Viral protein U (Vpu), a regulatory protein found in HIV-1 Vancouver Police Union, a trade union in Canada Search for "vpu" on Wikipedia. All...
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(November 2001). "The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent...
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Structure and genome of HIV (redirect from Hiv envelope protein gp160)
vpu (Virus protein U) - Vpu is specific to HIV-1. It is a class I oligomeric integral membrane phosphoprotein with numerous biological functions. Vpu...
33 KB (3,936 words) - 19:54, 3 July 2024
class I and class II molecules. Nef also interacts with SH3 domains. The vpu protein (p16) influences the release of new virus particles from infected cells...
125 KB (14,365 words) - 18:21, 14 August 2024
CSNK2B (category Protein domains)
(1996). "The human immunodeficiency virus type 1 Vpu protein: a potential regulator of proteolysis and protein transport in the mammalian secretory pathway"...
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Ubiquitin (category Protein structure)
JS (April 2010). "Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps". PLOS Pathogens...
98 KB (11,068 words) - 18:53, 17 August 2024
non-structural proteins, named Viral Protein U (Vpu) and Viral Protein R (Vpr), part of a new class of retroviral proteins – designated accessory proteins – that...
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SIVs use the Nef protein to remove tetherin from the cell membrane whereas HIV-1 uses the Vpu protein degrade the defence protein. Tetherin is a conserved...
31 KB (3,863 words) - 12:36, 25 January 2024
Accessory proteins: Nef: negative factor Vpr: regulatory protein Vif: APOBEC3 inhibitor Vpu/Vpx: unique to each type of HIV p6: part of gag Serological...
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CD4 (category Protein domains)
Pacyniak E, Gomez LM, Gomez ML, Stephens EB (July 2004). "Vpu: a multifunctional protein that enhances the pathogenesis of human immunodeficiency virus...
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HIV-1 overcomes this restriction through vpu. Vpu interacts with tetherin by interacting with the protein at its transmembrane domain and recruiting...
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VP40 (redirect from Vp40 protein domain)
In molecular biology, VP40 is the name of a viral matrix protein. Most commonly, it is found in the Ebola virus (EBOV), a type of non-segmented, negative-strand...
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Viroporin (category Viral protein class)
established functional effects exerted through protein-protein interactions. For example, the HIV-1 viroporin Vpu promotes viral budding through interactions...
20 KB (1,967 words) - 00:33, 29 November 2023
capsid protein is the most abundant HIV protein with each virus containing approximately 1,500 to 3,000 p24 molecules. It is the major structural protein within...
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(December 2001). "Association of Vpu-binding protein with microtubules and Vpu-dependent redistribution of HIV-1 Gag protein". Virology. 291 (2): 198–207...
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Vpx (redirect from Vpx (Viral Protein))
structure to the protein Vpr that is carried by SIV and HIV-2 as well as HIV-1. Vpx is one of five accessory proteins (Vif, Vpx, Vpr, Vpu, and Nef) carried...
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S, et al. (2001). "The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent...
11 KB (1,410 words) - 15:45, 23 December 2023
HIV-1 accessory protein Vpu. Subsequently, another inhibitor of HIV-1 replication was discovered in his lab, Mx2, a cellular protein shown to inhibit...
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BTRC (gene) (redirect from Beta-transducin repeat-containing proteins)
identified as a cellular ubiquitin ligase that is bound by the HIV-1 Vpu viral protein to eliminate cellular CD4 by connecting it to the proteolytic machinery...
28 KB (3,356 words) - 01:22, 22 March 2024
Rev (HIV) (category Viral regulatory and accessory proteins)
unspliced gag and pol transcripts and incompletely spliced env, vif, vpr and vpu transcripts at the RRE, facilitating export to the cytoplasm. Rev is continuously...
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Transporter Classification Database (category Protein classification)
Human immunodeficiency virus type I Vpu channel family 1.A.41 Avian reovirus p10 Vvroporin family 1.A.42 HIV viral protein R family 1.A.43 Camphor resistance...
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National Library of Medicine (NLM). This list covers DNA-binding proteins. For other protein-related codes, see List of MeSH codes (D12.776). Codes before...
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display many of the attributes of HIV-1 accessory gene products such as Vpr, Vpu or Nef.[citation needed] Among these subtypes, genetic sequences are mostly...
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term "visual processing unit" or VPU with the release of the Radeon 9700 in 2002. The AMD Alveo MA35D features dual VPU’s, each using the 5 nm process in...
84 KB (8,457 words) - 06:15, 20 August 2024
vpr, vif, vpu/vpx Structural proteins (envelope): SU, TM(gag): MA, CA, NC Enzymes: RT, PR, IN Gene regulators: Tat, Rev Accessory proteins: Nef, Vpr,...
35 KB (3,270 words) - 14:13, 27 July 2024
Immunoevasin (category Viral protein class)
lysosomes from trans-Golgi. Nef and Vpu proteins can also direct CD4 co-receptor for lysosomal (Nef) or cytosolic proteasomal (Vpu) degradation, affecting the...
12 KB (1,219 words) - 15:11, 27 August 2023
Strebel K, Benarous R (March 1998). "A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through...
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EID1 (category Protein stubs)
Bour SP, Durand H, et al. (1998). "A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through...
5 KB (629 words) - 17:36, 27 November 2023