• Thumbnail for Vpu protein
    Vpu is an accessory protein that in HIV is encoded by the vpu gene. Vpu stands for "Viral Protein U". The Vpu protein acts in the degradation of CD4 in...
    11 KB (1,419 words) - 04:26, 15 April 2024
  • Thumbnail for Endoplasmic-reticulum-associated protein degradation
    target for ERAD. However, HIV produces the membrane protein Vpu that binds to CD4. The Vpu protein mainly retains the CD4 in the ER by SCFβ-TrCP-dependent...
    13 KB (1,709 words) - 07:49, 27 July 2024
  • vision tasks Viral protein U (Vpu), a regulatory protein found in HIV-1 Vancouver Police Union, a trade union in Canada Search for "vpu" on Wikipedia. All...
    940 bytes (133 words) - 07:06, 2 March 2024
  • (November 2001). "The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent...
    854 bytes (100 words) - 00:36, 6 June 2016
  • vpu (Virus protein U) - Vpu is specific to HIV-1. It is a class I oligomeric integral membrane phosphoprotein with numerous biological functions. Vpu...
    33 KB (3,936 words) - 19:54, 3 July 2024
  • Thumbnail for HIV
    class I and class II molecules. Nef also interacts with SH3 domains. The vpu protein (p16) influences the release of new virus particles from infected cells...
    125 KB (14,365 words) - 18:21, 14 August 2024
  • Thumbnail for CSNK2B
    CSNK2B (category Protein domains)
    (1996). "The human immunodeficiency virus type 1 Vpu protein: a potential regulator of proteolysis and protein transport in the mammalian secretory pathway"...
    19 KB (2,258 words) - 05:41, 19 February 2024
  • Thumbnail for Ubiquitin
    Ubiquitin (category Protein structure)
    JS (April 2010). "Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps". PLOS Pathogens...
    98 KB (11,068 words) - 18:53, 17 August 2024
  • non-structural proteins, named Viral Protein U (Vpu) and Viral Protein R (Vpr), part of a new class of retroviral proteins – designated accessory proteins – that...
    18 KB (1,491 words) - 23:27, 23 July 2024
  • Thumbnail for Host switch
    SIVs use the Nef protein to remove tetherin from the cell membrane whereas HIV-1 uses the Vpu protein degrade the defence protein. Tetherin is a conserved...
    31 KB (3,863 words) - 12:36, 25 January 2024
  • Accessory proteins: Nef: negative factor Vpr: regulatory protein Vif: APOBEC3 inhibitor Vpu/Vpx: unique to each type of HIV p6: part of gag Serological...
    16 KB (1,770 words) - 21:42, 20 July 2024
  • Thumbnail for CD4
    CD4 (category Protein domains)
    Pacyniak E, Gomez LM, Gomez ML, Stephens EB (July 2004). "Vpu: a multifunctional protein that enhances the pathogenesis of human immunodeficiency virus...
    22 KB (2,581 words) - 20:03, 21 June 2024
  • Thumbnail for Tetherin
    HIV-1 overcomes this restriction through vpu. Vpu interacts with tetherin by interacting with the protein at its transmembrane domain and recruiting...
    20 KB (2,458 words) - 23:57, 29 August 2023
  • Thumbnail for VP40
    VP40 (redirect from Vp40 protein domain)
    In molecular biology, VP40 is the name of a viral matrix protein. Most commonly, it is found in the Ebola virus (EBOV), a type of non-segmented, negative-strand...
    7 KB (732 words) - 14:30, 24 August 2024
  • Thumbnail for Viroporin
    Viroporin (category Viral protein class)
    established functional effects exerted through protein-protein interactions. For example, the HIV-1 viroporin Vpu promotes viral budding through interactions...
    20 KB (1,967 words) - 00:33, 29 November 2023
  • Thumbnail for P24 capsid protein
    capsid protein is the most abundant HIV protein with each virus containing approximately 1,500 to 3,000 p24 molecules. It is the major structural protein within...
    13 KB (1,461 words) - 20:04, 15 May 2024
  • Thumbnail for SGTA
    (December 2001). "Association of Vpu-binding protein with microtubules and Vpu-dependent redistribution of HIV-1 Gag protein". Virology. 291 (2): 198–207...
    11 KB (1,210 words) - 21:22, 23 December 2023
  • Vpx (redirect from Vpx (Viral Protein))
    structure to the protein Vpr that is carried by SIV and HIV-2 as well as HIV-1. Vpx is one of five accessory proteins (Vif, Vpx, Vpr, Vpu, and Nef) carried...
    6 KB (668 words) - 01:52, 19 August 2023
  • Thumbnail for BCL2-related protein A1
    S, et al. (2001). "The human immunodeficiency virus type 1 accessory protein Vpu induces apoptosis by suppressing the nuclear factor kappaB-dependent...
    11 KB (1,410 words) - 15:45, 23 December 2023
  • HIV-1 accessory protein Vpu. Subsequently, another inhibitor of HIV-1 replication was discovered in his lab, Mx2, a cellular protein shown to inhibit...
    10 KB (989 words) - 02:39, 23 May 2024
  • Thumbnail for BTRC (gene)
    identified as a cellular ubiquitin ligase that is bound by the HIV-1 Vpu viral protein to eliminate cellular CD4 by connecting it to the proteolytic machinery...
    28 KB (3,356 words) - 01:22, 22 March 2024
  • Thumbnail for Rev (HIV)
    Rev (HIV) (category Viral regulatory and accessory proteins)
    unspliced gag and pol transcripts and incompletely spliced env, vif, vpr and vpu transcripts at the RRE, facilitating export to the cytoplasm. Rev is continuously...
    25 KB (3,100 words) - 04:44, 3 December 2023
  • Transporter Classification Database (category Protein classification)
    Human immunodeficiency virus type I Vpu channel family 1.A.41 Avian reovirus p10 Vvroporin family 1.A.42 HIV viral protein R family 1.A.43 Camphor resistance...
    38 KB (5,159 words) - 15:41, 17 April 2024
  • National Library of Medicine (NLM). This list covers DNA-binding proteins. For other protein-related codes, see List of MeSH codes (D12.776). Codes before...
    27 KB (972 words) - 19:42, 9 December 2023
  • Thumbnail for Feline immunodeficiency virus
    display many of the attributes of HIV-1 accessory gene products such as Vpr, Vpu or Nef.[citation needed] Among these subtypes, genetic sequences are mostly...
    42 KB (4,962 words) - 21:30, 21 June 2024
  • Thumbnail for Graphics processing unit
    term "visual processing unit" or VPU with the release of the Radeon 9700 in 2002. The AMD Alveo MA35D features dual VPU’s, each using the 5 nm process in...
    84 KB (8,457 words) - 06:15, 20 August 2024
  • Thumbnail for Simian immunodeficiency virus
    vpr, vif, vpu/vpx Structural proteins (envelope): SU, TM(gag): MA, CA, NC Enzymes: RT, PR, IN Gene regulators: Tat, Rev Accessory proteins: Nef, Vpr,...
    35 KB (3,270 words) - 14:13, 27 July 2024
  • Immunoevasin (category Viral protein class)
    lysosomes from trans-Golgi. Nef and Vpu proteins can also direct CD4 co-receptor for lysosomal (Nef) or cytosolic proteasomal (Vpu) degradation, affecting the...
    12 KB (1,219 words) - 15:11, 27 August 2023
  • Thumbnail for S-phase kinase-associated protein 1
    Strebel K, Benarous R (March 1998). "A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through...
    17 KB (2,137 words) - 22:51, 11 April 2024
  • Thumbnail for EID1
    EID1 (category Protein stubs)
    Bour SP, Durand H, et al. (1998). "A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through...
    5 KB (629 words) - 17:36, 27 November 2023