• classification, a Z-type ligand refers to a ligand that accepts two electrons from the metal center. This is in contrast to X-type ligands, which form a bond...
    9 KB (1,102 words) - 15:15, 23 February 2023
  • Thumbnail for Ligand
    In coordination chemistry, a ligand is an ion or molecule with a functional group that binds to a central metal atom to form a coordination complex. The...
    35 KB (3,307 words) - 12:53, 22 September 2024
  • classes of ligands are respectively given the symbols L, X, and Z. The method was published by Malcolm L. H. Green in 1995. X-type ligands are those that...
    6 KB (734 words) - 09:09, 9 January 2024
  • Ligand field theory (LFT) describes the bonding, orbital arrangement, and other characteristics of coordination complexes. It represents an application...
    13 KB (1,581 words) - 05:06, 18 June 2024
  • Thumbnail for Hill equation (biochemistry)
    equations that reflect the binding of ligands to macromolecules, as a function of the ligand concentration. A ligand is "a substance that forms a complex...
    30 KB (3,330 words) - 13:07, 4 October 2024
  • Thumbnail for Ligand (biochemistry)
    In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose. The etymology stems from...
    29 KB (3,166 words) - 21:19, 21 August 2024
  • Thumbnail for Ligand-gated ion channel
    Ligand-gated ion channels (LICs, LGIC), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open...
    29 KB (2,597 words) - 03:43, 7 April 2024
  • transformation. Redox non-innocent behavior of ligands is illustrated by nickel bis(stilbenedithiolate) ([Ni(S2C2Ph2)2]z). As all bis(1,2-dithiolene) complexes...
    15 KB (1,728 words) - 12:20, 31 January 2024
  • complexes are coordination compounds containing metal ions with only water as a ligand. These complexes are the predominant species in aqueous solutions of many...
    15 KB (1,551 words) - 19:45, 27 October 2024
  • Thumbnail for Docking (molecular)
    which predicts the preferred orientation of one molecule to a second when a ligand and a target are bound to each other to form a stable complex. Knowledge...
    33 KB (3,935 words) - 01:22, 28 October 2024
  • Thumbnail for Coordination complex
    polydentate (multiple bonded) ligand is a molecule or ion that bonds to the central atom through several of the ligand's atoms; ligands with 2, 3, 4 or even 6...
    57 KB (5,553 words) - 04:29, 2 October 2024
  • A ligand binding assay (LBA) is an assay, or an analytic procedure, which relies on the binding of ligand molecules to receptors, antibodies or other...
    33 KB (4,118 words) - 10:39, 17 October 2024
  • Thumbnail for Drug design
    Drug design (redirect from Ligand design)
    of protein-ligand complexes". Journal of Chemical Information and Modeling. 46 (1): 380–391. doi:10.1021/ci050283k. PMID 16426072. Deng Z, Chuaqui C,...
    44 KB (5,022 words) - 08:47, 12 October 2024
  • Thumbnail for PD-L1
    Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by...
    25 KB (3,052 words) - 15:34, 14 September 2024
  • equation for determining ligand bond number is as follows: LBN = L + X + Z Where L represents the number of neutral ligands adding two electrons to the...
    5 KB (475 words) - 00:48, 28 June 2021
  • Thumbnail for Nuclear receptor
    receptors often occurs in the presence of a ligand—a molecule that affects the receptor's behavior. Ligand binding to a nuclear receptor results in a conformational...
    74 KB (6,683 words) - 09:55, 12 September 2024
  • Thumbnail for Diphosphine ligands
    are organophosphorus compounds most commonly used as bidentate phosphine ligands in inorganic and organometallic chemistry. They are identified by the presence...
    10 KB (819 words) - 04:22, 10 September 2024
  • Thumbnail for Cis–trans isomerism
    metal atom, and X and Y are two different types of ligands.) In the cis isomer, the two Y ligands are adjacent to each other at 90°, as is true for the...
    16 KB (1,739 words) - 01:08, 5 August 2024
  • Thumbnail for RANKL
    RANKL (redirect from RANK Ligand)
    Receptor activator of nuclear factor kappa-Β ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced...
    28 KB (3,309 words) - 05:21, 5 August 2024
  • Thumbnail for Trans-spanning ligand
    Trans-spanning ligands are bidentate ligands that can span opposite sites of a complex with square-planar geometry. A wide variety of ligands that chelate...
    3 KB (393 words) - 22:51, 27 March 2024
  • 3COCHCOCH− 3) and metal ions, usually transition metals. The bidentate ligand acetylacetonate is often abbreviated acac. Typically both oxygen atoms bind...
    25 KB (2,762 words) - 21:04, 12 August 2024
  • Thumbnail for Inverted ligand field theory
    Inverted ligand field theory (ILFT) describes a phenomenon in the bonding of coordination complexes where the lowest unoccupied molecular orbital is primarily...
    26 KB (2,935 words) - 12:44, 22 September 2024
  • Thumbnail for Pharmacodynamics
    {\displaystyle {\ce {L + R <=> LR}}} where L, R, and LR represent ligand (drug), receptor, and ligand-receptor complex concentrations, respectively. This equation...
    19 KB (2,225 words) - 21:08, 29 May 2024
  • Thumbnail for Allosteric regulation
    directly to an enzyme's active site or the binding site of the endogenous ligand of a receptor are called orthosteric regulators or modulators. The site...
    37 KB (4,422 words) - 05:12, 29 September 2024
  • Thumbnail for Guggulsterone
    therapeutics for the treatment of COVID-19. Guggulsterone is a broad-spectrum ligand of steroid hormone receptors, and is known to possess the following activities:...
    7 KB (505 words) - 18:43, 20 October 2024
  • R.; Zhou, Z.; Chan, A. S. C. (2006). "A New Class of Versatile Chiral-Bridged Atropisomeric Diphosphine Ligands: Remarkably Efficient Ligand Syntheses...
    64 KB (6,355 words) - 10:03, 21 August 2024
  • Thumbnail for Sodium channel
    at Nodes of Ranvier in developing neurons. Ligand-gated sodium channels are activated by binding of a ligand instead of a change in membrane potential...
    51 KB (5,600 words) - 16:44, 18 September 2024
  • Thumbnail for Hydroxide
    mixed-ligand complexes of the type [MLx(OH)y]z+, where L is a ligand. The hydroxide ion often serves as a bridging ligand, donating one pair of electrons to each...
    41 KB (4,891 words) - 13:03, 26 August 2024
  • diene is a useful precursor to other organic compounds and serves as a ligand in organometallic chemistry. It is a colorless liquid with a strong odor...
    13 KB (1,002 words) - 14:43, 28 August 2024
  • Thumbnail for Metal carbonyl
    carbonyls are coordination complexes of transition metals with carbon monoxide ligands. Metal carbonyls are useful in organic synthesis and as catalysts or catalyst...
    70 KB (7,931 words) - 06:04, 29 May 2024