biochemistry, a zymogen (/ˈzaɪmədʒən, -moʊ-/), also called a proenzyme (/ˌproʊˈɛnzaɪm/), is an inactive precursor of an enzyme. A zymogen requires a biochemical...

The difference between zymogens and the activated enzymes lies in the fact that the active site for catalysis of the zymogens is distorted. As a result...

purified from human skin (1968), and was recognized to be synthesized as a zymogen. The "cysteine switch" was described in 1990. The MMPs have a common domain...

phenylalanine and tryptophan increase the probability of cleavage. Pepsin's zymogen (proenzyme), pepsinogen, is released by the gastric chief cells in the...

proteins and hormones are synthesized in the form of their precursors - zymogens, proenzymes, and prehormones. These proteins are cleaved to form their...

in the blood clotting is the initiation of thrombin formation from the zymogen prothrombin. Thromboplastin defines the cascade that leads to the activation...

Suzuki M, Okabayashi K, Takahashi E (Jun 1998). "Assignment of pancreatic zymogen granule membrane protein GP2 (GP2) to human chromosome band 9q21.11 to...

fibrin is termed fibrinolysis. In humans, the plasmin protein (in the zymogen form of plasminogen) is encoded by the PLG gene. Plasmin is a serine protease...

Factor XI, or plasma thromboplastin antecedent, is the zymogen form of factor XIa, one of the enzymes involved in coagulation. Like many other coagulation...

cells called "chief cells" in its inactive form pepsinogen, which is a zymogen. Pepsinogen is then activated by the stomach acid into its active form...

surface. Chief cells (zymogen cells/peptic cells) – They are found in the basal regions of the gland and release proenzymes or zymogens – pepsinogen (precursor...

walls. The cells of each acinus secrete inactive digestive enzymes called zymogens into the small intercalated ducts which they surround. In each acinus,...

known as autoprothrombin IIA and blood coagulation factor XIV,: 6822  is a zymogen, that is, an inactive enzyme. The activated form plays an important role...

originally believed those substances to be precursors of antibodies, just as a zymogen is a precursor of an enzyme. But, by 1903, he understood that an antigen...

extramitochondrial locations. In pancreatic acinar tissue, these subunits were found in zymogen granules. Additionally, in the anterior pituitary, relatively high amounts...

Hageman factor, is a plasma protein involved in coagulation. It is the zymogen form of factor XIIa (EC 3.4.21.38), an enzyme of the serine protease (or...

Trypsinogen (/ˌtrɪpˈsɪnədʒən, -ˌdʒɛn/) is the precursor form (or zymogen) of trypsin, a digestive enzyme. It is produced by the pancreas and found in...

that catalyze the activation of plasmin via proteolytic cleavage of its zymogen form plasminogen. Plasmin is an important factor in fibrinolysis, the breakdown...

(extrinsic) pathway. The pathways are a series of reactions, in which a zymogen (inactive enzyme precursor) of a serine protease and its glycoprotein co-factor...

Iwanaga S (February 1986). "Lipopolysaccharide-sensitive serine-protease zymogen (factor C) found in Limulus hemocytes. Isolation and characterization"...

produce, release, or convert trypsinogen—an inactive enzyme precursor or zymogen—muscle fibres are not properly digested and are therefore released in the...

amino acids are exposed. Gastric HCl simultaneously cleaves pepsinogen, a zymogen, into active pepsin, an endopeptidase that advances the digestive process...

JCLN1, MGC183567, MGC34820, ZG16A, zymogen granule membrane protein 16, zymogen granule protein 16 homolog, and zymogen granule protein. The gene is located...

crystal structure, comparison with alpha-chymotrypsin, and implications for zymogen activation". Biochemistry. 9 (9): 1997–2009. doi:10.1021/bi00811a022. PMID 5442169...

digestion in humans and other animals. Enteropeptidase converts trypsinogen (a zymogen) into its active form trypsin, resulting in the subsequent activation of...

enters the gut. This type of inactive precursor to an enzyme is known as a zymogen: 149–53  or proenzyme. Enzyme production (transcription and translation...

protein–protein interactions. A special case of protein enzyme inhibitors are zymogens that contain an autoinhibitory N-terminal peptide that binds to the active...

physiological substrate of this enzyme is plasminogen, which is an inactive form (zymogen) of the serine protease plasmin. Activation of plasmin triggers a proteolytic...

endopeptidase activity cornification zymogen activation regulation of lipoprotein lipase activity dibasic protein processing zymogen inhibition positive regulation...

pituitary, strong and specific presence of cytochrome c was detected in zymogen granules and in growth hormone granules, respectively. In the pancreas...