• Thumbnail for Low-density lipoprotein
    Low-density lipoprotein (LDL) is one of the five major groups of lipoprotein that transport all fat molecules around the body in extracellular water. These...
    62 KB (6,980 words) - 04:34, 24 March 2025
  • major groups of lipoproteins (chylomicrons, VLDL, intermediate-density lipoprotein, low-density lipoprotein, high-density lipoprotein) that enable fats...
    6 KB (750 words) - 20:18, 6 April 2024
  • Thumbnail for Lipoprotein(a)
    Lipoprotein(a) is a low-density lipoprotein variant containing a protein called apolipoprotein(a). Genetic and epidemiological studies have identified...
    45 KB (5,489 words) - 17:20, 31 March 2025
  • Intermediate-density lipoproteins (IDLs) belong to the lipoprotein particle family and are formed from the degradation of very low-density lipoproteins as well...
    3 KB (402 words) - 03:15, 31 March 2023
  • High-density lipoprotein (HDL) is one of the five major groups of lipoproteins. Lipoproteins are complex particles composed of multiple proteins which...
    51 KB (5,473 words) - 19:14, 3 April 2025
  • Thumbnail for Lipoprotein lipase
    that hydrolyzes triglycerides in lipoproteins, such as those found in chylomicrons and very low-density lipoproteins (VLDL), into two free fatty acids...
    33 KB (4,021 words) - 02:22, 3 July 2024
  • Thumbnail for LRP1
    Low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster...
    32 KB (3,450 words) - 20:21, 5 December 2024
  • Thumbnail for LDL receptor
    The low-density lipoprotein receptor (LDL-R) is a mosaic protein of 839 amino acids (after removal of 21-amino acid signal peptide) that mediates the...
    28 KB (3,040 words) - 04:11, 7 April 2025
  • Thumbnail for Lipoprotein
    Very-low-density lipoproteins (VLDL) carry (newly synthesised) triglycerides from the liver to adipose tissue. Intermediate-density lipoproteins (IDL)...
    23 KB (2,605 words) - 13:01, 16 March 2025
  • enzymology, a low-density-lipoprotein receptor kinase (EC 2.7.11.29) is an enzyme that catalyzes the chemical reaction ATP + [low-density-lipoprotein receptor]-L-serine...
    2 KB (228 words) - 14:47, 26 August 2023
  • Thumbnail for PCSK9
    tissues and cell types. PCSK9 binds to and degrades the receptor for low-density lipoprotein particles (LDL), which typically transport 3,000 to 6,000 fat molecules...
    69 KB (7,354 words) - 22:21, 10 January 2025
  • brand name Leqvio, is a medication used for the treatment of high low-density lipoprotein (LDL) cholesterol and for the treatment of people with atherosclerotic...
    21 KB (1,744 words) - 14:15, 24 April 2024
  • Thumbnail for Apolipoprotein B
    remnant, where it is endocytosed and degraded. Very low-density lipoproteins and low-density lipoproteins interfere with the quorum sensing system that upregulates...
    40 KB (4,892 words) - 01:14, 13 March 2025
  • Thumbnail for Low-density lipoprotein receptor gene family
    The low-density lipoprotein receptor gene family codes for a class of structurally related cell surface receptors that fulfill diverse biological functions...
    7 KB (701 words) - 03:09, 15 September 2024
  • Thumbnail for Hypercholesterolemia
    (lipoproteins). Lipoproteins are classified by their density: very low density lipoprotein (VLDL), intermediate density lipoprotein (IDL), low density...
    61 KB (6,213 words) - 00:05, 12 February 2025
  • Thumbnail for Cholesterol
    Elevated levels of cholesterol in the blood, especially when bound to low-density lipoprotein (LDL, often referred to as "bad cholesterol"), may increase the...
    81 KB (8,775 words) - 01:11, 13 March 2025
  • Thumbnail for Apolipoprotein C-III
    intestine, and is found on triglyceride-rich lipoproteins such as chylomicrons, very low density lipoprotein (VLDL), and remnant cholesterol. ApoC-III is...
    20 KB (2,509 words) - 16:05, 30 October 2024
  • Thumbnail for Low-density lipoprotein receptor-related protein 4
    Low-density lipoprotein receptor-related protein 4 (LRP-4), also known as multiple epidermal growth factor-like domains 7 (MEGF7), is a protein that in...
    5 KB (637 words) - 13:05, 18 August 2023
  • Thumbnail for VLDL receptor
    The very-low-density-lipoprotein receptor (VLDLR) is a transmembrane lipoprotein receptor of the low-density-lipoprotein (LDL) receptor family. VLDLR...
    37 KB (4,736 words) - 15:31, 20 February 2025
  • Thumbnail for Apolipoprotein E
    of lipoprotein particles, including chylomicron remnants, VLDL, IDL, and some HDL. Apo-E interacts significantly with the low-density lipoprotein receptor...
    58 KB (6,576 words) - 04:41, 22 March 2025
  • Lipoprotein-X (Lp-X) is an abnormal low density lipoprotein found in cholestasis. Lipoprotein-X is a lamellar particle of 30 to 70 nm in diameter as revealed...
    4 KB (426 words) - 08:00, 7 April 2025
  • Lipoprotein receptor-related proteins, low density lipoprotein receptor-related proteins (HGNC) or prolow-density lipoprotein receptor-related protein...
    751 bytes (63 words) - 10:27, 17 September 2023
  • Thumbnail for Low-density lipoprotein receptor-related protein 8
    Low-density lipoprotein receptor-related protein 8 (LRP8), also known as apolipoprotein E receptor 2 (ApoER2), is a protein that in humans is encoded...
    27 KB (3,439 words) - 10:00, 27 March 2024
  • body] A lipid profile report typically includes: Low-density lipoprotein (LDL) High-density lipoprotein (HDL) Total triglycerides Total cholesterol LDL...
    16 KB (1,683 words) - 15:22, 7 April 2025
  • Thumbnail for Lipoprotein-associated phospholipase A2
    blood, Lp-PLA2 travels mainly with low-density lipoprotein (LDL). Less than 20% is associated with high-density lipoprotein (HDL). Several lines of evidence...
    12 KB (1,378 words) - 21:36, 20 September 2024
  • Thumbnail for Atherosclerosis
    endothelial cells of the vessel wall associated with retained low-density lipoprotein (LDL) particles. This retention may be a cause, an effect, or both...
    103 KB (11,213 words) - 16:53, 12 April 2025
  • Thumbnail for Atorvastatin
    decreases de novo cholesterol synthesis, increasing expression of low-density lipoprotein receptors (LDL receptors) on hepatocytes. This increases LDL uptake...
    101 KB (9,550 words) - 18:48, 1 March 2025
  • Thumbnail for Low-density lipoprotein receptor adapter protein 1
    Low-density lipoprotein receptor adapter protein 1 is a protein that in humans is encoded by the LDLRAP1 gene. The protein encoded by this gene is a cytosolic...
    9 KB (1,118 words) - 09:21, 24 December 2023
  • Thumbnail for OLR1
    Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) also known as lectin-type oxidized LDL receptor 1 (LOX-1) is a protein that in humans...
    12 KB (1,521 words) - 00:29, 3 December 2023
  • Thumbnail for Foam cell
    fat-laden cells with a M2 macrophage-like phenotype. They contain low density lipoproteins (LDL) and can be rapidly detected by examining a fatty plaque under...
    17 KB (2,058 words) - 15:46, 23 September 2024