• Thumbnail for Paclitaxel
    Paclitaxel, sold under the brand name Taxol among others, is a chemotherapy medication used to treat ovarian cancer, esophageal cancer, breast cancer,...
    61 KB (6,550 words) - 11:33, 17 August 2024
  • Protein-bound paclitaxel, also known as nanoparticle albumin–bound paclitaxel or nab-paclitaxel, is an injectable formulation of paclitaxel used to treat...
    9 KB (716 words) - 09:40, 4 August 2024
  • Thumbnail for DHA-paclitaxel
    DHA-paclitaxel (or Taxoprexin) is an investigational drug (from Protarga Inc) made by linking paclitaxel to docosahexaenoic acid (DHA), a fatty acid that...
    5 KB (225 words) - 17:23, 30 April 2023
  • Thumbnail for Paclitaxel total synthesis
    Paclitaxel total synthesis in organic chemistry is a major ongoing research effort in the total synthesis of paclitaxel (Taxol). This diterpenoid is an...
    16 KB (1,961 words) - 04:43, 8 August 2024
  • Thumbnail for Paclitaxel trevatide
    Paclitaxel trevatide (development codes NG1005 and GRN1005) is an experimental chemotherapy drug that is under development by Angiochem Inc, a Canadian...
    15 KB (1,252 words) - 03:07, 17 November 2023
  • Thumbnail for Atezolizumab
    of the drug with nab-paclitaxel on people with advanced TNBC concluded. Atezolizumab, in combination with bevacizumab, paclitaxel, and carboplatin, was...
    43 KB (4,164 words) - 02:04, 16 July 2024
  • Thumbnail for Docetaxel
    severe adverse effects. Docetaxel and paclitaxel have comparable efficacy metastatic breast cancer but paclitaxel has less severe side effects. Additionally...
    44 KB (4,623 words) - 22:26, 10 May 2024
  • Thumbnail for Taxus
    source of paclitaxel. Other yew species contain similar compounds with similar biochemical activity. Docetaxel, an analogue of paclitaxel, is derived...
    26 KB (2,514 words) - 01:40, 31 July 2024
  • S. Food and Drug Administration approved protein-bound paclitaxel (also known as nab-paclitaxel, sold as Abraxane) used with gemcitabine. This regimen...
    7 KB (711 words) - 16:46, 29 April 2024
  • Pirarubicin Valrubicin Zorubicin Abraxane Cabazitaxel Docetaxel Larotaxel Paclitaxel Taxotere Tesetaxel Ixabepilone Entinostat Romidepsin Vorinostat Zabadinostat...
    5 KB (324 words) - 12:07, 20 July 2024
  • anticancer drug paclitaxel (Taxol). The incorporation of the C10 precursor verbenone, a member of the chiral pool, makes the production of paclitaxel more efficient...
    5 KB (515 words) - 11:57, 6 September 2023
  • albumin-bound paclitaxel. Paclitaxel Paclitaxel binds to tubulin and stabilizes the microtubules which leads to inhibition of cell division. Paclitaxel is provided...
    59 KB (6,487 words) - 18:42, 27 December 2023
  • An example of a drug-eluting stent. This is the TAXUS Express2 Paclitaxel-Eluting Coronary Stent System, which releases paclitaxel....
    58 KB (7,309 words) - 05:04, 7 July 2024
  • Thumbnail for Mitotic inhibitor
    mitotic inhibitors frequently used in the treatment of cancer include paclitaxel, docetaxel, vinblastine, vincristine, and vinorelbine. Colchicine and...
    59 KB (6,992 words) - 22:40, 13 August 2024
  • PXL may refer to: PXL-2000, camcorder Paclitaxel, drug PCL 6 Enhanced, printer command language This disambiguation page lists articles associated with...
    178 bytes (46 words) - 20:15, 29 December 2019
  • the results of the RAINBOW trial, that compared ramucirumab plus paclitaxel or paclitaxel alone. In December 2014, the FDA approved ramucirumab in combination...
    14 KB (1,302 words) - 07:55, 1 July 2024
  • Thumbnail for Small-cell carcinoma
    be sensitive to paclitaxel and 66.7% of paclitaxel-resistant cells to cisplatin. The mechanism for this activity is unknown. Paclitaxel-based chemotherapy...
    54 KB (5,529 words) - 09:35, 4 August 2024
  • Thumbnail for Cinnamon
    (wintergreen) N-Methylmaleimide Nicotine (tobacco) Oleocanthal (olive oil) Paclitaxel (Pacific yew) Paracetamol (acetaminophen) PF-4840154 Phenacyl chloride...
    47 KB (5,257 words) - 00:03, 17 August 2024
  • Thumbnail for Limonene
    Forskolin Manoyl oxide Pimaral Pimarol Tetracyclic Aphidicolin Gibberellin Paclitaxel Resin acids Abietic acid Communic acid Dehydroabietic acid Isopimaric...
    19 KB (1,534 words) - 12:36, 2 August 2024
  • Thumbnail for Taxane
    from plants of the genus Taxus (yews), and feature a taxadiene core. Paclitaxel (Taxol) and docetaxel (Taxotere) are widely used as chemotherapy agents...
    7 KB (589 words) - 14:09, 24 April 2024
  • Thumbnail for Taccalonolide
    cancer cells from dividing by interfering with tubulin. While taxanes like Paclitaxel and docetaxel have been used successfully against breast, ovarian, prostate...
    8 KB (1,086 words) - 00:13, 3 August 2024
  • Thumbnail for Rosemary
    (wintergreen) N-Methylmaleimide Nicotine (tobacco) Oleocanthal (olive oil) Paclitaxel (Pacific yew) Paracetamol (acetaminophen) PF-4840154 Phenacyl chloride...
    27 KB (2,799 words) - 17:50, 18 August 2024
  • Thumbnail for Polyglutamic acid
    Alpha PGA is used as a delivery aid for paclitaxel, an anticancer drug, under the generic name of paclitaxel poliglumex. Research is underway for its...
    9 KB (1,003 words) - 21:02, 23 January 2024
  • Thumbnail for Halozyme
    Hyaluronidase (PEGPH20) in Combination With Nab-Paclitaxel Plus Gemcitabine Compared With Placebo Plus Nab-Paclitaxel and Gemcitabine in Subjects With Hyaluronan-High...
    11 KB (1,003 words) - 00:57, 11 August 2024
  • Thumbnail for Natural product
    phenylalanine and tryptophan. Paclitaxel, in contrast, is a tubulin polymerization stabilizer and is used as a chemotherapeutic drug. Paclitaxel is based on the terpenoid...
    88 KB (9,571 words) - 23:47, 31 March 2024
  • Thumbnail for Ovarian cancer
    include paclitaxel, cisplatin, topotecan, doxorubicin, epirubicin, and gemcitabine. Carboplatin is typically given in combination with either paclitaxel or...
    197 KB (21,104 words) - 09:24, 12 August 2024
  • Thumbnail for Buparlisib
    effects. The phase II/III trial BELLE-4 compared buparlisib + paclitaxel with paclitaxel alone in patients with advanced or metastatic HER2-negative breast...
    8 KB (690 words) - 22:44, 5 August 2024
  • semisynthesis include the early commercial production of the anti-cancer agent paclitaxel from 10-deacetylbaccatin isolated from the needles of Taxus baccata (European...
    6 KB (679 words) - 16:25, 31 January 2024
  • Thumbnail for Non-small-cell lung cancer
    Oncology Group study that found that adding bevacizumab to carboplatin and paclitaxel chemotherapy for certain patients with recurrent or advanced NSCLC (stage...
    50 KB (5,300 words) - 12:47, 16 August 2024
  • adjuvant therapy may consist of chemotherapy (doxorubicin, trastuzumab, paclitaxel, docetaxel, cyclophosphamide, fluorouracil, and methotrexate) and radiotherapy...
    40 KB (4,808 words) - 04:21, 1 July 2024