• The Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through cell surface receptors...
    63 KB (7,427 words) - 14:51, 9 July 2024
  • Thumbnail for Paracrine signaling
    cellular biology, paracrine signaling is a form of cell signaling, a type of cellular communication in which a cell produces a signal to induce changes in nearby...
    46 KB (4,967 words) - 21:12, 7 July 2024
  • de-regulated Wnt signaling pathway reduces proliferation and survival of cancer. These findings suggest that interference with Wnt signaling at the ligand-receptor...
    18 KB (2,105 words) - 17:15, 1 December 2023
  • A biochemical cascade, also known as a signaling cascade or signaling pathway, is a series of chemical reactions that occur within a biological cell when...
    99 KB (11,432 words) - 18:01, 29 April 2024
  • Thumbnail for Apc, wnt signaling pathway regulator
    APC, WNT signaling pathway regulator is a protein that in humans is encoded by the APC gene. This gene encodes a tumor suppressor protein that acts as...
    4 KB (617 words) - 19:39, 29 February 2024
  • signalling pathway PI3K/AKT/mTOR signalling pathway TGF beta signalling pathway TLR signalling pathway VEGF signalling pathway Wnt signalling pathway...
    1,014 bytes (86 words) - 23:23, 19 January 2023
  • Thumbnail for Sonic hedgehog protein
    Muroyama Y, Fujihara M, Ikeya M, Kondoh H, Takada S (March 2002). "Wnt signaling plays an essential role in neuronal specification of the dorsal spinal...
    62 KB (7,240 words) - 05:28, 10 July 2024
  • The Akt signaling pathway or PI3K-Akt signaling pathway is a signal transduction pathway that promotes survival and growth in response to extracellular...
    37 KB (4,145 words) - 08:04, 3 July 2024
  • WNT or Wnt may refer to: Windows NT WNT (Women's National Team) Wnt signaling pathway, a complex protein network The Weymouth New Testament (1902), translation...
    655 bytes (109 words) - 16:27, 22 December 2021
  • The Hedgehog signaling pathway is a signaling pathway that transmits information to embryonic cells required for proper cell differentiation. Different...
    59 KB (6,895 words) - 22:30, 25 April 2024
  • Thumbnail for Catenin beta-1
    Catenin beta-1 (category Signal transduction)
    cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous...
    107 KB (12,362 words) - 22:48, 10 July 2024
  • Thumbnail for WNT3A
    with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathway". The Journal of Biological Chemistry. 279 (17): 17535–42. doi:10...
    15 KB (1,660 words) - 03:27, 6 January 2024
  • Thumbnail for LRP6
    protein family members for transducing signals by Wnt proteins through the canonical Wnt pathway. Canonical WNT signals are transduced through Frizzled receptor...
    11 KB (1,411 words) - 12:13, 4 April 2024
  • Thumbnail for TCF/LEF family
    a SOX-like high mobility group domain. They are involved in the Wnt signaling pathway, particularly during embryonic and stem-cell development, but also...
    17 KB (2,038 words) - 15:13, 11 December 2023
  • Thumbnail for Dishevelled
    is a family of proteins involved in canonical and non-canonical Wnt signalling pathways. Dsh (Dvl in mammals) is a cytoplasmic phosphoprotein that acts...
    12 KB (1,387 words) - 17:01, 8 June 2024
  • Thumbnail for Hippo signaling pathway
    The Hippo signaling pathway, also known as the Salvador-Warts-Hippo (SWH) pathway, is a signaling pathway that controls organ size in animals through...
    28 KB (3,241 words) - 04:58, 19 June 2024
  • Thumbnail for Protein Wnt-5a
    mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling". Molecular and Cellular Biology. 23 (1): 131–9...
    29 KB (3,404 words) - 03:05, 11 July 2024
  • Thumbnail for Proto-oncogene Wnt-1
    another family member, WNT10B, in the chromosome 12q13 region. Wnt signaling pathway GRCh38: Ensembl release 89: ENSG00000125084 – Ensembl, May 2017...
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  • Thumbnail for Presenilin-1
    collectively suggest a critical role of presenilin 1 in the Notch signaling pathway. Wnt signaling pathway has been shown to be involved in several critical steps...
    25 KB (3,113 words) - 11:23, 31 December 2023
  • Thumbnail for LRP5
    Reduction of canonical Wnt signals upon depletion of LRP5 and LRP6 results in p120-catenin degradation. The Wnt signaling pathway was first linked to bone...
    24 KB (3,205 words) - 21:15, 27 March 2024
  • Thumbnail for Notch signaling pathway
    The Notch signaling pathway is a highly conserved cell signaling system present in most animals. Mammals possess four different notch receptors, referred...
    88 KB (10,270 words) - 03:00, 22 June 2024
  • Thumbnail for Glycogen synthase kinase-3 beta
    rtPA-induced hemorrhagic transformation and activates the Wnt/β-catenin signaling pathway after acute ischemic stroke in rats". Molecular Neurobiology...
    17 KB (1,819 words) - 16:52, 22 May 2024
  • Thumbnail for R-spondin 1
    female to male sex reversal. Furthermore, it promotes canonical WNT/β catenin signaling. The protein has two cysteine-rich, furin-like domains and one...
    8 KB (913 words) - 16:46, 15 October 2023
  • Thumbnail for Adenomatous polyposis coli
    attachment and signaling. The activity of one protein in particular, beta-catenin, is controlled by the APC protein (see: Wnt signaling pathway). Regulation...
    28 KB (3,225 words) - 01:48, 6 May 2024
  • Thumbnail for TCF7L1
    beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains...
    7 KB (892 words) - 02:50, 19 December 2023
  • Thumbnail for DKK2
    its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular...
    4 KB (479 words) - 09:43, 8 January 2024
  • Thumbnail for TCF7L2
    TCF7L2 (category Signal transduction)
    transcription factors can have large effects on the Wnt signalling pathway. Stimulation of the Wnt signaling pathway leads to the association of β-catenin with...
    45 KB (4,389 words) - 03:17, 8 July 2024
  • Thumbnail for AXIN1
    regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of...
    17 KB (2,159 words) - 03:07, 11 July 2024
  • Thumbnail for DKK1
    embryonic development through its inhibition of the Wnt signaling pathway. Dickkopf WNT signaling pathway inhibitor 1 (Dkk1) is a protein-coding gene that...
    16 KB (1,886 words) - 08:50, 17 May 2024
  • Thumbnail for Secreted frizzled-related protein 1
    also able to downregulate Wnt signaling by the formation of an inhibitory complex with the Frizzled receptors. The Wnt pathway plays a key role in embryonic...
    48 KB (6,317 words) - 19:53, 5 January 2024