2,5-Diketopiperazine is an organic compound with the formula (NHCH2C(O))2. The compound features a six-membered ring containing two amide groups at opposite...
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ethylenediamine. 2,5-Diketopiperazines are cyclodipeptides often obtainable via condensation of two α-amino acids. 2,6-Diketopiperazines may be viewed as...
4 KB (413 words) - 03:16, 28 November 2023
Tadalafil (category Diketopiperazines)
body of inhibiting PDE11 are not known. Tadalafil is an annulated 2,5-diketopiperazine. It is also a 1,2,3,4-tetrahydro-β-carboline. Tadalafil can be synthesized...
35 KB (3,244 words) - 03:49, 20 November 2024
synthesized by Emil Fischer and Ernest Fourneau in 1901 by boiling 2,5-diketopiperazine (glycine anhydride) with hydrochloric acid. Shaking with alkali and...
6 KB (393 words) - 17:18, 18 June 2024
Brevianamide F (category Diketopiperazines)
cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. It is the simplest member and the biosynthetic precursor of a large...
6 KB (560 words) - 16:41, 4 January 2024
Piscarinine (category Diketopiperazines)
piscarium Westling that belong to a class of naturally occurring 2,5-diketopiperazines. The cytotoxic dehydroproline tryptophan derivatives piscarinines...
2 KB (159 words) - 00:28, 7 April 2022
Verruculogen (category Diketopiperazines)
strains of aspergillus that belongs to a class of naturally occurring 2,5-diketopiperazines. It is an annulated analogue of cyclo(L-Trp-L-Pro) which belongs...
3 KB (198 words) - 14:34, 25 September 2023
pp. 225–256. ISBN 978-3-527-33107-9. Borthwick AD (July 2012). "2,5-Diketopiperazines: synthesis, reactions, medicinal chemistry, and bioactive natural...
7 KB (749 words) - 14:33, 28 May 2024
Spirotryprostatin A (category Diketopiperazines)
Spirotryprostatin A is an indolic alkaloid from the 2,5-Diketopiperazine class of natural products found in the Aspergillus fumigatus fungus. Spirotryprostatin...
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2CONHCH 2COO− + H2O Pyrolysis of glycine or glycylglycine gives 2,5-diketopiperazine, the cyclic diamide. Glycine forms esters with alcohols. They are...
40 KB (3,766 words) - 11:02, 30 October 2024
Partisi, Revolutionary Communard Party, Turkey Diketopiperazine, a class of organic compounds 2,5-Diketopiperazine, a specific form Duffin–Kemmer–Petiau algebra...
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Stephacidin (category Diketopiperazines)
of naturally occurring 2,5-diketopiperazines. This unusual family of fungal metabolites are complex bridged 2,5-diketopiperazine alkaloids that possess...
5 KB (516 words) - 01:26, 11 October 2021
Gliotoxin (category Diketopiperazines)
sulfur-containing mycotoxin that belongs to a class of naturally occurring 2,5-diketopiperazines produced by several species of fungi, especially those of marine...
31 KB (3,171 words) - 18:28, 7 June 2024
Cyclic glycine-proline (category Diketopiperazines)
small neuroactive peptide that belongs to a group of bioactive 2,5-diketopiperazines (2,5-DKPs) and is also known as cyclo-glycine-proline. cGP is a neutral...
19 KB (1,938 words) - 22:28, 20 October 2024
residue to the alpha amine of another). The smallest such species are 2,5-diketopiperazines, being derived from the cyclisation of a dipeptide. Cyclic isopeptides...
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acid Dihydrouracil, an intermediate in the catabolism of uracil 2,5-Diketopiperazine Ethyl diazoacetate, a reagent used in organic chemistry Muscimol...
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dipeptide derived from glycine and (R-)valine is converted into a 2,5-Diketopiperazine (a cyclic dipeptide). Double O-methylation gives the bis-lactim....
4 KB (444 words) - 19:38, 27 October 2022
Fumitremorgin (category Diketopiperazines)
Aspergillus and Penicillium that belong to a class of naturally occurring 2,5-diketopiperazines. Biosynthesis pathway of fumitremorgin pathway involves several...
5 KB (343 words) - 22:24, 20 November 2024
Bicyclomycin (category Diketopiperazines)
aizumenses in 1972. It belongs to a class of naturally occurring 2,5-diketopiperazines, that are among the most numerous of all the naturally occurring...
9 KB (839 words) - 21:35, 21 November 2023
cyclization to oxazolinones or - especially for dipeptides - to 2,5-diketopiperazines. Subirós-Funosas, R.; Prohens, R.; Barbas, R.; El-Faham, A.; Albericio...
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(October 2014). "Lysobacter capsici AZ78 produces cyclo(L-Pro-L-Tyr), a 2,5-diketopiperazine with toxic activity against sporangia of Phytophthora infestans and...
28 KB (3,434 words) - 13:08, 2 November 2024
Barettin (category Diketopiperazines)
tryptophan linked by two peptide bonds to an arginine residue, forming a 2,5-diketopiperazine nucleus. It is a cyclic dipeptide. Barettin is the major compound...
5 KB (403 words) - 01:59, 16 April 2024
Fellutanine (category Diketopiperazines)
diketopiperazine alkaloids isolated from the cultures of Penicillium fellutanum, that belongs to a class of naturally occurring 2,5-diketopiperazines...
2 KB (247 words) - 15:54, 17 April 2024
Retosiban (category Diketopiperazines)
series of 2,5 diketopiperazine oxytocin antagonists the (3S, 6S, 7S) isomer is >500 less active than the (3R, 6R, 7R)-isomer. In addition to the 2,5 diketopiperazine...
10 KB (1,099 words) - 16:40, 19 December 2023
been employed as the enolate-forming component of the condensation. 2,5-Diketopiperazine can be used as a methylene component as well; its condensation products...
5 KB (578 words) - 12:26, 26 March 2023
Roquefortine C (category Diketopiperazines)
C is a mycotoxin that belongs to a class of naturally occurring 2,5-diketopiperazines produced by various fungi, particularly species from the genus Penicillium...
7 KB (566 words) - 20:24, 29 January 2023
Rugulosuvine (category Diketopiperazines)
naturally occurring 2,5-diketopiperazines. Kozlovskiĭ AG, Adanin VM, Dahse HM, Grafe U (2001). "[Rugulosuvines A and B--diketopiperazine alkaloids from Penicillium...
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induce the formation of scabs on potato tubers. They are classed as 2,5-Diketopiperazines, with the most abundant having the chemical formula C22H22N406....
29 KB (3,293 words) - 15:19, 2 November 2024
Rhodotorulic acid (category Diketopiperazines)
Rhodotorulic acid is the smallest of the 2,5-diketopiperazine family of hydroxamate siderophores which are high-affinity chelating agents for ferric iron...
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Spirotryprostatin B (category Diketopiperazines)
fumigatus fungus that belongs to a class of naturally occurring 2,5-diketopiperazines.[1] Spirotryprostatin B and several other indolic alkaloids (including...
10 KB (871 words) - 01:03, 20 June 2023