• Thumbnail for Microtubule
    Microtubules are polymers of tubulin that form part of the cytoskeleton and provide structure and shape to eukaryotic cells. Microtubules can be as long...
    64 KB (7,838 words) - 06:58, 22 February 2024
  • Thumbnail for Spindle apparatus
    composed of hundreds of proteins. Microtubules comprise the most abundant components of the machinery. Attachment of microtubules to chromosomes is mediated...
    28 KB (3,300 words) - 00:23, 13 August 2024
  • The microtubule-organizing center (MTOC) is a structure found in eukaryotic cells from which microtubules emerge. MTOCs have two main functions: the organization...
    9 KB (1,113 words) - 23:36, 11 December 2023
  • Thumbnail for Tau protein
    from the gene MAPT (microtubule-associated protein tau). They have roles primarily in maintaining the stability of microtubules in axons and are abundant...
    55 KB (6,238 words) - 00:35, 11 August 2024
  • In cell biology, microtubule nucleation is the event that initiates de novo formation of microtubules (MTs). These filaments of the cytoskeleton typically...
    13 KB (1,601 words) - 07:11, 22 February 2024
  • In cell biology, microtubule-associated proteins (MAPs) are proteins that interact with the microtubules of the cellular cytoskeleton. MAPs are integral...
    12 KB (1,558 words) - 17:50, 6 July 2024
  • Thumbnail for Cytoskeleton
    of three main components: microfilaments, intermediate filaments, and microtubules, and these are all capable of rapid growth or disassembly depending on...
    45 KB (5,121 words) - 06:34, 27 May 2024
  • Thumbnail for Mitotic inhibitor
    A mitotic inhibitor, microtubule inhibitor, or tubulin inhibitor, is a drug that inhibits mitosis, or cell division, and is used in treating cancer, gout...
    59 KB (6,992 words) - 22:40, 13 August 2024
  • Thumbnail for Tubulin
    polymerize into microtubules, a major component of the eukaryotic cytoskeleton. It was discovered and named by Hideo Mōri in 1968. Microtubules function in...
    32 KB (3,393 words) - 05:32, 15 June 2024
  • Thumbnail for Orchestrated objective reduction
    objective reduction that is orchestrated by cellular structures called microtubules. It is proposed that the theory may answer the hard problem of consciousness...
    52 KB (5,761 words) - 20:41, 16 August 2024
  • Thumbnail for Motor protein
    microfilaments or microtubules. Actin motors such as myosin move along microfilaments through interaction with actin, and microtubule motors such as dynein...
    13 KB (1,538 words) - 23:48, 17 April 2024
  • Thumbnail for CAMSAP2
    the CAMSAP2 gene. CAMSAP2 possesses a microtubule-binding domain near the C-terminal region where "microtubule interactions" occur. On the C-terminal...
    22 KB (2,395 words) - 07:22, 18 August 2024
  • Thumbnail for Aster (cell biology)
    structure shaped like a star, consisting of a centrosome and its associated microtubules during the early stages of mitosis in an animal cell.: 221  Asters do...
    5 KB (643 words) - 05:35, 19 August 2022
  • Thumbnail for Guanosine triphosphate
    are added to the plus end of the growing microtubule. Such GTP hydrolysis is not mandatory for microtubule formation, but it appears that only GDP-bound...
    8 KB (607 words) - 10:33, 7 June 2024
  • Thumbnail for Microtubule-associated protein 2
    Microtubule-associated protein 2 is a protein in humans that is encoded by the MAP2 gene. This gene encodes a protein that belongs to the microtubule-associated...
    11 KB (1,380 words) - 17:46, 6 July 2024
  • Thumbnail for Kinesin
    class of motor proteins found in eukaryotic cells. Kinesins move along microtubule (MT) filaments and are powered by the hydrolysis of adenosine triphosphate...
    36 KB (4,235 words) - 11:32, 16 August 2024
  • Thumbnail for Treadmilling
    of the cytoskeletons of many cells, especially in actin filaments and microtubules. It occurs when one end of a filament grows in length while the other...
    12 KB (1,476 words) - 12:50, 22 July 2024
  • Thumbnail for Anaphase
    microtubules, and astral microtubules. The centromeres are split, and the sister chromatids are pulled toward the poles by kinetochore microtubules....
    6 KB (719 words) - 02:00, 2 May 2024
  • Katanin is a microtubule-severing AAA protein. It is named after the Japanese sword called a katana. Katanin is a heterodimeric protein first discovered...
    16 KB (1,693 words) - 01:52, 1 December 2023
  • Thumbnail for Axoneme
    molecular biology, an axoneme, also called an axial filament, is the microtubule-based cytoskeletal structure that forms the core of a cilium or flagellum...
    10 KB (1,263 words) - 15:58, 24 June 2024
  • Thumbnail for Protein filament
    protein filaments that make up the cytoskeleton include: actin filaments, microtubules and intermediate filaments. Compared to the other parts of the cytoskeletons...
    14 KB (1,806 words) - 22:50, 17 August 2024
  • Microtubule plus-end/positive-end tracking proteins or +TIPs are a type of microtubule associated protein (MAP) which accumulate at the plus ends of microtubules...
    8 KB (875 words) - 07:52, 27 May 2024
  • Thumbnail for Centrosome
    'body') (archaically cytocentre) is an organelle that serves as the main microtubule organizing center (MTOC) of the animal cell, as well as a regulator of...
    24 KB (2,577 words) - 11:55, 21 March 2024
  • Thumbnail for MACF1
    Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 is a protein that in humans is encoded by the MACF1 gene. MACF1 encodes a large protein containing...
    16 KB (2,169 words) - 23:11, 7 November 2023
  • Thumbnail for MAP4
    non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated...
    9 KB (1,156 words) - 03:30, 5 April 2024
  • Thumbnail for Mitosis
    Microtubules project from opposite ends of the cell, attach to the centromeres, and align the chromosomes centrally within the cell. The microtubules...
    71 KB (7,313 words) - 18:47, 21 August 2024
  • Thumbnail for MAP1B
    Microtubule-associated protein 1B is a protein that in humans is encoded by the MAP1B gene. This gene encodes a protein that belongs to the microtubule-associated...
    9 KB (1,060 words) - 18:59, 6 July 2024
  • The XMAP215/Dis1 family is a highly conserved group of microtubule-associated proteins (MAPs) in eukaryotic organisms. These proteins are unique MAPs...
    18 KB (2,171 words) - 09:23, 17 July 2024
  • Thumbnail for Dynein
    Dyneins are a family of cytoskeletal motor proteins that move along microtubules in cells. They convert the chemical energy stored in ATP to mechanical...
    29 KB (3,313 words) - 16:08, 3 December 2023
  • Thumbnail for Chemotherapy
    mercaptopurine. Anti-microtubule agents are plant-derived chemicals that block cell division by preventing microtubule function. Microtubules are an important...
    155 KB (17,546 words) - 16:49, 16 August 2024