Multiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces...
131 KB (13,509 words) - 07:49, 11 November 2024
Thus, some patients with smouldering myeloma progress to multiple myeloma and plasma cell leukemia. Smouldering myeloma, however, is not a malignant disease...
13 KB (1,570 words) - 13:38, 1 September 2024
an abnormal monoclonal proliferation of plasma cells, typically in multiple myeloma or Monoclonal gammopathy of undetermined significance. Other terms...
6 KB (693 words) - 17:17, 28 August 2024
Plasma cell dyscrasias (redirect from Non-IgM smoldering multiple myeloma)
a myeloma protein, i.e. an abnormal monoclonal antibody or portion thereof. The exception to this rule is the disorder termed non-secretory multiple myeloma;...
81 KB (10,828 words) - 17:41, 12 November 2024
The Multiple Myeloma Research Foundation (MMRF) is a charitable organization dedicated to multiple myeloma, an incurable blood cancer. The MMRF runs as...
3 KB (309 words) - 19:19, 5 March 2024
The mission of the Multiple Myeloma Research Consortium (MMRC) is to champion collaboration with and integration across academia and industry and to focus...
5 KB (478 words) - 19:42, 3 August 2024
found during standard laboratory blood or urine tests. MGUS resembles multiple myeloma and similar diseases, but the levels of antibodies are lower, the number...
19 KB (2,182 words) - 16:43, 21 September 2024
Lenalidomide (section Multiple myeloma)
a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). For multiple myeloma, it is a first line treatment...
29 KB (2,483 words) - 05:43, 9 August 2024
International Myeloma Working Group lists three types: solitary plasmacytoma of bone (SPB); extramedullary plasmacytoma (EP), and multiple plasmacytomas...
17 KB (1,939 words) - 09:26, 25 December 2023
monoclonal antibody medication. It binds to CD38, which is overexpressed in multiple myeloma cells. Daratumumab was originally developed by Genmab, but it is now...
22 KB (1,836 words) - 05:53, 21 September 2024
anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma. This includes multiple myeloma in those who have and have not previously...
24 KB (2,272 words) - 08:01, 11 November 2024
U.S. Food and Drug Administration (FDA) for use in newly diagnosed multiple myeloma (MM) under strict regulations. This has led to the development of a...
49 KB (5,487 words) - 11:41, 24 January 2024
RANKL (section Multiple myeloma)
migration (i.e. chronic lymphocytic leukemia (CLL) and multiple myeloma). Among patients with multiple myeloma, RANKL activity was greatly increased. In fact...
28 KB (3,305 words) - 13:29, 8 November 2024
others, is an oral medication used to treat a number of cancers (e.g., multiple myeloma), graft-versus-host disease, and many skin disorders (e.g., complications...
76 KB (7,432 words) - 14:59, 21 November 2024
Osteoprotegerin (section Multiple myeloma)
resorption. Multiple myeloma is a type of cancer involving malignant plasma cells, called myeloma cells, within the bone marrow. Multiple myeloma is associated...
30 KB (3,687 words) - 20:28, 17 May 2024
Sarclisa, is a monoclonal antibody (mAb) medication for the treatment of multiple myeloma. The most common side effects include neutropenia (low levels of neutrophils...
32 KB (3,304 words) - 19:28, 14 November 2024
Elotuzumab (section Multiple myeloma)
adults that have received 1 to 3 prior therapies for the treatment of multiple myeloma. It is also indicated for adult patients in combination with pomalidomide...
14 KB (1,196 words) - 14:55, 2 July 2024
the brand name Elrexfio, is a medication used for the treatment of multiple myeloma. Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed...
12 KB (821 words) - 02:57, 12 October 2024
infections, some kidney diseases and some cancers (such as lymphoma and multiple myeloma). The ESR is decreased in polycythemia, hyperviscosity, sickle cell...
25 KB (2,814 words) - 23:51, 13 November 2024
Talvey, is a humanized monoclonal antibody used for the treatment of multiple myeloma. It is a bispecific GPRC5D-directed CD3 T-cell engager. Talquetamab...
14 KB (1,157 words) - 13:55, 3 September 2024
7 victory during the 2016 World Series. Hunt is a supporter of the Multiple Myeloma Research Foundation, of which she is an honorary board member. "About...
23 KB (1,414 words) - 17:37, 16 November 2024
The FDA approved carfilzomib in July 2012, for use in people with multiple myeloma who have received at least two prior therapies, including treatment...
19 KB (1,730 words) - 05:43, 7 April 2024
Donald Rumsfeld (category Deaths from multiple myeloma in the United States)
presidential election dispute. On June 29, 2021, Rumsfeld died from multiple myeloma at his home in Taos, New Mexico. Following a private funeral at Fort...
182 KB (16,739 words) - 11:37, 20 November 2024
suggestive of multiple myeloma, or Waldenström's macroglobulinemia.[citation needed] Bence Jones proteins are particularly diagnostic of multiple myeloma in the...
6 KB (607 words) - 08:18, 18 January 2024
human plasma cells. It is also expressed on malignant plasma cells in multiple myeloma. Compared with CD138, which disappears rapidly ex vivo, the expression...
24 KB (2,793 words) - 18:41, 30 May 2024
most popular antigen target, followed by BCMA (commonly expressed in multiple myeloma). In 2016, studies began to explore the viability of other antigens...
83 KB (8,772 words) - 12:11, 21 November 2024
formed as a symptom of specific diseases, including breast cancer and multiple myeloma. This softened area appears as a hole on X-ray scans due to decreased...
6 KB (673 words) - 17:26, 24 September 2024
immunoproliferative disorder or hematologic neoplasms, especially multiple myeloma. It is sometimes considered equivalent to plasma cell dyscrasia. The...
7 KB (684 words) - 06:22, 20 September 2023
monoclonal gammopathy of undetermined significance, which can progress into multiple myeloma or myelodysplastic syndrome. and cervical dysplasia, which can progress...
15 KB (1,344 words) - 23:16, 29 March 2024
through clinical trials to approval for treatment of patients with multiple myeloma by the U.S. FDA, but has a growing clinical development pipeline of...
13 KB (1,244 words) - 02:54, 21 May 2024