An oncolytic virus is a virus that preferentially infects and kills cancer cells. As the infected cancer cells are destroyed by oncolysis, they release...

such as ICP34.5, ICP6/UL39, and ICP47. HSV1716 is a first generation oncolytic virus developed by the Glasgow Institute of Virology, and subsequently by...

convert viruses into therapeutic agents by reprogramming viruses to treat diseases. There are three main branches of virotherapy: anti-cancer oncolytic viruses...

vector for gene therapy and also as an oncolytic virus. Of the many different viruses being explored for oncolytic potential, an adenovirus was the first...

Clinic the following year. In 2019 the company then licensed the CF33 oncolytic virus platform, invented by renowned oncologist Professor Yuman Fong of City...

T-Vec is the first FDA-approved oncolytic virus for the treatment of melanoma. A number of other oncolytic viruses are in Phase II-III development. Certain...

Adeno-associated virus (AAV) has been researched as a viral vector in gene therapy for cancer treatment as an oncolytic virus. Currently there are not...

herpes virus (an oncolytic herpes virus). Two genes were removed – one that shuts down an individual cell's defenses, and another that helps the virus evade...

wild-type Coxsackievirus A21, is being used in human clinical trials as an oncolytic virus. SCAR-Fc (Soluble Receptor Analogue) is an experimental prophylactic...

acquire ViraTherapeutics for €210 million ($230 million), a developer of oncolytic virus therapies, dependent on the success of Phase I trials. In June 2016...

Since Semliki Forest virus naturally infects cells of the central nervous system, it has been pre-clinically tested as an oncolytic virus against the very...

JX-594 is an oncolytic virus is designed to target and destroy cancer cells. It is also known as Pexa-Vec, INN pexastimogene devacirepvec) and was constructed...

Oncolytics Biotech Inc. is a Canadian company headquartered in Calgary, Alberta, that is developing an intravenously delivered immuno-oncolytic virus...

the virus gained approval for the treatment of melanoma in late 2015. Viruses that have been reprogrammed to kill cancer cells are called oncolytic viruses...

respective approaches: myvac (therapeutic vaccines) and Invir.IO (oncolytic viruses). Transgene’s portfolio consists of four products currently in clinical...

Oncogenic Oncogene Adult T-cell leukemia/lymphoma Cancer bacteria Oncolytic virus, a virus that infects and kills cancer cells Gag-onc fusion protein List...

prototypes Oncolytic virus Human trials (Talimogene laherparepvec, reolysin, JX-594), commercialisation (H101) Cancer therapy, imaging Oncolytic virus Personalized...

virus refers to: An oncovirus, a virus that can cause cancer. Also generally the role of viruses in carcinogenesis. On the other hand to an oncolytic...

the clinical grade formulation of the laboratory strain GLV-1h68, an oncolytic virus developed by Genelux Corporation. GL-ONC1 is currently under evaluation...

genetically modified oncolytic viruses that show promise as treatments for various types of cancer. Most vaccines consist of viruses that have been attenuated...

tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus". Nature Medicine. 6 (7): 821–5. doi:10.1038/77558. PMID 10888934....

combined with other immunotherapies. Double-stranded RNA viruses Oncolytic virus Orphan virus "Viral Zone". ExPASy. Retrieved 15 June 2015. Guglielmi,...

oncolytic vaccinia virus, modified to increase its safety, tumor selectivity and therapeutic potential. Vaccinia virus is a non-human pathogen. Virus-mediated...

in the field of oncolytic viruses, that is, viruses that preferentially infect and kill cancer cells. The company's oncolytic virus product, called Cavatak...

mutant type 2 herpes simplex virus deleted for the protein kinase domain of the ICP10 gene is a potent oncolytic virus". Molecular Therapy. 13 (5): 882–90...

Measles virus encoding the human thyroidal sodium iodide symporter or MV-NIS is an attenuated oncolytic Edmonston (Ed) strain of measles virus. MV-NIS...

PMID 22149027. Garber K (March 2006). "China approves world's first oncolytic virus therapy for cancer treatment". Journal of the National Cancer Institute...

in research as a model pathogen. The virus is infectious for many cancer cell lines (see below), and has oncolytic properties demonstrated in animal models...

Crops Animals Bacteria and viruses Ice-minus bacteria Hepatitis B vaccine Oncolytic virus...

biopharmaceutical company that developed the oncolytic viruses JX-594 and JX-929 among others. By creating oncolytic viruses that can (1) kill tumor cells directly...