• Thumbnail for Statin
    Statins (or HMG-CoA reductase inhibitors) are a class of medications that lower cholesterol. They are prescribed typically to people who are at high risk...
    134 KB (13,069 words) - 00:18, 30 December 2024
  • HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase inhibitors, called statins, was a breakthrough in the prevention of hypercholesterolemia and related...
    23 KB (2,423 words) - 18:34, 11 September 2024
  • Thumbnail for Atorvastatin
    Atorvastatin (category Statins)
    Atorvastatin is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. For the prevention...
    100 KB (9,454 words) - 15:22, 12 November 2024
  • Thumbnail for Rosuvastatin
    Rosuvastatin (category Statins)
    Rosuvastatin, sold under the brand name Crestor among others, is a statin medication, used to prevent cardiovascular disease in those at high risk and...
    42 KB (3,484 words) - 07:01, 29 December 2024
  • Thumbnail for Ezetimibe
    Generally it is used together with dietary changes and a statin. Alone, it is less preferred than a statin. It is taken by mouth. It is also available in the...
    20 KB (1,872 words) - 07:01, 29 December 2024
  • Statin-associated autoimmune myopathy (SAAM), also known as anti-HMGCR myopathy, is a very rare form of muscle damage caused by the immune system in people...
    12 KB (1,349 words) - 18:07, 19 March 2024
  • Thumbnail for Coenzyme Q10
    an adjunctive therapy to reduce inflammation in periodontitis. Although statins may reduce CoQ10 in the blood it is unclear if they reduce CoQ10 in muscle...
    49 KB (4,902 words) - 17:13, 28 December 2024
  • Hydroxymethylglutaryl-coenzyme A reductase inhibitors (HMG-CoA inhibitors or statins) Statins may sometimes cause myalgia and cramps among other possible side effects...
    19 KB (2,017 words) - 15:04, 31 October 2024
  • Thumbnail for Fenofibrate
    commonly used compared to statins because it treats a different type of cholesterol abnormality to statins. While statins have strong evidence for reducing...
    26 KB (2,514 words) - 06:51, 30 December 2024
  • Thumbnail for Red yeast rice
    the United States and other countries. Lovastatin and other prescription statin drugs inhibit cholesterol synthesis by blocking action of the enzyme HMG-CoA...
    24 KB (2,917 words) - 03:29, 31 October 2024
  • Thumbnail for Simvastatin
    Simvastatin (category Statins)
    Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. It is used along with exercise, diet, and...
    33 KB (3,277 words) - 00:33, 1 September 2024
  • with a statin or statin with other lipid-lowering therapies in patients unable to reach LDL-C goals with the maximum tolerated dose of a statin; or alone...
    18 KB (1,589 words) - 07:00, 29 December 2024
  • low risk, the use of statin therapy depends on individual patient factors such as age, cholesterol levels, and risk factors. Statins are considered the...
    31 KB (3,036 words) - 00:18, 13 December 2024
  • Thumbnail for HMG-CoA reductase
    widely available cholesterol-lowering drugs known collectively as the statins, which help treat dyslipidemia. HMG-CoA reductase is anchored in the membrane...
    34 KB (4,113 words) - 16:29, 29 July 2024
  • specifically PPARα, to decrease free fatty acid production. Statin drugs, especially the synthetic statins (atorvastatin and rosuvastatin) can decrease LDL levels...
    47 KB (4,549 words) - 01:05, 22 December 2024
  • Thumbnail for Cholesterol
    begins with the mevalonate or HMG-CoA reductase pathway, the target of statin drugs, which encompasses the first 18 steps. This is followed by 19 additional...
    80 KB (8,656 words) - 19:58, 29 December 2024
  • and beta-blockers.   Antihyperlipidemic agents most often prescribed are statins, ezetimibe and fibrates. They either lower low-density lipoprotein cholesterol...
    46 KB (5,038 words) - 04:38, 5 December 2024
  • Thumbnail for Erythromycin
    Erythromycin (redirect from Erythro-Statin)
    Erythromycin is an antibiotic used for the treatment of a number of bacterial infections. This includes respiratory tract infections, skin infections,...
    42 KB (3,915 words) - 08:50, 21 December 2024
  • with a statin or statin with other lipid-lowering therapies in people unable to reach LDL-C goals with the maximum tolerated dose of a statin, or alone...
    21 KB (1,744 words) - 14:15, 24 April 2024
  • 2018 by the American College of Cardiology & American Heart Association. Statins (HMG-CoA reductase inhibitors) are particularly well suited for lowering...
    11 KB (1,252 words) - 19:58, 24 December 2024
  • Thumbnail for Amlodipine/atorvastatin
    the treatment of high cholesterol and high blood pressure. It contains a statin and a calcium channel blocker. Amlodipine/atorvastatin is marketed under...
    4 KB (196 words) - 06:06, 17 June 2024
  • Thumbnail for Niacin
    for decreasing the risk of cardiovascular disease in those already on a statin. A 2010 review had concluded that niacin was effective as a mono-therapy...
    92 KB (8,787 words) - 13:29, 26 December 2024
  • Thumbnail for Hypercholesterolemia
    cholesterol levels in the blood. Statins are the typically used medications, in addition to healthy lifestyle interventions. Statins can reduce total cholesterol...
    61 KB (6,215 words) - 19:38, 30 October 2024
  • Thumbnail for Ischemia
    (2015-10-13). "Clinical Effectiveness of Statin Therapy After Ischemic Stroke: Primary Results From the Statin Therapeutic Area of the Patient-Centered...
    23 KB (2,333 words) - 09:54, 14 October 2024
  • Thumbnail for Akira Endo (biochemist)
    relationship between fungi and cholesterol biosynthesis led to the development of statin drugs, which are some of the best-selling pharmaceuticals in history. Endo...
    10 KB (862 words) - 08:11, 12 December 2024
  • trial designed to assess the efficacy of niacin (extended-release) added to statin therapy in reducing cardiovascular events in patients with established atherosclerotic...
    6 KB (635 words) - 12:29, 26 December 2024
  • Thumbnail for Pravastatin
    Pravastatin (category Statins)
    Pravastatin, sold under the brand name Pravachol among others, is a statin medication, used for preventing cardiovascular disease in those at high risk...
    14 KB (1,096 words) - 19:44, 21 September 2024
  • Thumbnail for Fibrate
    particles, with or without high LDL-C levels. Fibrates may be compared to statin drugs, which reduce LDL-cholesterol (LDL-C) and have only limited effects...
    10 KB (1,091 words) - 01:14, 8 October 2024
  • Thumbnail for Combined hyperlipidemia
    specifically PPARα, to decrease free fatty acid production. Statin drugs, especially the synthetic statins (atorvastatin and rosuvastatin), can decrease LDL levels...
    4 KB (371 words) - 01:03, 22 December 2024
  • Thumbnail for Myositis
    that can cause myositis are statins, which are used to lower cholesterol levels. One of the most common side effects of statin therapy is muscle pain which...
    11 KB (1,023 words) - 01:09, 13 November 2024