Folate, also known as vitamin B9 and folacin, is one of the B vitamins. Manufactured folic acid, which is converted into folate by the body, is used as...
105 KB (11,280 words) - 14:27, 12 November 2024
Folate deficiency, also known as vitamin B9 deficiency, is a low level of folate and derivatives in the body. This may result in megaloblastic anemia in...
29 KB (3,176 words) - 07:22, 2 November 2024
Anemia (redirect from Dietary folate deficiency anaemia)
blood donation. Causes of decreased production include iron deficiency, folate deficiency, vitamin B12 deficiency, thalassemia and a number of bone marrow...
87 KB (8,877 words) - 16:19, 6 November 2024
Folate receptors bind folate and reduced folic acid derivatives and mediates delivery of tetrahydrofolate to the interior of cells. It is then converted...
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vitamin, folate (folic acid), to a molecule/drug to form a "folate conjugate". Based on the natural high affinity of folate for the folate receptor protein...
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by name than by number, such as pantothenic acid (B5), biotin (B7), and folate (B9). B vitamins are present in protein-rich foods, such as fish, poultry...
43 KB (2,802 words) - 19:28, 11 November 2024
Folate receptor 1 (Folate receptor alpha, FOLR1) is a protein that in humans is encoded by the FOLR1 gene. The protein encoded by this gene is a member...
15 KB (1,733 words) - 06:11, 25 April 2024
Reduced Folate Carrier (RFC) Family (TC# 2.A.48) is a group of transport proteins that is part of the major facilitator superfamily. RFCs take up folate, reduced...
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Neural tube defect (section Folate deficiency)
which has decreased from around 5 per 10,000 (0.05% of US births) since folate fortification of grain products was started. The number of deaths in the...
50 KB (5,814 words) - 12:37, 7 June 2024
Cerebral folate deficiency is a condition in which concentrations of 5-methyltetrahydrofolate are low in the brain as measured in the cerebral spinal fluid...
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Hereditary folate malabsorption (HFM) is a rare autosomal recessive disorder caused by loss-of-function mutations in the proton-coupled folate transporter...
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Antifolate (redirect from Folate antagonists)
such as proguanil, pyrimethamine and trimethoprim selectively inhibit folate's actions in microbial organisms such as bacteria, protozoa and fungi. The...
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intermediate interferes with the normal bacterial synthesis of folic acid (folate). Folate is an essential metabolite for bacterial growth and replication because...
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spinal cord strongly suggests the presence of a B12 deficiency instead of folate deficiency. Methylmalonic acid, if not properly handled by B12, remains...
118 KB (13,024 words) - 16:27, 2 November 2024
4% chance that the next child will also be affected. Not having enough folate (vitamin B9) in the diet before and during pregnancy also plays a significant...
82 KB (9,145 words) - 01:59, 19 October 2024
Folate transporter 1 is a protein which in humans is encoded by the SLC19A1 gene. Transport of folate compounds into mammalian cells can occur via receptor-mediated...
12 KB (1,472 words) - 20:18, 27 November 2023
Prostate cancer (redirect from Prostate cancer folate supplementation)
Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder. Abnormal growth of prostate...
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concentration, as vitamin C is degraded by heating. Folate levels may also be decreased, as folate tends to leach into cooking liquid. Spinach is rich...
18 KB (1,957 words) - 21:50, 29 October 2024
Folate-binding protein (FBP) are proteins that bind folate, typically the folate receptors and reduced folate carrier. FBP can be a marker for ovarian...
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FOLR3 (redirect from Folate receptor gamma)
Folate receptor gamma is a protein that in humans is encoded by the FOLR3 gene. It is involved in up-take of folic acid. The FOLR multi-gene family (FOLR1...
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– Iron deficiency, sickle cell anemia Anisocytosis with macrocytosis – Folate or vitamin B12 deficiency, autoimmune hemolytic anemia, cytotoxic chemotherapy...
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causes from an anemia of a single cause. Deficiencies of Vitamin B12 or folate produce a macrocytic anemia (large cell anemia) in which the RDW is elevated...
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Neurulation (redirect from Neural tube defect, folate-sensitive)
1186/s12976-016-0037-2 Björklund, NK, Gordon, R A hypothesis linking low folate intake to neural tube defects due to failure of post-translation methylations...
26 KB (3,288 words) - 20:50, 23 September 2024
most often due to hypovitaminosis, specifically vitamin B12 deficiency or folate deficiency. Loss of micronutrients may also be a cause. Megaloblastic anemia...
13 KB (1,250 words) - 09:07, 6 November 2024
skin pigmentation was the breakdown of folate in reaction to ultraviolet radiation; the relationship between folate breakdown induced by ultraviolet radiation...
75 KB (8,509 words) - 10:46, 25 October 2024
beta-lactam-betalactamase inhibitor combinations (such as piperacillin-tazobactam), folate antagonists, quinolones, and carbapenems. Many of these antibiotics also...
24 KB (2,445 words) - 22:33, 4 September 2024
Food fortification (section Folate)
naturally-occurring forms of folate, and which only contributes a minor amount to the folates occurring in natural foods. In many cases, such as with folate, it is an open...
29 KB (3,313 words) - 16:01, 8 November 2024
The proton-coupled folate transporter is a protein that in humans is encoded by the SLC46A1 gene. The major physiological roles of PCFTs are in mediating...
22 KB (2,649 words) - 18:32, 9 June 2024
foods. Vitamin fortification programs exist in one or more countries for folate, niacin, riboflavin, thiamin, vitamin A, vitamin B6, vitamin B12, vitamin...
49 KB (3,959 words) - 23:35, 27 October 2024
Levomefolic acid (category Folates)
(6S)-5-methyltetrahydrofolate, and (6S)-5-MTHF) is the primary biologically active form of folate used at the cellular level for DNA reproduction, the cysteine cycle and...
15 KB (1,173 words) - 11:42, 25 June 2024