biochemistry, the active site is the region of an enzyme where substrate molecules bind and undergo a chemical reaction. The active site consists of amino...

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enzyme's active site. The remaining majority of the enzyme structure serves to maintain the precise orientation and dynamics of the active site. In some...

Active Duty porn site. In 2009, Active Duty formally requested a news article be rescinded because it possibly provided the actual name of an active duty...

allosteric modulator) is a substance that binds to a site on an enzyme or receptor distinct from the active site, resulting in a conformational change that alters...

facilitates a specific chemical reaction by binding the substrate to its active site, a specialized area on the enzyme that accelerates the most difficult...

make glucose-6-phosphate. Active site residues of hexokinase allow for stabilization of the glucose molecule in the active site and spur the onset of an...

the natural substrate ornithine from accessing the active site (Figure 1). Within the active site of ODC, eflornithine undergoes decarboxylation with...

tissues of the body but are at the highest concentration in the liver. The active site of the aldehyde dehydrogenase enzyme is largely conserved throughout...

requirement for L-DOPA as cofactor. The two copper atoms within the active site of tyrosinase enzymes interact with dioxygen to form a highly reactive...

Mg2+ in the active site of the enzyme involves addition of an "activating" carbon dioxide molecule (CO2) to a lysine in the active site (forming a carbamate)...

dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). The active site of most carbonic anhydrases contains a zinc ion. They are therefore classified...

repeating α-β subunits, each coupled pair of subunits has an active site, for a total of 12 active sites. It plays an essential function for survival, neutralizing...

while within the active site (e.g. hydrogen bonding or van der Waals forces). Specific and favorable bonding occurs within the active site until the substrate...

IDH has two active sites. Each active site binds a NAD+/NADP+ molecule and a divalent metal ion (Mg2+,Mn2+). In general, each active site has a conserved...

(not shown here) in the active site. The amino acids are shown as wires, and the TPP is in ball and stick form. The active site also aids in the transfer...

motifs which may covalently bind to the acetylcholinesterase enzyme's active site in several places, perhaps explaining the rapid denaturing of the enzyme...

site contains a water molecule or a dioxygen molecule. By contrast the protein myoglobin, found in muscle cells, has only one such unit. The active site...

development, the excipients are chosen carefully so that the active ingredient can reach the target site in the body at the desired rate and extent.[citation...

substrate. This is accomplished by blocking the binding site of the substrate – the active site – by some means. The Vmax indicates the maximum velocity...

newer class of medication, directly inhibit thrombin by binding to its active site. Recombinant thrombin is available as a powder for reconstitution into...

into one of several families based on their active site mechanism. Enzymes that use a metal in the active site are called "metallo-carboxypeptidases" (EC...

Cre does not form a shared active site between separate subunits and all the residues that contribute to the active site are found on a single subunit...

has two zinc atoms per subunit. One is the active site, which is involved in catalysis. In the active site, the ligands are Cys-46, Cys-174, His-67, and...

acetyl-CoA. Pyruvate decarboxylase occurs as a dimer of dimers with two active sites shared between the monomers of each dimer. The enzyme contains a beta-alpha-beta...

serotonin. Instead of binding to the active site on the serotonin transporter, they bind to an allosteric site, which exerts its effects by causing conformational...

heterogeneous catalyst has active sites, which are the atoms or crystal faces where the substrate actually binds. Active sites are atoms but are often described...

effects by binding to the active site or to the allosteric site on a receptor, or they may interact at unique binding sites not normally involved in the...

Pepsin is an aspartic protease, using a catalytic aspartate in its active site. It is one of three principal endopeptidases (enzymes cutting proteins...

other loops, are part of the major subdomain that surround the active site. The active site is situated in the N-terminal half of the sequence, which includes...