Thalidomide, sold under the brand names Contergan and Thalomid among others, is an oral medication used to treat a number of cancers (e.g., multiple myeloma)...

In the late 1950s and early 1960s, the use of thalidomide in 46 countries by women who were pregnant or who subsequently became pregnant resulted in the...

cause of phocomelia is the mother being prescribed the use of the drug thalidomide during pregnancy; however, the causes of most cases are to be determined...

the U.S. Food and Drug Administration (FDA), she refused to authorize thalidomide for market because she had concerns about the lack of evidence regarding...

immune responses) containing an imide group. The IMiD class includes thalidomide and its analogues (lenalidomide, pomalidomide, mezigdomide and iberdomide)...

Chemical agents Prescription and recreational drugs (e.g., alcohol, thalidomide) Environmental toxins and contaminants (e.g., heavy metals such as mercury...

considered a side effect. For information regarding birth defects, see thalidomide. Somnolence (drowsiness; ~40%) Edema (~60%) Hypotension (low blood pressure)...

the teratogenic drug thalidomide, marketed as the sleeping pill Contergan and promoted as a morning sickness preventive. Thalidomide caused severe birth...

English rock musician, actor, writer and performance artist. He has thalidomide-induced phocomelia. Between 1980 and 1995 Fraser was a drummer with several...

example of the importance of stereochemistry relates to the thalidomide disaster. Thalidomide is a pharmaceutical drug, first prepared in 1957 in Germany...

Canadian paralympic gold medallist swimmer, and thalidomide survivor. She was president of the Thalidomide Victims Association of Canada in 2019. Lake was...

Wonder Drug: The Secret History of Thalidomide in America and Its Hidden Victims is a nonfiction book authored by Jennifer Vanderbes and published by...

1962) is an English thalidomide survivor and activist. She is a past chair of the National Advisory Committee of the Thalidomide Trust, the organisation...

Thalidomide!! A Musical is a British musical written and composed by Mat Fraser, who was born with phocomelia as a result of the drug thalidomide being...

a British thalidomide survivor, painter, lace maker, and carriage driver with the RDA. Mercer was a representative of the global thalidomide community...

Australian obstetrician. He published a letter on the teratogenicity of thalidomide following the findings of a midwife named Pat Sparrow, which resulted...

adjusted in people with kidney problems. Lenalidomide is closely related to thalidomide, which is known to cause severe birth defects, so its use during pregnancy...

the other enantiomer is harmful, like salbutamol and thalidomide. The (R) enantiomer of thalidomide is effective against morning sickness, while the (S)...

wildly in their pharmacokinetic, pharmacodynamic profile. The tragedy of thalidomide illustrates the potential for extreme consequences resulting from the...

thalidomide was first made available on 1 October 1957, and it became the second best-selling medication in Germany after Bayer Aspirin. Thalidomide was...

seek compensation for mothers who had taken the morning sickness drug thalidomide, which led to their children having severely deformed limbs. In 1984...

following the thalidomide disaster the development and licensing of drugs changed dramatically. First synthesized in 1953, thalidomide was widely prescribed...

activity of thalidomide in the chick and zebrafish was cast into doubt due to a 2013 report that pomalidomide (a more potent thalidomide analogue) does...

compound of pomalidomide, thalidomide, was originally discovered to inhibit angiogenesis in 1994. Based upon this discovery, thalidomide was taken into clinical...

deficiency), drugs (e.g. anticancer drugs, tetracyclines, many hormones, thalidomide), and environmental chemicals (e.g. mercury, lead, dioxins, PBDEs, HBCD...

as thalidomide. A prosthesis can be given to compensate for the missing limb(s). Amniotic band constriction Dysmelia Hemimelia Phocomelia Thalidomide Bowen...

gain support for the survivors of thalidomide. Her efforts resulted in life-time compensation for Canadian "thalidomiders", as well as a special fund for...

response to the thalidomide tragedy, in which thousands of children were born with birth defects as a result of their mothers taking thalidomide for morning...

treat and therapies include steroids, dupilumab, vitamins, cryosurgery, thalidomide, and UVB light[citation needed]. In the event that staphylococcus or...

antagonist. Racemization of pharmaceutical drugs can occur in vivo. Thalidomide as the (R) enantiomer is effective against morning sickness, while the...