Plasma gelsolin (pGSN) is an 83 kDa abundant protein constituent of normal plasma and an important component of the innate immune system. The identification...

closely related secreted form, Plasma gelsolin, that contains an additional 24 AA N-terminal extension. Plasma gelsolin's ability to sever actin filaments...

presentations deriving from the aberrant proteolysis of a mutated form of plasma gelsolin. First described in 1969 by the Finnish ophthalmologist Jouko Meretoja...

filamin and plasma gelsolin, that regulate the assembly of actin. Gelsolin is also an abundant extracellular protein that circulates in blood plasma, and Stossel...

Kobzik L (September 2019). "Delayed Administration of Recombinant Plasma Gelsolin Improves Survival in a Murine Model of Penicillin-Susceptible and...

glyoxylate redasductase/hydroxypyruvate reductase GSN: cytoplasmic and plasma gelsolin HAUS6: HAUS augmin-like complex subunit 6 HEMGN: encoding protein hemogen...

the SCIN gene. Scinderin is an actin severing protein belonging to the gelsolin superfamily. It was discovered in Dr. Trifaro's laboratory at the University...

myristoylated and involved in the regulation of apoptosis are actin and gelsolin. S-palmitoylation (i.e. attachment of palmitic acid) is a reversible protein...

where it prompts the release of cytochrome c leading to cell death. Actin, gelsolin and p21-activated kinase 2 PAK2 are three other proteins that are myristoylated...

DICTYOSTELIUM CAATP-ACTIN IN COMPLEX WITH GELSOLIN SEGMENT 1 1c0g: CRYSTAL STRUCTURE OF 1:1 COMPLEX BETWEEN GELSOLIN SEGMENT 1 AND A DICTYOSTELIUM/TETRAHYMENA...

numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin...

phosphatidylinositol 4,5-bisphosphate (PIP2), a phospholipid that is located in the plasma membrane, by phospholipase C (PLC). Together with diacylglycerol (DAG),...

annexin repeat. Several proteins consist of annexin with other domains like gelsolin. The basic structure of an annexin is composed of two major domains. The...

biomarker that can be measured with immunoassays in cerebrospinal fluid and plasma and reflects axonal damage in a wide variety of neurological disorders....

marker in the laboratory diagnosis of heart attack. It occurs in different plasma concentration but the same circumstances as troponin T - either test can...

phospholipid component of cell membranes. PtdIns(4,5)P2 is enriched at the plasma membrane where it is a substrate for a number of important signaling proteins...

amyloidosis Apolipoprotein AIV Familial amyloidosis of the Finnish type (FAF) Gelsolin Lysozyme amyloidosis Lysozyme Fibrinogen amyloidosis Fibrinogen Dialysis...

regions, affecting the organ's ability to filter and excrete waste and retain plasma protein. This can lead to high levels of protein in the urine (proteinuria)...

ions from intracellular stores, and/or when Ca2+ enters the cell through plasma membrane ion channels. Under certain conditions, the intracellular Ca2+...

is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of...

although the significance is unclear. TNIK has been shown to phosphorylate Gelsolin, a protein involved in F-actin depolymerisation thus inducing cytoskeletal...

genesis and maintenance of such structure. This association between the plasma membrane and the nuclear surface provides important implications for the...

transglutaminase which eventually form a cornified cell envelope beneath the plasma membrane terminal differentiation loss of nuclei and organelles, in the...

000 Dalton and are preferentially located on the cytosolic face of the plasma membrane. Annexin A1 protein has an apparent relative molecular mass of...

Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane in eukaryotic cells. Spectrin forms pentagonal or hexagonal arrangements...

JM, Manchester RD, Allen PG (2001). "VASP protects actin filaments from gelsolin: an in vitro study with implications for platelet actin reorganizations"...

with: ACTR3 ARPC2, CTNND1, FER, KCNA2, SHANK2, WASL, and WIPF1. actin gelsolin transferrin villin ENSG00000288401 GRCh38: Ensembl release 89: ENSG00000085733...

FBLN1 is the gene encoding fibulin-1, an extracellular matrix and plasma protein. Fibulin-1 is a secreted glycoprotein that is found in association with...

PMID 10190525. Neumayr G, Gaenzer H, Pfister R, et al. (February 2001). "Plasma levels of cardiac troponin I after prolonged strenuous endurance exercise"...

locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes, but it is always found intracellularly. Many of...