The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands...

coordinating many proteins at the site of replication, forming the replisome. The replisome is responsible for copying the entirety of genomic DNA in each...

molecular machine called the replisome. The following is a list of major DNA replication enzymes that participate in the replisome: In vitro single-molecule...

5'→3'. DNA Pol III is a component of the replisome, which is located at the replication fork. The replisome is composed of the following: 2 DNA Pol III...

most organisms, DNA polymerases function in a large complex called the replisome that contains multiple accessory subunits, such as the DNA clamp or helicases...

E coli replisome with a loop in lagging strand DNA...

different stages. During initiation, the replication machineries – termed replisomes – are assembled on DNA in a bidirectional fashion. These assembly loci...

gene and two 55 kDa accessory subunits encoded by the POLG2 gene. The replisome machinery is formed by DNA polymerase, TWINKLE and mitochondrial SSB proteins...

revealed the synergies between DNA polymerases and other molecules of the replisome (helicases and SSBs) and with the DNA replication fork. These results...

step in information transfer. A complex group of proteins called the replisome performs the replication of the information from the parent strand to...

"Structure and function of the GINS complex, a key component of the eukaryotic replisome". Biochemical Journal. 425 (3): 489–500. doi:10.1042/BJ20091531. Labib...

PMID 20478261. S2CID 26969788. Heller RC, Marians KJ (December 2006). "Replisome assembly and the direct restart of stalled replication forks". Nature...

replication. After the pre-RC is formed it must be activated and the replisome assembled in order for DNA replication to occur. In prokaryotes, DnaA...

3511. PMID 10698628. Shamoo Y, Steitz TA (October 1999). "Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA...

involved in DNA replication on each arm is called a replisome. At the forefront of the replisome is a DNA helicase that unwinds the two strands of DNA...

Repeat sequences Repetitive DNA Replica plating Replication fork Replicon Replisome Reporter gene Repressible operon Repression Repressor Reproductive cells...

Otterlei M (2012). "Nucleotide excision repair is associated with the replisome and its efficiency depends on a direct interaction between XPA and PCNA"...

region of DNA or RNA that replicates from a single origin of replication. replisome The entire complex of molecular machinery that carries out the process...

damage. Mechanisms that process damaged DNA in coordination with the replisome in order to maintain replication fork progression are considered to be...

core of the Cdc45-MCM-GINS helicase - the DNA unwinding engine of the replisome. Site selection for replication origins is carried out by the Origin Recognition...

(MCM) genes in 1984, which encode the catalytic core of the eukaryotic replisome. Tye also determined the first high-resolution structures of both the...

increases the rate of synthesis. Phage T7 has the simplest known DNA replisome, consisting of a helicase and primase that reside in a single polypeptide...

proteins associated with the replisome. There is some debate within the literature as to whether Rrm3p is part of the replisome or if it is a protein that...

reactive oxygen by transmembrane transporters, losing chromosomes by replisome binding, and stalling replication by transcription factors. For RNA lesions...

Alexander A.; Krasilnikova, Maria M.; Mirkin, Sergei M. (February 2009). "Replisome stalling and stabilization at CGG repeats, which are responsible for chromosomal...

reactive oxygen increase by transmembrane transporters, chromosome loss by replisome binding, replication stalling by transcription factors. The DDP human...

starting from the blood tissue descending into showing the DNA and the replisome. The "Hollow" instrument let the user tap different enzymes depicted in...

PMID 27241926. Bell SD (2012). "Archaeal Orc1/Cdc6 Proteins". The Eukaryotic Replisome: A Guide to Protein Structure and Function. Subcellular Biochemistry....

the cell cycle, DNA is usually most vulnerable during replication. The replisome must be able to navigate obstacles such as tightly wound chromatin with...

the replication of DNA—the T4 replisome Of particular importance is how multiple protein systems such as the replisomes responsible for DNA replication...